TPM2: A Protein Potential Drug Target and Biomarker (G7169)

Target Name: TPM2

NCBI ID: G7169

TPM2: A Protein Potential Drug Target and Biomarker

Tropomyosin beta chain, also known as TPM2, is a protein that is expressed in most tissues of the body. It plays a critical role in cell signaling, particularly in the regulation of muscle contractions. TPM2 has also been identified as a potential drug target and biomarker for several diseases, including heart failure, hypertension, and cancer.

The TPM2 protein is composed of 256 amino acids and has a molecular weight of 31.1 kDa. It is a key component of the microtubules, which are the protein structures that organize the cytoskeleton in eukaryotic cells. TPM2 is responsible for the regulation of the speed and stability of microtubules, which is critical for the proper functioning of the cell.

TPM2 has been shown to play a role in the regulation of muscle contractions. It is expressed in the muscle fibers and is involved in the regulation of muscle contraction and relaxation. TPM2 has been shown to interact with the protein myosin, which is responsible for the synthesis of the myosin heads that are responsible for the force of the muscle contractions.

In addition to its role in muscle physiology, TPM2 has also been shown to be involved in several diseases, including heart failure, hypertension, and cancer. Heart failure is a condition in which the heart is unable to pump enough blood to meet the body's needs. TPM2 has been shown to be expressed in the hearts of individuals with heart failure and has been shown to play a role in the regulation of heart contractions.

Hypertension, or high blood pressure, is a condition in which the blood pressure is above normal. TPM2 has been shown to be involved in the regulation of blood pressure and has been shown to play a role in the development of hypertension.

TPM2 has also been shown to be involved in the regulation of cancer cell growth. It has been shown to be expressed in the cells of individuals with various types of cancer and has been shown to play a role in the regulation of cell growth and the development of cancer.

Due to its involvement in several diseases and its potential as a drug target, TPM2 has become a focus of research in recent years. Researchers have been interested in identifying small molecules that can interact with TPM2 and modulate its activity. This has led to the development of a new class of drugs called microsphere-based delivery systems, which can be used to deliver small molecules to TPM2-expressing cells.

In conclusion, TPM2 is a protein that is expressed in most tissues of the body and plays a critical role in cell signaling, particularly in the regulation of muscle contractions. It has also been identified as a potential drug target and biomarker for several diseases, including heart failure, hypertension, and cancer. Further research is needed to fully understand the role of TPM2 in these diseases and to develop new treatments based on its properties.

Protein Name: Tropomyosin 2

Functions: Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. The non-muscle isoform may have a role in agonist-mediated receptor internalization

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