LINC01973: A Potential Drug Target and Biomarker (G400624)

Target Name: LINC01973

NCBI ID: G400624

Other Name(s): Long intergenic non-protein coding RNA 1973 | long intergenic non-protein coding RNA 1973

LINC01973: A Potential Drug Target and Biomarker

Introduction

LINC01973 is a long intergenic non-protein coding RNA (lncRNA) that has been identified using transcriptome sequencing experiments. This RNA is different from traditional proteins in that it is not made by translation of mRNA, but instead is derived from genomic DNA. LINC01973 has has been shown to play a role in various cellular processes, including cell adhesion, migration, and invasion. Its function and regulation are still poorly understood, but its potential as a drug target or biomarker make it an attractive target for further research.

Drug Target Potential

LINC01973 has been shown to interact with several protein tyrosine kinases, including Src,FAK, and PDGFR. These interactions suggest that LINC01973 could be a potential drug target for cancer treatment. LINC01973 has also been shown to play a role in the regulation of cell adhesion. , which is a critical process for the maintenance of cancer stem cells. Therefore, small molecules that can inhibit LINC01973-PDGFR interactions may be useful for cancer treatment.

Biomarker Potential

LINC01973 has also been shown to be regulated by several factors, including E2F1,p63, and NF-kappa-B. These factors have been shown to play a role in the regulation of cellular processes such as cell growth, apoptosis, and angiogenesis. Therefore, small molecules that can modulate these factors may be useful for the development of biomarkers for cancer diagnosis and treatment.

Expression and Regulation

LINC01973 is a highly expressed gene in various tissues, including brain, heart, and pancreas. Its expression is regulated by several factors, including E2F1,p63, and NF-kappa-B. E2F1, a transcription factor that plays a role in the regulation of cell Cycle progression, has been shown to promote LINC01973 expression in various cell types. p63, a negative regulator of the tyrosine kinase kinase A3, has also been shown to regulate LINC01973 expression in pancreatic cancer cells. NF-kappa-B, a transcription factor that plays a role in the regulation of inflammation and cellular signaling, has also been shown to regulate LINC01973 expression in various cell types.

Function and Interaction

LINC01973 has been shown to play a role in several cellular processes, including cell adhesion, migration, and invasion. Its function and regulation are still poorly understood, but its potential as a drug target or biomarker make it an attractive target for further research.

Conclusion

LINC01973 is a long intergenic non-protein coding RNA that has been identified using transcriptome sequencing experiments. Its function and regulation are still poorly understood, but its potential as a drug target or biomarker make it an attractive target for further research. Further studies are needed to determine the role of LINC01973 in cellular processes and its potential as a drug target or biomarker.

Protein Name: Long Intergenic Non-protein Coding RNA 1973

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