Target Name: LNX2
NCBI ID: G222484
Other Name(s): FLJ23932 | MGC46315 | ligand of numb-protein X 2 | PDZ domain-containing RING finger protein 1 | Ligand of Numb protein X 2 | Numb-binding protein 2 | Ligand of numb-protein X 2 | numb-binding protein 2 | FLJ12933 | LNX2_HUMAN | FLJ38000 | PDZ domain containing ring finger 1 | PDZRN1 | OTTHUMP00000018170

Understanding The Role of LNX2 in Disease

LNX2 (FLJ23932) is a protein that is expressed in various tissues of the body, including the brain, heart, kidneys, and liver. It is a member of the leucine-rich repeat (LRR) family of proteins, which are characterized by the presence of a leucine-rich repeat in their amino acid sequence. LNX2 is also known as 220kDa heat shock protein (HSP70) and has been shown to play a role in various cellular processes, including stress response, DNA damage repair, and inflammation.

Recent studies have suggested that LNX2 may be a drug target or biomarker for a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. This is because LNX2 has been shown to be involved in the development and progression of these conditions, and may be a useful target for therapeutic intervention.

One potential mechanism by which LNX2 may be involved in cancer is its role in cell signaling. LNX2 has been shown to play a negative role in the regulation of cell proliferation and has been shown to promote the growth inhibitory effect in various cancer cell lines. This suggests that LNX2 may be a useful target for cancer therapy.

Another potential mechanism by which LNX2 may be involved in neurodegenerative diseases is its role in the development of neurofibrillary tangles, which are thought to contribute to the development of Alzheimer's disease. LNX2 has been shown to be involved in the formation of these tangles and may be a useful biomarker for the diagnosis and treatment of neurodegenerative diseases.

In addition to its potential role in cancer and neurodegenerative diseases, LNX2 has also been suggested as a potential drug target for other conditions. For example, LNX2 has been shown to play a role in the regulation of inflammation, and may be a useful target for the treatment of autoimmune disorders.

Overall, LNX2 is a protein that has been shown to play a role in various cellular processes and may be a useful target for therapeutic intervention in a variety of conditions. Further research is needed to fully understand the role of LNX2 in disease and to develop effective treatments.

Protein Name: Ligand Of Numb-protein X 2

More Common Targets

LOC100127946 | LOC100127955 | LOC100128002 | LOC100128028 | LOC100128050 | LOC100128059 | LOC100128079 | LOC100128093 | LOC100128164 | LOC100128242 | LOC100128288 | LOC100128317 | LOC100128361 | LOC100128398 | LOC100128494 | LOC100128593 | LOC100128770 | LOC100128966 | LOC100128988 | LOC100129034 | LOC100129098 | LOC100129148 | LOC100129175 | LOC100129203 | LOC100129215 | LOC100129316 | LOC100129381 | LOC100129434 | LOC100129455 | LOC100129534 | LOC100129603 | LOC100129697 | LOC100130000 | LOC100130207 | LOC100130285 | LOC100130298 | LOC100130331 | LOC100130452 | LOC100130463 | LOC100130548 | LOC100130587 | LOC100130691 | LOC100130698 | LOC100130744 | LOC100130748 | LOC100130872 | LOC100130899 | LOC100130938 | LOC100130987 | LOC100130992 | LOC100131096 | LOC100131107 | LOC100131257 | LOC100131289 | LOC100131372 | LOC100131496 | LOC100131532 | LOC100131626 | LOC100131635 | LOC100131859 | LOC100131877 | LOC100131943 | LOC100132004 | LOC100132062 | LOC100132077 | LOC100132078 | LOC100132249 | LOC100132287 | LOC100132356 | LOC100132609 | LOC100132626 | LOC100132651 | LOC100132686 | LOC100132741 | LOC100132781 | LOC100132797 | LOC100133077 | LOC100133165 | LOC100133177 | LOC100133284 | LOC100133331 | LOC100133920 | LOC100134317 | LOC100134368 | LOC100134391 | LOC100134868 | LOC100190986 | LOC100233156 | LOC100240728 | LOC100240734 | LOC100240735 | LOC100271840 | LOC100272216 | LOC100272217 | LOC100286922 | LOC100287036 | LOC100287290 | LOC100287329 | LOC100287413 | LOC100287792