ACTR10: A Potential Drug Target and Biomarker for Actin-Related Protein 10

Target Name: ACTR10

NCBI ID: G55860

ACTR10: A Potential Drug Target and Biomarker for Actin-Related Protein 10

Actin-related protein 10 (ACTR10) is a protein that plays a crucial role in the regulation of actin dynamics and dynamics of actin-associated proteins (AAPs) in eukaryotic cells. It is composed of 126 amino acid residues and has a calculated molecular weight of 13.9 kDa. ACTR10 functions as a negative regulator of the protein kinase Cdc6, which is involved in actin dynamics and the regulation of cell adhesion. The dysfunction of ACTR10 has been implicated in various diseases, including cancer, neurodegenerative diseases, and developmental disorders. As a result, targeting ACTR10 has become an attractive research topic in the field of molecular biology and has the potential to reveal new therapeutic strategies.

Drug Target Potential

ACTR10 has been identified as a potential drug target due to its critical role in the regulation of actin dynamics and the control of cell adhesion. The dysfunction of ACTR10 has been associated with the development and progression of various diseases, including cancer, neurodegenerative diseases, and developmental disorders. Therefore, inhibition of ACTR10 has been proposed as a potential therapeutic approach for treating these diseases.

One of the potential benefits of targeting ACTR10 is its potential to disrupt the regulation of actin dynamics by Cdc6. This disruption could lead to an increase in the activity of other proteins that are involved in actin dynamics, such as the protein F-actinin. This increase in the activity of these proteins could result in the formation of actin stress fibers, which are thought to contribute to the development of neurodegenerative diseases. Additionally, ACTR10 has been shown to play a role in the regulation of cell adhesion, and inhibition of its function could lead to the formation of cell aggregates that are involved in the development of various diseases, including cancer.

Biomarker Potential

In addition to its potential as a drug target, ACTR10 has also been identified as a potential biomarker for various diseases. The dysfunction of ACTR10 has been associated with the development and progression of cancer, neurodegenerative diseases, and developmental disorders. Therefore, the levels of ACTR10 have been proposed as a potential biomarker for these diseases.

One approach to measuring the levels of ACTR10 is to use techniques such as Western blotting or immunofluorescence. These techniques can be used to detect the expression of ACTR10 in a variety of cellular samples, including tissues, cells, and cell culture dishes. The levels of ACTR10 could then be quantified using techniques such as immunoprecipitation or mass spectrometry.

Another approach to measuring the levels of ACTR10 is to use it as a protein-interaction partner. This can be done by using yeast two-hybrid or protein fragment complementation assays to identify protein-interaction partners of ACTR10. The identification of protein-interaction partners of ACTR10 could provide insights into the mechanisms of its function and could be a potential lead for new therapeutic strategies.

Conclusion

In conclusion, ACTR10 is a protein that plays a crucial role in the regulation of actin dynamics and dynamics of actin-associated proteins in eukaryotic cells. Its dysfunction has been implicated in the development and progression of various diseases, including cancer, neurodegenerative diseases, and developmental disorders. As a result, targeting ACTR10 has become an attractive research topic in the field of molecular biology and has the potential to reveal new therapeutic strategies. Additionally, ACTR10 has also been identified as a potential biomarker for various diseases, which could be used to monitor disease progression and the effectiveness of therapeutic strategies. Further research is needed to fully understand the function of ACTR10 and its potential as a drug

Protein Name: Actin Related Protein 10

Functions: Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules

More Common Targets