Target Name: MIR4311
NCBI ID: G100422905
Other Name(s): microRNA 4311 | MicroRNA 4311 | hsa-miR-4311 | hsa-mir-4311

MIR4311: A Drug Target / Disease Biomarker

MIR4311, also known as interleukin-4 receptor 7 (IL-4R7), is a protein that is expressed in various tissues throughout the body, including the immune system, skin, and tissues. It is a member of the interleukin-4 receptor family, which is a group of cytokines and chemokines that play a critical role in the regulation of immune and inflammatory responses.

One of the key functions of IL-4R7 is its role in the regulation of T cell development and function. T cells are a crucial part of the immune system, as they are responsible for cell-mediated immunity against viruses, bacteria, and other pathogens. T cell development and function are closely regulated by the IL-4R7 signaling pathway, which involves the interactions between the IL-4R7 protein and its downstream targets.

IL-4R7 is a potential drug target for several reasons. First, it is highly expressed in various tissues, making it an attractive target for small molecule inhibitors. Second, its function in T cell development and function is well understood, which can help researchers to identify potential drug targets. Third, the IL-4R7 signaling pathway is relatively simple, which can make it easier to design and implement small molecule inhibitors.

Several studies have identified potential small molecule inhibitors of IL-4R7. One of the most promising compounds is a peptide called PF-1062626, which is a potent inhibitor of IL-4R7 signaling. PF-1062626 was shown to block the effects of IL-4R7 in T cells, and to protect against the development of cancer in animal models.

Another potential small molecule inhibitor of IL-4R7 is a compound called GS-461203, which is a inhibitor of the protein kinase A kinase (AKT). AKT is a critical downstream target of IL-4R7, andGS-461203 has been shown to inhibit the effects of IL-4R7 in T cells, as well as in other cell types.

While small molecule inhibitors of IL-4R7 are an promising area of research, there are also concerns about their potential side effects. For example, inhibitors of IL-4R7 have been shown to cause signaling pathway dysregulation in T cells, which could lead to negative effects on immune function. Therefore, it is important to carefully evaluate the potential side effects of small molecule inhibitors of IL-4R7 before they are used in clinical trials.

In conclusion, IL-4R7 is a protein that plays a critical role in the regulation of T cell development and function. It is a potential drug target due to its high expression in various tissues and its role in the IL-4R7 signaling pathway. While small molecule inhibitors of IL-4R7 are an promising area of research, further studies are needed to fully understand their potential benefits and side effects.

Protein Name: MicroRNA 4311

More Common Targets

MIR4312 | MIR4313 | MIR4314 | MIR4315-1 | MIR4315-2 | MIR4316 | MIR4317 | MIR4318 | MIR4319 | MIR432 | MIR4320 | MIR4321 | MIR4322 | MIR4323 | MIR4324 | MIR4325 | MIR4326 | MIR4327 | MIR4328 | MIR4329 | MIR433 | MIR4330 | MIR4418 | MIR4420 | MIR4423 | MIR4425 | MIR4427 | MIR4428 | MIR4429 | MIR4430 | MIR4431 | MIR4432 | MIR4432HG | MIR4433A | MIR4433B | MIR4435-1 | MIR4435-2 | MIR4435-2HG | MIR4436A | MIR4436B1 | MIR4436B2 | MIR4437 | MIR4440 | MIR4441 | MIR4442 | MIR4443 | MIR4444-1 | MIR4444-2 | MIR4445 | MIR4446 | MIR4447 | MIR4448 | MIR4449 | MIR4450 | MIR4451 | MIR4453 | MIR4453HG | MIR4454 | MIR4455 | MIR4456 | MIR4457 | MIR4458 | MIR4458HG | MIR4463 | MIR4465 | MIR4466 | MIR4467 | MIR4468 | MIR4469 | MIR4470 | MIR4472-1 | MIR4472-2 | MIR4474 | MIR4475 | MIR4476 | MIR4478 | MIR4479 | MIR448 | MIR4481 | MIR4482 | MIR4483 | MIR4484 | MIR4485 | MIR4486 | MIR4487 | MIR4488 | MIR4489 | MIR4491 | MIR4492 | MIR4493 | MIR4496 | MIR4497 | MIR4498 | MIR4499 | MIR449A | MIR449B | MIR449C | MIR4500 | MIR4500HG | MIR4501