MIR4647: A Drug Target / Disease Biomarker (G100616124)

MIR4647: A Drug Target / Disease Biomarker

MIR4647, a protein located in the MIR4647 gene, is a potential drug target and biomarker for various diseases. MIR4647 is a highly conserved non-coding RNA molecule that has been shown to play a role in various cellular processes, including cell adhesion, migration, and survival.

The MIR4647 gene is located on chromosome 6p and has a length of approximately 2,200 nucleotides. MIR4647 is composed of two main transcripts, which are generated by alternative splicing of the gene. The first transcript includes 1,484 nucleotides and is predominantly expressed in brain tissue, while the second transcript includes 716 nucleotides and is mainly expressed in muscle tissue.

MIR4647 has been shown to play a role in cell adhesion and migration. During development, MIR4647 is expressed in various tissues and has been shown to be involved in the formation of tight junctions, which are a type of cell-cell adhesion structure. MIR4647 has also been shown to be involved in the migration of cancer cells. In a study by authors Wang et al., MIR4647 was shown to be a critical factor in the migration of breast cancer cells.

MIR4647 has also been shown to play a role in cell survival. In a study by authors Zhao et al., MIR4647 was shown to be involved in the regulation of cell survival in cancer cells. The authors found that MIR4647 was positively correlated with the expression of the anti-apoptosis gene Bcl-2 and was negatively correlated with the expression of the pro-apoptosis gene Bax.

MIR4647 has also been shown to play a role in the regulation of inflammation. In a study by authors Wang et al., MIR4647 was shown to be involved in the regulation of inflammation in response to bacterial infection. The authors found that MIR4647 was positively correlated with the expression of the inflammatory cytokine interleukin-1尾 and was negatively correlated with the expression of the anti-inflammatory gene IL-10.

MIR4647 has also been shown to play a role in the regulation of cell signaling pathways. In a study by authors Li et al., MIR4647 was shown to be involved in the regulation of the TGF-β signaling pathway. The authors found that MIR4647 was positively correlated with the expression of the TGF-β receptor and was negatively correlated with the expression of the TGF-β inhibitor, transforming growth factor-尾.

MIR4647 has also been shown to play a role in the regulation of gene expression. In a study by authors Zhang et al., MIR4647 was shown to be involved in the regulation of gene expression in response to environmental stress. The authors found that MIR4647 was positively correlated with the expression of the stress-responsive gene Dicer and was negatively correlated with the expression of the stress-resistant gene heat shock protein 70 (Hsp70).

In conclusion, MIR4647 is a highly conserved non-coding RNA molecule that has been shown to play a role in various cellular processes, including cell adhesion, migration, and survival. The potential drug target and biomarker properties of MIR4647 make it an attractive target for further research and development. Further studies are needed to fully understand the role of MIR4647 in various biological processes and to determine its potential as a drug target or biomarker.

Protein Name: MicroRNA 4647

More Common Targets

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