Target Name: MIR181B2
NCBI ID: G406956
Other Name(s): MicroRNA 181b-2 | hsa-miR-181b-5p | hsa-miR-181b | MIRN181B2 | hsa-miR-181b-2-3p | mir-181b-2 | microRNA 181b-2 | hsa-mir-181b-2

MicroRNA 181b-2: Potential Drug Target Or Biomarker

MicroRNA (miRNA) 181b-2 is a non-coding RNA molecule that plays a critical role in various biological processes in the human body. It is a part of a family of miRNAs known as miR181, which are known to have a significant impact on post-transcriptional gene regulation. In this article, we will discuss the research on miR181b-2 and its potential as a drug target or biomarker.

The miR181b-2 gene

The miR181b-2 gene is located on chromosome 16 at position 614.2 and has a length of 21 nucleotides. It is a part of the miR181 gene family, which consists of 181 miRNAs that have been identified so far. All of these miRNAs have a conserved structure, which consists of a hairpin loop and a 26-base pair non-coding RNA molecule.

Function of miR181b-2

Studies have shown that miR181b-2 plays a critical role in the regulation of various biological processes, including cell growth, apoptosis, and inflammation. One of the most well-studied functions of miR181b-2 is its role in cell apoptosis. miR181b-2 has been shown to promote the apoptosis of cancer cells by targeting various cellular signaling pathways, including the TGF-β pathway.

In addition to its role in cell apoptosis, miR181b-2 has also been shown to play a critical role in the regulation of cell cycle progression. It has been shown to inhibit the G1 cell cycle by reducing the amount of G1-S2 protein produced. This suggests that miR181b-2 may have potential as a drug target for cancer treatment.

Potential as a drug target

The potential of miR181b-2 as a drug target is based on its role in the regulation of various biological processes, including cell growth, apoptosis, and inflammation. miR181b-2 has been shown to promote the apoptosis of cancer cells by targeting various cellular signaling pathways, including the TGF-β pathway. This suggests that targeting miR181b-2 may be an effective way to treat cancer.

In addition to its role in cancer treatment, miR181b-2 may also have potential as a biomarker for cancer diagnosis. The expression of miR181b-2 has been shown to be regulated by various factors, including cancer status, tissue type, and treatment status. This suggests that miR181b-2 may be a useful biomarker for cancer diagnosis and monitoring.

Potential as a biomarker

The potential of miR181b-2 as a biomarker for cancer diagnosis is based on its role in the regulation of various biological processes, including cell growth, apoptosis, and inflammation. miR181b-2 has been shown to promote the apoptosis of cancer cells by targeting various cellular signaling pathways, including the TGF-β pathway. This suggests that targeting miR181b-2 may be an effective way to diagnose cancer.

In addition to its potential as a drug target, miR181b-2 may also have potential as a biomarker for cancer diagnosis. The expression of miR181b-2 has been shown to be regulated by various factors, including cancer status, tissue type, and treatment status. This suggests that miR181b-2 may be a useful biomarker for cancer diagnosis and monitoring.

Conclusion

In conclusion, miR181b-2 is a non-coding RNA molecule that plays a critical role in various biological processes in the human body. Its functions include cell growth, apoptosis, and inflammation. The potential of miR181b-2 as a drug target or biomarker is based on its role in these processes and its regulation by various cellular signaling pathways. Further research is needed to fully understand the role of miR181b-2 in the regulation of various biological processes and its potential as a drug

Protein Name: MicroRNA 181b-2

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MIR181C | MIR181D | MIR182 | MIR1825 | MIR1827 | MIR183 | MIR184 | MIR185 | MIR186 | MIR187 | MIR188 | MIR18A | MIR18B | MIR1908 | MIR1909 | MIR190A | MIR190B | MIR191 | MIR1910 | MIR1911 | MIR1912 | MIR1913 | MIR1914 | MIR1915 | MIR1915HG | MIR192 | MIR193A | MIR193B | MIR193BHG | MIR194-1 | MIR194-2 | MIR194-2HG | MIR195 | MIR196A1 | MIR196A2 | MIR196B | MIR197 | MIR1972-1 | MIR1972-2 | MIR1973 | MIR1976 | MIR198 | MIR199A1 | MIR199A2 | MIR199B | MIR19A | MIR19B1 | MIR19B2 | MIR200A | MIR200B | MIR200C | MIR200CHG | MIR202 | MIR202HG | MIR203A | MIR203B | MIR204 | MIR205 | MIR2052 | MIR2052HG | MIR2053 | MIR2054 | MIR205HG | MIR206 | MIR208A | MIR208B | MIR20A | MIR20B | MIR21 | MIR210 | MIR210HG | MIR211 | MIR2110 | MIR2113 | MIR2114 | MIR2115 | MIR2116 | MIR2117 | MIR212 | MIR214 | MIR215 | MIR216A | MIR216B | MIR217 | MIR217HG | MIR218-1 | MIR218-2 | MIR219A1 | MIR219A2 | MIR219B | MIR22 | MIR221 | MIR222 | MIR223 | MIR224 | MIR2276 | MIR2277 | MIR2278 | MIR22HG | MIR2355