Target Name: CDC26
NCBI ID: G246184
Other Name(s): Cell division cycle protein 26 homolog | Anaphase-promoting complex subunit CDC26 | anaphase-promoting complex subunit 12 | Cell division cycle 26 | cell division cycle 26 homolog | anaphase-promoting complex subunit CDC26 | APC12 | Anaphase-promoting complex subunit 12 | cell division cycle protein 26 homolog | CDC26_HUMAN | cell division cycle 26 | C9orf17 | ANAPC12 | CDC26 subunit of anaphase promoting complex

CD26: A Potential Drug Target and Biomarker for Cell Division Cycle Protein 26 Homolog

CD26 is a protein that belongs to the cell division cycle protein 26 (CDC26) family. It is a 26kDa protein that plays a critical role in the cell division cycle, specifically in the G1 phase of the cell cycle. CD26 is composed of 215 amino acids and has a calculated pI of 9.97 nM. It is expressed in a variety of tissues, including skeletal muscles, heart, brain, andtestes.

CD26 functions as a negative regulator of the G1 checkpoint, which is a critical step in the cell division cycle where the cell prepares for cell division by duplicating its genetic material. The G1 checkpoint is a critical regulatory process that ensures that the cell has enough genetic material to divide. CD26 plays a vital role in regulating the amount of genetic material that can be duplicated during the G1 phase.

CD26 has been identified as a potential drug target and biomarker due to its unique structure and its involvement in the cell division cycle. In this article, we will discuss the biology of CD26, its functions, and its potential as a drug target.

Biography of CD26

CD26 is a 215 amino acid protein that has a calculated pI of 9.97 nM. It is expressed in a variety of tissues, including skeletal muscles, heart, brain, and testes. CD26 is a protein that belongs to the cell division cycle protein 26 (CDC26) family. The CDC26 family is characterized by the presence of a specific domain, known as the N-terminal hypervariable region (HVR), which is responsible for the unique structure and function of the protein.

CD26 is involved in the regulation of the cell division cycle, specifically in the G1 phase of the cell cycle. The G1 phase is a critical stage of the cell cycle where the cell prepares for cell division by duplicating its genetic material. The G1 checkpoint is a critical regulatory process that ensures that the cell has enough genetic material to divide. CD26 plays a vital role in regulating the amount of genetic material that can be duplicated during the G1 phase.

CD26 functions as a negative regulator of the G1 checkpoint. The G1 checkpoint is a critical step in the cell division cycle where the cell prepares for cell division by duplicating its genetic material. The G1 checkpoint is a regulatory process that ensures that the cell has enough genetic material to divide. CD26 plays a vital role in regulating the amount of genetic material that can be duplicated during the G1 phase.

CD26 has been identified as a potential drug target due to its unique structure and its involvement in the cell division cycle. Studies have shown that CD26 can be targeted by small molecules, such as inhibitors, which can inhibit its activity and disrupt its regulation of the cell division cycle.

In addition to its role in the cell division cycle, CD26 has also been shown to play a role in the regulation of cellular processes that are not related to the cell division cycle. For example, studies have shown that CD26 can be involved in the regulation of cell adhesion, cell migration, and the production of modulators of the DNA damage response.

Potential Therapeutic Applications of CD26

CD26 has been identified as a potential drug target due to its unique structure and its involvement in the cell division cycle. Studies have shown that CD26 can be targeted by small molecules, such as inhibitors, which can inhibit its activity and disrupt its regulation of the cell division cycle.

One of the potential therapeutic applications of CD26 is as a treatment for cancer. Cancer is a disease that can be caused by the uncontrolled growth and division of cells.CD

Protein Name: Cell Division Cycle 26

Functions: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex

More Common Targets

CDC27 | CDC27P2 | CDC34 | CDC37 | CDC37L1 | CDC37P1 | CDC40 | CDC42 | CDC42BPA | CDC42BPB | CDC42BPG | CDC42EP1 | CDC42EP2 | CDC42EP3 | CDC42EP4 | CDC42EP5 | CDC42SE1 | CDC42SE2 | CDC45 | CDC5L | CDC5L complex | CDC6 | CDC7 | CDC73 | CDCA2 | CDCA3 | CDCA4 | CDCA4P3 | CDCA5 | CDCA7 | CDCA7L | CDCA8 | CDCP1 | CDCP2 | CDH1 | CDH10 | CDH11 | CDH12 | CDH13 | CDH13-AS2 | CDH15 | CDH16 | CDH17 | CDH18 | CDH19 | CDH2 | CDH20 | CDH22 | CDH23 | CDH24 | CDH26 | CDH3 | CDH4 | CDH5 | CDH6 | CDH7 | CDH8 | CDH9 | CDHR1 | CDHR18P | CDHR2 | CDHR3 | CDHR4 | CDHR5 | CDIN1 | CDIP1 | CDIPT | CDIPTOSP | CDK1 | CDK10 | CDK11A | CDK11B | CDK12 | CDK13 | CDK14 | CDK15 | CDK16 | CDK17 | CDK18 | CDK19 | CDK2 | CDK20 | CDK2AP1 | CDK2AP2 | CDK2AP2P2 | CDK2AP2P3 | CDK3 | CDK4 | CDK5 | CDK5R1 | CDK5R2 | CDK5RAP1 | CDK5RAP2 | CDK5RAP3 | CDK6 | CDK6-AS1 | CDK7 | CDK8 | CDK9 | CDKAL1