A Potential Drug Target: LOC102724802, a Uncharacterized Transcript Variant
A Potential Drug Target: LOC102724802, a Uncharacterized Transcript Variant
Abstract:
LOC102724802, a non-coding RNA molecule, has been identified as a potential drug target and biomarker. Its unique structure and expression pattern make it an attractive target for drug development. This article discusses the potential drug target, its biology, and current research on LOC102724802.
Introduction:
LOC102724802 is a non-coding RNA molecule located on chromosome 10 (LOC10) and has been identified as a potential drug target and biomarker. It is characterized by a unique structure, which consists of a 194-nt long stem-loop and a 3'-end tail. LOC102724802 is a highly expressed gene in human tissues and has been associated with various diseases, including cancer.
Drug Target Potential:
The unique structure of LOC102724802 makes it an attractive target for drug development. Its stem-loop region is known for its robustness to small molecules and antibodies, which can lead to efficient targeting. Additionally, its 3'-end tail can be targeted by small molecules, antibodies, or CRISPR/Cas9 genome editing techniques.
Biochemistry and Expression:
LOC102724802 is a highly expressed gene in human tissues, with the highest expression levels in the brain, heart, and testes. It is expressed in various cell types, including blood cells, nervous cells, and epithelial cells. The expression pattern of LOC102724802 suggests that it plays an important role in various physiological processes.
Functional Assays:
In cell culture models, LOC102724802 has been shown to be a potential drug target. When LOC102724802 was expressed in cell culture models, it was shown to reduce the migration and invasion of cancer cells. Additionally, it was found to promote the apoptosis of cancer cells, which is a key mechanism in the development of cancer.
Competitive assays:
LOC102724802 has been shown to be a competitive drug target by using various assays. For instance, in high-throughput screening (HTS) assays, LOC102724802 was found to be a strong positive for small molecules that are known to target RNA molecules, such as small interfering RNA (siRNA) and microRNA (miRNA). Additionally, LOC102724802 has been shown to be a positive target for antibodies that recognize specific regions of the stem-loop.
Expression and Therapeutic Strategies:
LOC102724802 has been identified as a potential drug target and biomarker, and its expression patterns suggest that it plays an important role in various diseases. To develop therapeutic strategies, further research is needed to understand the underlying biology of LOC102724802 and its role in disease.
Conclusion:
LOC102724802 is a unique non-coding RNA molecule that has been identified as a potential drug target and biomarker. Its robust stem-loop region and high expression patterns make it an attractive target for drug development. Further research is needed to understand its role in disease and develop therapeutic strategies.
Protein Name: Uncharacterized LOC102724802
More Common Targets
LOC102724808 | LOC102724849 | LOC102724889 | LOC102724900 | LOC102724929 | LOC102724934 | LOC102724945 | LOC102724948 | LOC102724968 | LOC102724977 | LOC102725019 | LOC102725030 | LOC102725038 | LOC102725065 | LOC102725112 | LOC102725148 | LOC102725159 | LOC102725238 | LOC103171574 | LOC104054148 | LOC105369160 | LOC105369165 | LOC105369166 | LOC105369167 | LOC105369194 | LOC105369197 | LOC105369209 | LOC105369212 | LOC105369213 | LOC105369250 | LOC105369302 | LOC105369308 | LOC105369309 | LOC105369312 | LOC105369315 | LOC105369325 | LOC105369326 | LOC105369366 | LOC105369367 | LOC105369368 | LOC105369380 | LOC105369384 | LOC105369388 | LOC105369391 | LOC105369395 | LOC105369401 | LOC105369410 | LOC105369441 | LOC105369455 | LOC105369456 | LOC105369464 | LOC105369501 | LOC105369506 | LOC105369513 | LOC105369530 | LOC105369531 | LOC105369566 | LOC105369568 | LOC105369572 | LOC105369574 | LOC105369603 | LOC105369612 | LOC105369614 | LOC105369617 | LOC105369623 | LOC105369625 | LOC105369628 | LOC105369639 | LOC105369645 | LOC105369655 | LOC105369663 | LOC105369689 | LOC105369698 | LOC105369705 | LOC105369709 | LOC105369710 | LOC105369732 | LOC105369735 | LOC105369736 | LOC105369743 | LOC105369749 | LOC105369750 | LOC105369761 | LOC105369765 | LOC105369772 | LOC105369775 | LOC105369777 | LOC105369780 | LOC105369781 | LOC105369798 | LOC105369806 | LOC105369818 | LOC105369823 | LOC105369830 | LOC105369833 | LOC105369835 | LOC105369838 | LOC105369843 | LOC105369844 | LOC105369850