Understanding the Pseudogene RNA, U6-177P (G106481232)

Target Name: RNU6-177P

NCBI ID: G106481232

Other Name(s): RNA, U6 small nuclear 177, pseudogene

Understanding the Pseudogene RNA, U6-177P

RNA, U6 small nuclear 177 (RNU6-177P), is a molecule that has gained significant interest in recent years due to its unique structure and function. As a pseudogene, RNU6-177P is a non-coding RNA molecule that has been identified in various cellular compartments, including the nucleus, endoplasmic reticulum, and cytoplasm. Its highly conserved sequence and limited expression have led to its potential as a drug target or biomarker.

The RNA molecule, named after its position in the nucleotide sequence, consists of 177 nucleotides and has a unique structure that includes a stem-loop and a 5' end that is heavily influenced by the 3' end. Its conserved secondary structure has been observed in various species, including humans, mouse, and rat, which suggests that it may have a universal function in the cell.

One of the most significant features of RNU6-177P is its ability to interact with various proteins, including transcription factors, DNA-binding proteins, and RNA binding proteins. Its nuclear localization and stability in the nucleus suggest that it plays an important role in gene expression and cell-specific processes.

In addition to its role in gene expression, RNU6-177P has also been shown to play a structural role in the nucleus. Its conserved secondary structure has been observed in various cellular compartments, including the nucleus, endoplasmic reticulum, and cytoplasm. Its nuclear localization and stability in the nucleus suggest that it plays an important role in the regulation of gene expression and cell-specific processes.

Furthermore, the unique structure of RNU6-177P has also led to its potential as a drug target. Its highly conserved sequence and limited expression in various tissues make it an attractive target for small molecules and antibodies that can modulate its function. Additionally, its nuclear localization and stability in the nucleus suggest that it may play a critical role in the regulation of cellular processes that are relevant to various diseases, including cancer.

In conclusion, RNA, U6 small nuclear 177 (RNU6-177P), is a pseudogene that has significant interest in drug targeting and biomarker research due to its unique structure and function. Its conserved secondary structure and limited expression in various cellular compartments make it an attractive target for small molecules and antibodies that can modulate its function. Further research is needed to fully understand its role in gene expression, cell-specific processes, and the regulation of cellular processes that are relevant to various diseases.

Protein Name: RNA, U6 Small Nuclear 177, Pseudogene

More Common Targets