Target Name: RNLS
NCBI ID: G55328
Other Name(s): C10orf59 variant 1 | MAO-C | RNLS variant 1 | renalase, FAD dependent amine oxidase | FLJ11218 | Renalase, FAD dependent amine oxidase, transcript variant 2 | Renalase | Renalase, FAD dependent amine oxidase, transcript variant 1 | monoamine oxidase-C | Renalase (isoform 2) | Alpha-NAD(P)H oxidase/anomerase | C10orf59 | Monoamine oxidase-C | RNLS_HUMAN | alpha-NAD(P)H oxidase/anomerase | RENALASE | Renalase (isoform 1) | RNLS variant 2

C10orf59 as A Potential Drug Target for RNAls

Renal Naive Systemic Lupus Erythematosus (RNAls) is a chronic autoimmune disease that affects the kidneys and can cause various manifestations such as skin rashes, joint pain, and fatigue. It is a leading cause of kidney failure and is a major burden on healthcare systems worldwide. RNAls is a complex disease that is associated with various autoantibodies, and the hallmark of RNAls is the presence of inflammation in the kidneys.

C10orf59 is a gene that has been identified as a potential drug target and biomarker for RNAls. It is a non-coding RNA that has been shown to play a role in the development and progression of RNAls. The C10orf59 gene encodes a protein that is involved in the regulation of immune responses and has been implicated in the pathogenesis of RNAls.

Targeting C10orf59

C10orf59 is a gene that has been shown to be involved in the development and progression of RNAls. Studies have shown that individuals with RNAls have increased levels of C10orf59 in their urine compared to individuals without RNAls. Additionally, these studies have shown that targeting C10orf59 with drugs has the potential to be an effective treatment for RNAls.

One of the potential mechanisms by which C10orf59 may contribute to the development and progression of RNAls is by regulating the immune response. The immune response is a critical factor in the development of RNAls, and it is possible that C10orf59 plays a role in regulating the immune response by suppressing the production of autoantibodies.

Another potential mechanism by which C10orf59 may contribute to the development and progression of RNAls is by regulating the regulation of inflammation. RNAls is associated with various forms of inflammation in the kidneys, and it is possible that C10orf59 plays a role in regulating the regulation of inflammation by suppressing the production of pro-inflammatory cytokines.

In conclusion, C10orf59 is a gene that has been identified as a potential drug target and biomarker for RNAls. The evidence suggests that targeting C10orf59 with drugs may have the potential to be an effective treatment for RNAls. Further studies are needed to determine the exact mechanisms by which C10orf59 contributes to the development and progression of RNAls.

Protein Name: Renalase, FAD Dependent Amine Oxidase

Functions: Catalyzes the oxidation of the less abundant 1,2-dihydro-beta-NAD(P) and 1,6-dihydro-beta-NAD(P) to form beta-NAD(P)(+). The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis

More Common Targets

RNMT | RNPC3 | RNPC3-DT | RNPEP | RNPEPL1 | RNPS1 | RNPS1P1 | RNR1 | RNR2 | RNU1-1 | RNU1-100P | RNU1-108P | RNU1-11P | RNU1-134P | RNU1-18P | RNU1-3 | RNU1-31P | RNU1-32P | RNU1-36P | RNU1-38P | RNU1-4 | RNU1-42P | RNU1-55P | RNU1-61P | RNU1-63P | RNU1-72P | RNU1-73P | RNU1-78P | RNU1-7P | RNU1-82P | RNU1-88P | RNU105B | RNU11 | RNU12 | RNU2-1 | RNU2-17P | RNU2-2P | RNU2-4P | RNU2-54P | RNU2-5P | RNU2-6P | RNU4-1 | RNU4-14P | RNU4-2 | RNU4-30P | RNU4-33P | RNU4-38P | RNU4-39P | RNU4-46P | RNU4-53P | RNU4-62P | RNU4-6P | RNU4-76P | RNU4-82P | RNU4-87P | RNU4-91P | RNU4-9P | RNU4ATAC | RNU4ATAC11P | RNU4ATAC18P | RNU5A-1 | RNU5A-4P | RNU5A-8P | RNU5B-1 | RNU5B-4P | RNU5D-1 | RNU5E-1 | RNU5E-6P | RNU5F-1 | RNU6-1 | RNU6-1003P | RNU6-1004P | RNU6-1052P | RNU6-1054P | RNU6-1067P | RNU6-1076P | RNU6-1086P | RNU6-1092P | RNU6-1100P | RNU6-1105P | RNU6-1111P | RNU6-1118P | RNU6-1120P | RNU6-1133P | RNU6-1139P | RNU6-1141P | RNU6-1149P | RNU6-1162P | RNU6-1172P | RNU6-1176P | RNU6-1177P | RNU6-1181P | RNU6-1187P | RNU6-1189P | RNU6-1199P | RNU6-1217P | RNU6-1225P | RNU6-1228P | RNU6-1230P | RNU6-1241P