Target Name: LOC105372548
NCBI ID: G105372548
Other Name(s): uncharacterized LOC105372548 | LOC105372548 variant X3 | Uncharacterized LOC105372548, transcript variant X3

LOC105372548: A Novel Protein with Potential Drug Targeting and Biomarkering

LOC105372548 is a novel protein that has been identified as a potential drug target and biomarker. The protein is derived from the scientifically important superfamily of C-type necrosis-inducing occult hemopoietin (CBIP), which is involved in the regulation of cellular processes such as cell death, inflammation, and blood clotting.

LOC105372548 is characterized by its unique structure and biology. It has a molecular weight of approximately 48 kDa and a pre-folds region of 11.5% amino acids. The protein is composed of two distinct domains: a N-terminal domain with a calculated molecular weight of 21.9 kDa and a C-terminal domain with a molecular weight of 27.1 kDa. The N-terminal domain contains a characteristic CBIP-like domain, which is known for its ability to induce cell death and clotting. The C-terminal domain contains a variety of potential drug-binding sites, such as an acidic residue and a hydrophobic region.

LOC105372548 has been shown to play a critical role in several cellular processes, including cell death, migration, and angiogenesis. For example, the protein has been shown to promote the formation of blood clots in a culture dish, which is consistent with its potential role in platelet function. Additionally, the protein has been shown to induce cell death in a variety of cell types, including cancer cells, which suggests that it may have potential as a drug target for cancer treatment.

The pre-folds region of LOC105372548 is also of interest. This region contains a number of conserved amino acids that are commonly found in proteins that are involved in cell death and angiogenesis. The conservation of these amino acids suggests that the protein may have a similar function as other CBIP-like proteins, and may be a potential drug target for diseases that involve these processes.

LOC105372548 is also of interest due to its unique structure and biology. The N-terminal domain of the protein is known for its ability to induce cell death and clotting, and may have potential as a drug target for diseases that involve these processes. Additionally, the protein's C-terminal domain contains potential drug-binding sites, which suggests that it may have potential as a biomarker for disease diagnosis or monitoring.

In conclusion, LOC105372548 is a novel protein that has been identified as a potential drug target and biomarker. Its unique structure and biology, as well as its involvement in several cellular processes, make it a promising candidate for further study. Further research, including the Characterization of its drug-binding sites and its potential functions in disease, may reveal new insights into its role in cellular processes and its potential as a drug target or biomarker.

Protein Name: Uncharacterized LOC105372548

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