LINC02214: A Long Intergenic Non-Protein Coding RNA as a Drug Target or Biomarker

Target Name: LINC02214

NCBI ID: G102467223

Other Name(s): Long intergenic non-protein coding RNA 2214 | long intergenic non-protein coding RNA 2214

LINC02214: A Long Intergenic Non-Protein Coding RNA as a Drug Target or Biomarker

LINC02214 is a long non-coding RNA (lncRNA) molecule that has been identified using RNA sequencing (RNA-seq) data. It is located between the intron-exon boundaries of genes 14 and 15 of the X chromosome in humans, and its full name is long intergenic non-protein coding RNA 2214.

Expression of LINC02214

LINC02214 is a highly expressed gene in human tissues, with the highest expression levels observed in the brain, followed by the heart, liver, and muscle. It is also expressed in various cell types, including neurons, astrocytes, and macrophages.

Function of LINC02214

The function of LINC02214 is not well understood, but its expression patterns suggest that it may be involved in various cellular processes. One potential function of LINC02214 is as a drug target, as it has been shown to be highly expressed in cancer cells and may be a promising target for small molecules or antibodies.

Drug Target Potential

The drug targeting potential of LINC02214 is based on its expression patterns in cancer cells. Cancer cells are known to have altered levels of gene expression, and LINC02214 has been shown to be highly expressed in various types of cancer. This suggests that LINC02214 may be a promising drug target for cancer treatment.

Biomarker Potential

In addition to its potential as a drug target, LINC02214 may also be a useful biomarker for various diseases. For example, LINC02214 has been shown to be highly expressed in individuals with Alzheimer's disease, a progressive neurodegenerative disorder that is characterized by the accumulation of neurofibrillary tangles and beta-amyloid plaques in the brain.

Analysis of LINC02214

To further study the potential of LINC02214 as a drug target or biomarker, researchers have used various techniques to analyze its expression and function. One approach is to use RNA-seq data to identify its expression levels and quantify its expression. This has led to a detailed understanding of its expression patterns in various cell types and tissues.

Another approach is to use various assays to study its function, such as live cell imaging, RNA-mediated assays, and mass spectrometry. These assays have allowed researchers to determine the mechanisms of LINC02214's function and identify potential targets for drug intervention.

Conclusion

LINC02214 is a long non-coding RNA molecule that has been identified using RNA-seq data. Its expression patterns suggest that it may be involved in various cellular processes and its high expression levels in cancer cells and Alzheimer's disease suggest that it may be a promising drug target or biomarker. Further research is needed to fully understand its function and potential as a drug target or biomarker.

Protein Name: Long Intergenic Non-protein Coding RNA 2214

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