Target Name: ZWINT
NCBI ID: G11130
Other Name(s): Human ZW10 interacting protein-1 | SNAP25 interacting protein of 30 kDa | ZW10 interactor | human ZW10 interacting protein-1 | ZW10 interacting kinetochore protein, transcript variant 1 | ZWINT_HUMAN | ZW10 interacting kinetochore protein, transcript variant 3 | Zwint-1 | zwint-1 | ZWINT variant 3 | ZW10 interactor, kinetochore protein | ZWINT1 | ZW10-interacting protein 1 | ZWINT variant 1 | ZW10 interacting kinetochore protein | ZW10 interactor (isoform a) | MGC117174 | SIP30 | ZWINT variant 2 | HZwint-1 | ZW10 interactor (isoform b) | ZW10 interacting kinetochore protein, transcript variant 2 | KNTC2AP

Study of ZWINT: Potential Drug Target and Biomarker

ZWINT (Human ZW10 interacting protein-1) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a member of the Z-wing family of proteins, which are known for their role in various cellular processes, including cell signaling, migration, and inflammation. ZWINT has been shown to interact with multiple other proteins, including ZWIN2 (Human ZWIN2 interacting protein-2) and ZWIN3 (Human ZWIN3 interacting protein-3).

The study of ZWINT and its associated proteins has important implications for the development of new drugs and biomarkers. By targeting ZWINT with small molecules or other therapeutic agents, researchers may be able to treat a variety of conditions, including neurodegenerative diseases, cardiovascular diseases, and kidney diseases.

One of the challenges in studying ZWINT is its complex cellular localization. ZWINT is expressed in many different tissues throughout the body, and it can be difficult to target a specific protein in a particular tissue. However, recent studies have identified ZWINT as a potential drug target by using techniques such as RNA interference and mass spectrometry. These studies have shown that ZWINT can be targeted by small molecules and have the potential to be a drug for a variety of diseases.

Another promising aspect of ZWINT is its role in cellular signaling. ZWINT has been shown to play a role in a variety of signaling pathways, including the Wnt signaling pathway. This pathway is important for the development and maintenance of tissues and organs, and is involved in many diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases. By targeting ZWINT with small molecules or other therapeutic agents, researchers may be able to activate or inhibit the Wnt signaling pathway and treat a variety of conditions.

In addition to its potential as a drug target, ZWINT has also been shown to be a potential biomarker for a variety of diseases. Its expression has been detected in a variety of tissues and has been associated with the development of many diseases, including neurodegenerative diseases, cardiovascular diseases, and kidney diseases. By targeting ZWINT with small molecules or other therapeutic agents, researchers may be able to use it as a diagnostic or therapeutic tool for a variety of diseases.

Overall, ZWINT is a protein that has significant potential as a drug target and biomarker. Its complex cellular localization and role in cellular signaling make it an attractive target for small molecules and other therapeutic agents. Further research is needed to fully understand the role of ZWINT in disease and to develop effective treatments.

Protein Name: ZW10 Interacting Kinetochore Protein

Functions: Part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity. Required to target ZW10 to the kinetochore at prometaphase

More Common Targets

ZXDA | ZXDB | ZXDC | ZYG11A | ZYG11B | ZYX | ZZEF1 | ZZZ3