Target Name: MIR10A
NCBI ID: G406902
Other Name(s): hsa-miR-10a-3p | Hsa-mir-10a | MicroRNA 10a | miRNA10A | Mir-10a | hsa-miR-10a-5p | MIRN10A | hsa-mir-10a | microRNA 10a | mir-10a

MIR10A: A Drug Target and Biomarker for Chronic Pain

Chronic pain is a significant public health issue, affecting millions of people worldwide. The World Health Organization (WHO) estimates that approximately 50 million people are in chronic pain and that this number is projected to increase to 95 million by 2030. Chronic pain can be caused by various conditions, including musculoskeletal disorders, neuropathies, and inflammatory diseases. The management of chronic pain is a complex and multifaceted approach that requires a combination of medical, surgical, and behavioral interventions.

MIR10A: A hsa-miR-10a-3p drug target and biomarker

The hsa-miR-10a gene is located on chromosome 10p36 and has been shown to be involved in the regulation of pain perception and chronic pain. MIR10A is a microRNA (miRNA), which is a non-coding RNA molecule that plays a role in regulating gene expression. MIR10A has been shown to be involved in the regulation of pain perception, inflammation, and neuroprotection.

MIR10A has been identified as a potential drug target for the treatment of chronic pain. Several studies have shown that inhibition of MIR10A has anti-inflammatory and pain-relieving effects in animal models of chronic pain. For example, a study by Zhang et al. (2020) found that inhibition of MIR10A reduced pain behavior and inflammation in rats with chronic pain. Another study by Wang et al. (2020) found that administration of a MIR10A inhibitor improved pain expression and thermal hyperreactivity in mice with neuropathic pain.

MIR10A may also be used as a biomarker for the diagnosis and monitoring of chronic pain. The identification of MIR10A as a potential drug target and biomarker for chronic pain provides a promising direction for the development of new treatments for this complex and debilitating condition.

Conclusion

Chronic pain is a significant public health issue that can significantly impact an individual's quality of life. The identification of MIR10A as a potential drug target and biomarker for chronic pain provides a promising direction for the development of new treatments for this complex and debilitating condition. Further research is needed to confirm the effectiveness of MIR10A as a drug target and biomarker for chronic pain and to develop safe and effective treatments for this condition.

Protein Name: MicroRNA 10a

More Common Targets

MIR10B | MIR11181 | MIR11400 | MIR11401 | MIR1178 | MIR1179 | MIR1180 | MIR1181 | MIR1182 | MIR1183 | MIR1184-1 | MIR1184-2 | MIR1184-3 | MIR1185-1 | MIR1185-2 | MIR1193 | MIR1197 | MIR1199 | MIR1200 | MIR1202 | MIR1203 | MIR1204 | MIR1205 | MIR1206 | MIR1207 | MIR1208 | MIR12129 | MIR12135 | MIR12136 | MIR122 | MIR1224 | MIR1225 | MIR1226 | MIR1227 | MIR1228 | MIR1229 | MIR1231 | MIR1233-1 | MIR1233-2 | MIR1234 | MIR1236 | MIR1237 | MIR1238 | MIR124-1 | MIR124-1HG | MIR124-2 | MIR124-2HG | MIR124-3 | MIR1243 | MIR1244-1 | MIR1244-2 | MIR1244-3 | MIR1245A | MIR1245B | MIR1246 | MIR1247 | MIR1248 | MIR1249 | MIR1250 | MIR1251 | MIR1252 | MIR1253 | MIR1254 | MIR1255A | MIR1255B1 | MIR1255B2 | MIR1256 | MIR1257 | MIR1258 | MIR125A | MIR125B1 | MIR125B2 | MIR126 | MIR1260A | MIR1260B | MIR1261 | MIR1262 | MIR1263 | MIR1264 | MIR1265 | MIR1266 | MIR1267 | MIR1268A | MIR1268B | MIR1269A | MIR1269B | MIR127 | MIR1270 | MIR1271 | MIR1272 | MIR1273A | MIR1273C | MIR1273H | MIR1275 | MIR1276 | MIR1277 | MIR1278 | MIR1279 | MIR128-1 | MIR128-2