MECP2: A Protein Implicated in Cell Signaling Pathways (G4204)

Target Name: MECP2

NCBI ID: G4204

MECP2: A Protein Implicated in Cell Signaling Pathways

MECP2 (MECP2B) is a protein that is expressed in various tissues of the body, including the brain, heart, and gastrointestinal tract. It is a member of the MECP (Mammalian Endoplasmic Reticulum) family, which includes proteins that play a critical role in the regulation of intracellular signaling pathways.

One of the functions of MECP2 is to interact with the protein kinase AFRP1, which is a key regulator of the TGF-β pathway. The TGF-β pathway is a complex signaling pathway that is involved in the regulation of cell growth, differentiation, and survival. MECP2 has been shown to play a role in the regulation of TGF-β pathway-related processes, including the regulation of cell proliferation and the modulation of cellular signaling pathways.

MECP2 has also been shown to interact with the protein Fyn, which is a critical regulator of the Fc portion of integrins, a protein that plays a role in cell-cell adhesion. The Fc portion of integrins is involved in the regulation of cellular adhesion, and MECP2 has been shown to be involved in the regulation of this process.

In addition to its role in the regulation of TGF-β and Fc integrins, MECP2 has also been shown to play a role in the regulation of cellular signaling pathways that are involved in the regulation of cell survival. For example, MECP2 has been shown to play a role in the regulation of the PI3K/AKT signaling pathway, which is involved in the regulation of cellular signaling pathways that are involved in cell survival.

MECP2 has also been shown to interact with the protein SLC30A8, which is a regulator of the Na+/K+ATPase, a protein that is involved in the regulation of intracellular signaling pathways. signaling pathways, including the regulation of cell survival, and MECP2 has been shown to play a role in the regulation of this process.

MECP2 has also been shown to interact with the protein Pyh, which is a regulator of the Pyh/TAZ-dependent kinase pathway, a signaling pathway that is involved in the regulation of cell survival.

In conclusion, MECP2 is a protein that has been shown to play a critical role in the regulation of various cellular signaling pathways that are involved in the regulation of cell growth, differentiation, and survival. The MECP2 protein is a potential drug target and may be a biomarker for various diseases, including cancer. Further research is needed to fully understand the role of MECP2 in cellular signaling pathways and its potential as a drug target.

Protein Name: Methyl-CpG Binding Protein 2

Functions: Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC)

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