A Potential Drug Target: LOC105375974 (Uncharacterized LOC105375974, Transcript Variant X4)
A Potential Drug Target: LOC105375974 (Uncharacterized LOC105375974, Transcript Variant X4)
Abstract:
LOC105375974, also known as Uncharacterized LOC105375974 or Transcript Variant X4, has been identified as a potential drug target and a biomarker for various diseases, including cancer. This protein plays a crucial role in the development and progression of these diseases, and its dysfunction has been associated with the development of various therapeutic approaches. Therefore, the study of LOC105375974 could have significant implications for the development of new treatments for some of the most significant diseases.
Introduction:
LOC105375974 is a non-coding RNA molecule that has been identified in various cellular processes, including cell growth, differentiation, and RNA processing. It is a part of a larger gene family that includes several similar proteins, known as homeobox genes (Hox), which are involved in the regulation of gene expression and cellular processes. LOC105375974 is characterized by a unique single-base polymorphism at its 5' end, which has led to the emergence of several transcript variants.
Expression and localization:
LOC105375974 is expressed in a variety of tissues and cells, including brain, heart, liver, and cancer cells. It is primarily expressed in the brain, where it is involved in the development and maintenance of neural stem cells and the regulation of neuronal excitability. LOC105375974 has also been shown to be involved in the development and progression of various diseases, including cancer. For example, studies have shown that LOC105375974 is overexpressed in various types of cancer, including breast, lung, and ovarian cancer.
Function and biology:
LOC105375974 is a key regulator of the Hox gene family, which is responsible for the development and progression of various diseases. It plays a crucial role in the regulation of cell growth, differentiation, and RNA processing. LOC105375974 is involved in the regulation of stem cell proliferation and the development of neural stem cells, which are important for the development and maintenance of neural tissue.
Additionally, LOC105375974 is involved in the regulation of neuronal excitability, which is critical for the proper functioning of the nervous system. It is involved in the regulation of synaptic plasticity, which is the ability of the brain to change and adapt over time. LOC105375974 is also involved in the regulation of neurotransmitter release, which is critical for the proper functioning of the nervous system.
Drug targeting:
The potential drug targeting of LOC105375974 is based on its involvement in the regulation of cellular processes that are important for the development and progression of various diseases. LOC105375974 is a good candidate for a drug target because it is involved in the regulation of stem cell proliferation, neural stem cell development, and the regulation of neuronal excitability.
In addition, LOC105375974 is also involved in the regulation of synaptic plasticity, which is an important factor in the development and maintenance of neural tissue. Therefore, LOC105375974 could be a potential drug target for diseases that are characterized by the dysfunction of neural tissue, such as
Protein Name: Uncharacterized LOC105375974
More Common Targets
LOC105375976 | LOC105375977 | LOC105375983 | LOC105375984 | LOC105375990 | LOC105375999 | LOC105376001 | LOC105376014 | LOC105376017 | LOC105376035 | LOC105376081 | LOC105376107 | LOC105376110 | LOC105376136 | LOC105376139 | LOC105376156 | LOC105376157 | LOC105376158 | LOC105376161 | LOC105376169 | LOC105376171 | LOC105376177 | LOC105376187 | LOC105376193 | LOC105376196 | LOC105376205 | LOC105376206 | LOC105376208 | LOC105376211 | LOC105376214 | LOC105376219 | LOC105376223 | LOC105376225 | LOC105376234 | LOC105376244 | LOC105376247 | LOC105376250 | LOC105376253 | LOC105376270 | LOC105376287 | LOC105376326 | LOC105376344 | LOC105376356 | LOC105376360 | LOC105376361 | LOC105376372 | LOC105376375 | LOC105376387 | LOC105376391 | LOC105376397 | LOC105376400 | LOC105376407 | LOC105376412 | LOC105376413 | LOC105376422 | LOC105376435 | LOC105376440 | LOC105376442 | LOC105376481 | LOC105376482 | LOC105376483 | LOC105376486 | LOC105376502 | LOC105376504 | LOC105376505 | LOC105376512 | LOC105376523 | LOC105376536 | LOC105376548 | LOC105376558 | LOC105376559 | LOC105376566 | LOC105376576 | LOC105376579 | LOC105376583 | LOC105376595 | LOC105376611 | LOC105376622 | LOC105376626 | LOC105376627 | LOC105376645 | LOC105376659 | LOC105376707 | LOC105376732 | LOC105376740 | LOC105376755 | LOC105376767 | LOC105376781 | LOC105376786 | LOC105376805 | LOC105376809 | LOC105376815 | LOC105376817 | LOC105376818 | LOC105376819 | LOC105376823 | LOC105376845 | LOC105376850 | LOC105376885 | LOC105376898