SCAF1: A Protein Regulating Gene Expression and Protein Translation

Target Name: SCAF1

NCBI ID: G58506

SCAF1: A Protein Regulating Gene Expression and Protein Translation

SCAF1 (SFR19_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, heart, and kidneys. It is a member of the superfamily of RNA-binding proteins known as scaffold proteins, and it is involved in the regulation of gene expression and protein translation.

SCAF1 is a 21-kDa protein that consists of 191 amino acid residues. It has a characteristic Rossmann-fold structure that is commonly found in proteins that interact with RNA. This structure is responsible for the protein's ability to form a stable complex with RNA molecules, such as tRNAs and rRNAs.

SCAF1 is highly expressed in various tissues of the human body, including the brain, heart, and kidneys. It is also expressed in various cell types, including muscle, nerve, and epithelial cells. The protein is primarily localized to the cytoplasm of these cells, but it can also be found in the cell nucleus.

SCAF1 has been shown to play a role in the regulation of gene expression and protein translation. It has been shown to interact with various RNA molecules, including tRNAs, rRNAs, and microRNAs. SCAF1 has been shown to form a stable complex with tRNAs in the cytoplasm, and this interaction is required for tRNA processing and loading into the cytoplasm.

SCAF1 has also been shown to play a role in the regulation of cellular processes such as cell growth, apoptosis, and autophagy. It has been shown to be involved in the regulation of cell cycle progression, and it has been shown to play a role in the regulation of cell apoptosis.

SCAF1 is also a potential drug target in the treatment of various diseases. For example, it has been shown to be involved in the regulation of the immune response, and it has been shown to play a role in the regulation of inflammation. Therefore, SCAF1 may be a useful target for the development of new treatments for autoimmune diseases and other inflammatory disorders.

In conclusion, SCAF1 is a protein that is expressed in various tissues of the human body and is involved in the regulation of gene expression and protein translation. It has a characteristic Rossmann-fold structure that allows it to form a stable complex with RNA molecules, and it has been shown to play a role in the regulation of various cellular processes. As a result, SCAF1 may be a useful target for the development of new treatments for various diseases.

Protein Name: SR-related CTD Associated Factor 1

Functions: May function in pre-mRNA splicing

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