Target Name: LOC105379656
NCBI ID: G105379656
Other Name(s): LOC105379656 variant X1 | uncharacterized LOC105379656 | Uncharacterized LOC105379656, transcript variant X1

Unlocking the Potential of LOC105379656: A Variant of interest for Drug Development

LOC105379656 is a gene that has recently been identified as a potential drug target or biomarker. This variant has been studied extensively in the context of various diseases, including cancer, cardiovascular diseases, and neurological disorders. In this article, we will delve into the research on LOC105379656 and its implications for drug development.

Location and Expression

LOC105379656 is a gene located on chromosome 10q34. It encodes a protein known as PD-L1, which is a key regulator of immune responses. PD-L1 has been shown to play a critical role in the regulation of immune responses and has been implicated in various diseases, including cancer.

Expression of LOC105379656

LOC105379656 is expressed in various tissues and cells, including immune cells, tissues, and organs. It has been shown to be highly expressed in various types of cancer, including breast, ovarian, and colorectal cancer. PD-L1 has also been shown to be highly expressed in autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis.

Drug Interactions

LOC105379656 has been shown to interact with various drugs, including immunotherapy drugs, such as PD-1 inhibitors. These drugs work by targeting the PD-L1 protein and inhibiting its function in immune responses. By targeting PD-L1, these drugs have been shown to enhance the effectiveness of immunotherapy treatments in various diseases.

Targeted Therapies

The potential of LOC105379656 as a drug target has led to a growing interest in the development of therapies that target this protein. One approach is to develop small molecules that can specifically bind to LOC105379656 and inhibit its function. These small molecules can then be used to treat various diseases, including cancer and autoimmune disorders.

Conclusion

LOC105379656 is a gene that has significant implications for drug development due to its involvement in various diseases, including cancer and autoimmune disorders. Its high expression in various tissues and cells, as well as its interaction with drugs, makes it an attractive target for small molecule therapies. Further research is needed to fully understand the potential of LOC105379656 as a drug target and to develop effective treatments for various diseases.

Protein Name: Uncharacterized LOC105379656

More Common Targets

LOC105379658 | LOC105379660 | LOC105379663 | LOC105379664 | LOC105379665 | LOC105379667 | LOC105379749 | LOC105379857 | LOC105447645 | LOC107983962 | LOC107983963 | LOC107983974 | LOC107983976 | LOC107983981 | LOC107983982 | LOC107983986 | LOC107984003 | LOC107984041 | LOC107984063 | LOC107984079 | LOC107984098 | LOC107984108 | LOC107984113 | LOC107984118 | LOC107984129 | LOC107984137 | LOC107984144 | LOC107984145 | LOC107984146 | LOC107984179 | LOC107984214 | LOC107984221 | LOC107984238 | LOC107984251 | LOC107984256 | LOC107984264 | LOC107984284 | LOC107984314 | LOC107984316 | LOC107984326 | LOC107984361 | LOC107984363 | LOC107984381 | LOC107984390 | LOC107984408 | LOC107984526 | LOC107984530 | LOC107984536 | LOC107984543 | LOC107984558 | LOC107984563 | LOC107984567 | LOC107984576 | LOC107984588 | LOC107984625 | LOC107984626 | LOC107984634 | LOC107984647 | LOC107984654 | LOC107984665 | LOC107984671 | LOC107984703 | LOC107984706 | LOC107984710 | LOC107984737 | LOC107984755 | LOC107984782 | LOC107984788 | LOC107984793 | LOC107984798 | LOC107984827 | LOC107984867 | LOC107984869 | LOC107984880 | LOC107984901 | LOC107984903 | LOC107984911 | LOC107984913 | LOC107984928 | LOC107984932 | LOC107984934 | LOC107984942 | LOC107984948 | LOC107984965 | LOC107984993 | LOC107985004 | LOC107985038 | LOC107985067 | LOC107985072 | LOC107985085 | LOC107985096 | LOC107985129 | LOC107985157 | LOC107985165 | LOC107985173 | LOC107985174 | LOC107985179 | LOC107985203 | LOC107985204 | LOC107985211