LINC01087: A Long Intergenic Non-Protein-Coding RNA as a Drug Target or Biomarker

Target Name: LINC01087

NCBI ID: G101927994

Other Name(s): long intergenic non-protein coding RNA 1087 | Long intergenic non-protein coding RNA 1087

LINC01087: A Long Intergenic Non-Protein-Coding RNA as a Drug Target or Biomarker

LINC01087 is a long intergenic non-protein-coding RNA (lncRNA) that has been identified in various organisms, including humans. It has a unique feature of having a conserved domain that is similar to that of known non-coding RNAs (ncRNAs), which are involved in various cellular processes. Despite its unique structural feature, LINC01087 has not been well studied, and its functions and potential uses are not well understood.

In this article, we will explore the characterization of LINC01087 and its potential uses as a drug target or biomarker.

Characterization of LINC01087

LINC01087 is a 21.1-kb RNA molecule that contains 19 exons and 1 intron. It has a conserved domain that is similar to that of known non-coding RNAs. The conserved domain is located at the start of the RNA molecule and consists of 129 amino acid residues.

The conserved domain of LINC01087 contains several conserved motifs, such as a GCA repeat, a TCA repeat, and a stem-loop structure. These motifs are commonly found in non-coding RNAs and are involved in the formation of RNA structures that have various functions in cellular processes.

Expression and localization

LINC01087 is expressed in various tissues and cells in the body, including brain, heart, and muscle. It is primarily expressed in the brain, where it is found at relatively high levels. LINC01087 is also expressed in other tissues, including heart and muscle, at relatively low levels.

LINC01087 is localized to specific cellular compartments in the brain. It is predominantly expressed in the peri-synaptic zone, which is the area between the terminal axons of neurons and the dendrites of their astrocytes. LINC01087 is also expressed in the axonal zone, which is the area between the terminal axons of neurons and the cell body, and in the cytoplasm, which is the fluid-filled space around the cells.

Function and potential uses

The functions of LINC01087 are not well understood, but it is possible that it plays a role in various cellular processes in the brain. LINC01087 is expressed in the peri-synaptic zone, which is the area between the terminal axons of neurons and the dendrites of their astrocytes. This suggests that it may be involved in the regulation of synaptic transmission, which is critical for the function of the brain.

LINC01087 is also expressed in the axonal zone, which is the area between the terminal axons of neurons and the cell body. This suggests that it may be involved in the regulation of axonal transport, which is critical for the development and maintenance of neural circuits.

In addition to its potential role in cellular processes in the brain, LINC01087 may also have potential uses as a drug target or biomarker. Its unique conserved domain and its expression in specific cellular compartments in the brain suggest that it may be a good candidate for manipulation to achieve specific cellular functions.

Conclusion

In this article, we have characterized LINC01087, a long intergenic non-protein-coding RNA, and its potential uses as a drug target or biomarker. LINC01087 is expressed in various tissues and cells in the body, including the brain, and is primarily expressed in the peri-synaptic zone. It contains conserved motifs that are commonly found in non-coding RNAs and is localized to specific cellular compartments in the brain. Further studies are needed to determine its functions and potential uses.

Protein Name: Long Intergenic Non-protein Coding RNA 1087

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