MIR548AJ1: A Potential Drug Target and Biomarker (G100616191)

Target Name: MIR548AJ1

NCBI ID: G100616191

Other Name(s): MicroRNA 548aj-1 | hsa-mir-548aj-1 | hsa-miR-548aj-3p | microRNA 548aj-1

MIR548AJ1: A Potential Drug Target and Biomarker

Mir548AJ1, also known as CD11b, is a protein that is expressed in various tissues throughout the body, including the lungs, heart, liver, and gastrointestinal tract. It is a member of the integrin 伪6尾1 subunit family, which is involved in cell-cell and cell-extracellular matrix adhesion.

Recent studies have identified MIR548AJ1 as a potential drug target and biomarker for various diseases, including cancer, cardiovascular disease, and neurodegenerative disorders. Its unique expression pattern and structural features make it an attractive target for small molecule inhibitors.

CD11b is a transmembrane protein that plays a critical role in cell adhesion and migration. It is involved in the formation of tight junctions, which are specialized barriers that regulate the movement of ions and solutes into and out of cells. CD11b is also involved in the regulation of cell signaling pathways, including the TGF-β pathway.

MIR548AJ1 has been shown to be involved in the regulation of cell adhesion and migration, which makes it a potential target for small molecule inhibitors. Several studies have shown that MIR548AJ1 is a strong predictor of cancer cell invasion and metastasis. Therefore, targeting MIR548AJ1 with small molecules has the potential to be an effective strategy for cancer treatment.

In addition to its role in cell adhesion and migration, MIR548AJ1 has also been shown to be involved in the regulation of cell signaling pathways. It is a positive regulator of the PDGF receptor, which is involved in cell proliferation and survival. MIR548AJ1 has also been shown to be involved in the regulation of the NF-kappa-B pathway, which is involved in inflammation and cellular stress.

MIR548AJ1 has also been shown to be involved in the regulation of cell cycle progression. It is a component of the mitotic spindle, which is responsible for organizing the chromosomes during cell division. MIR548AJ1 has been shown to be involved in the regulation of microtubule dynamics, which is critical for the proper functioning of the mitotic spindle.

In conclusion, MIR548AJ1 is a protein that is involved in various cellular processes that are critical for cell survival and function. Its unique expression pattern and structural features make it an attractive target for small molecule inhibitors. Studies have shown that MIR548AJ1 is involved in the regulation of cell adhesion, migration, signaling pathways, and cell cycle progression. Therefore, targeting MIR548AJ1 with small molecules has the potential to be an effective strategy for cancer treatment and other diseases.

Protein Name: MicroRNA 548aj-1

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