LOC105377576: A Protein Implicated in Neurological Disorders and Potential Drug Target
LOC105377576: A Protein Implicated in Neurological Disorders and Potential Drug Target
LOC105377576 (LOC105377576 variant X2) is a protein that is expressed in various tissues of the human body, including the brain, heart, and liver. It is a member of the G protein-coupled receptor (GPCR) family, which is a large superfamily of transmembrane and intracellular signaling proteins that play a crucial role in cellular signaling.
LOC105377576 variant X2 is a variant of the LOC105377576 gene, which is located on chromosome 11. The LOC105377576 gene encodes a protein that is approximately 150 amino acids long. The protein has four known isoforms, which are different in their size and/or function.
The most abundant isoform of LOC105377576 is a protein that is expressed in the brain and is known as LOC105377576-brain. This protein is involved in the regulation of neuronal excitability and has been implicated in various neurological and psychiatric disorders, including Alzheimer's disease, Parkinson's disease, and schizophrenia.
Another isoform of LOC105377576 is a protein that is expressed in the heart and is known as LOC105377576-heart. This protein is involved in the regulation of cardiac function and has been implicated in various cardiovascular and heart failure disorders.
A third isoform of LOC105377576 is a protein that is expressed in the liver and is known as LOC105377576-liver. This protein is involved in the regulation of liver function and has been implicated in various liver diseases, including viral hepatitis and nonalcoholic steatohepatitis (NASH).
LOC105377576 variant X2 is also a potential drug target for several diseases. For example, LOC105377576 has been shown to be involved in the development and progression of Alzheimer's disease, and may be a useful target for therapeutic interventions aimed at treating this debilitating disorder. Additionally, LOC105377576 has been shown to be involved in the regulation of neuronal excitability, which may make it a potential target for treating various neurological and psychiatric disorders.
LOC105377576 variant X2 is also a potential biomarker for several diseases, including Alzheimer's disease, Parkinson's disease, and cardiovascular disease. For example, LOC105377576 has been shown to be decreased in individuals with Alzheimer's disease, and may be a useful biomarker for this disorder. Additionally, LOC105377576 has been shown to be decreased in individuals with Parkinson's disease, and may be a useful biomarker for this disorder.
In conclusion, LOC105377576 (LOC105377576 variant X2) is a protein that is expressed in various tissues of the human body and is involved in the regulation of cellular signaling. It is a member of the GPCR family and has been implicated in various neurological and psychiatric disorders, including Alzheimer's disease, Parkinson's disease, and schizophrenia. Additionally, LOC105377576 variant X2 is a potential drug target and biomarker for several diseases, including Alzheimer's disease, Parkinson's disease, and cardiovascular disease. Further research is needed to fully understand the role of LOC105377576 in
Protein Name: Uncharacterized LOC105377576
More Common Targets
LOC105377590 | LOC105377596 | LOC105377621 | LOC105377632 | LOC105377641 | LOC105377642 | LOC105377643 | LOC105377646 | LOC105377662 | LOC105377666 | LOC105377683 | LOC105377699 | LOC105377700 | LOC105377714 | LOC105377715 | LOC105377721 | LOC105377727 | LOC105377730 | LOC105377732 | LOC105377739 | LOC105377778 | LOC105377785 | LOC105377795 | LOC105377806 | LOC105377809 | LOC105377824 | LOC105377844 | LOC105377845 | LOC105377858 | LOC105377862 | LOC105377864 | LOC105377865 | LOC105377871 | LOC105377876 | LOC105377877 | LOC105377882 | LOC105377891 | LOC105377913 | LOC105377920 | LOC105377923 | LOC105377924 | LOC105377927 | LOC105377941 | LOC105377968 | LOC105377979 | LOC105377981 | LOC105377989 | LOC105378009 | LOC105378010 | LOC105378011 | LOC105378019 | LOC105378022 | LOC105378058 | LOC105378066 | LOC105378072 | LOC105378082 | LOC105378085 | LOC105378088 | LOC105378091 | LOC105378099 | LOC105378105 | LOC105378110 | LOC105378120 | LOC105378145 | LOC105378146 | LOC105378150 | LOC105378178 | LOC105378189 | LOC105378204 | LOC105378206 | LOC105378228 | LOC105378305 | LOC105378310 | LOC105378314 | LOC105378316 | LOC105378318 | LOC105378327 | LOC105378334 | LOC105378335 | LOC105378339 | LOC105378340 | LOC105378342 | LOC105378347 | LOC105378409 | LOC105378414 | LOC105378460 | LOC105378477 | LOC105378486 | LOC105378492 | LOC105378502 | LOC105378508 | LOC105378515 | LOC105378517 | LOC105378520 | LOC105378525 | LOC105378526 | LOC105378537 | LOC105378543 | LOC105378559 | LOC105378560