SLC6A20: A Drug Target / Disease Biomarker (G54716)

Target Name: SLC6A20

NCBI ID: G54716

SLC6A20: A Drug Target / Disease Biomarker

SLC6A20 is a gene that encodes a protein known as solute carrier family 6 member 20. The protein encoded by this gene is a member of the SLC6A family, which is a family of transmembrane proteins that play an important role in the transport of various molecules across cell membranes. SLC6A20 is expressed in many different tissues and cells in the body, including the brain, heart, kidneys, and liver.

One of the key functions of SLC6A20 is its role in the transport of drugs and other substances across cell membranes. This protein is expressed in high levels in the brain, and it has been shown to play a role in the uptake and retention of drugs such as morphine and quetiapine.

In addition to its role in drug transport, SLC6A20 is also involved in the regulation of various signaling pathways that are important for brain function. For example, this protein has been shown to play a role in the regulation of neurotransmitter release from synapses, which is important for the function of the brain.

SLC6A20 is also expressed in many other tissues and cells in the body, including the heart, kidneys, and liver. This makes it an attractive target for researchers who are interested in developing new treatments for a variety of diseases.

In conclusion, SLC6A20 is a protein that has important roles in drug transport and the regulation of various signaling pathways in the brain. As a drug target or biomarker, SLC6A20 has the potential to be a valuable tool for the development of new treatments for a variety of diseases.

Protein Name: Solute Carrier Family 6 Member 20

Functions: Mediates the Na(+)- and Cl(-)-dependent uptake of imino acids such as L-proline, N-methyl-L-proline and pipecolate as well as N-methylated amino acids (PubMed:15632147, PubMed:19033659, PubMed:33428810). Also transports glycine, regulates proline and glycine homeostasis in the brain playing a role in the modulation of NMDAR currents (PubMed:33428810)

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