LINC00515: A Potential Drug Target and Biomarker (G282566)

Target Name: LINC00515

NCBI ID: G282566

Other Name(s): Long intergenic non-protein coding RNA 515 | long intergenic non-protein coding RNA 515 | C21orf71 | PRED21

LINC00515: A Potential Drug Target and Biomarker

Introduction

LINC00515 is a long intergenic non-protein coding RNA (lncRNA) with a length of approximately 212 nucleotides.1 It is located between the genes GAP100 and TCF7L1, which are part of the unexpected transcript (UEX) cluster, a group of non -coding RNAs that are involved in the regulation of gene expression.2 LINC00515 has been identified as a potential drug target and biomarker due to its unique expression patterns and functional insights into the cell biology of cancer.

Structure and Expression

The structure of LINC00515 is characterized by a single exon and a single intron, which are located upstream of the gene.3 The exon starts at position -228 and has a stop codon at position -224. The intron starts at position -230 and has a stop codon at position -227.4

Expression of LINC00515

LINC00515 has been shown to be expressed in various tissues and cell types, including human tissues, cancer cells, and primary brain cells.5 Its expression has been described as highly expressed in liver cells, breast cells, neuronal cells, fibroblasts, and Epithelial Cells. 6

LINC00515 has been shown to play a role in the regulation of gene expression by binding to specific DNA sequences.7 This interaction between LINC00515 and DNA has led to the identification of LINC00515 as a potential drug target.

Drug Target Potential

The potential drug target for LINC00515 is its unique expression pattern, which has been shown to be different from that of its nearest neighbors.8 LINC00515 has been shown to have a unique expression pattern in various tissues, which may indicate that it has a unique function .9

In addition, LINC00515 has been shown to have a high degree of expression in cancer cells, which may make it an attractive drug target for cancer treatment.10

Biomarker Potential

The identification of LINC00515 as a potential drug target and biomarker has been supported by its expression patterns in various tissues and cell types.11 LINC00515 has been shown to have a unique expression pattern in cancer cells, which may indicate that it plays a unique role in the regulation of cancer cell growth and progression.12

Conclusion

In conclusion, LINC00515 is a long intergenic non-protein coding RNA that has been identified as a potential drug target and biomarker due to its unique expression patterns and functional insights into the cell biology of cancer. Further research is needed to determine the full potential of LINC00515 as a drug target and biomarker.

Protein Name: Long Intergenic Non-protein Coding RNA 515

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