LINC01620: A Non-Coding RNA Molecule as A Potential Drug Target

Target Name: LINC01620

NCBI ID: G140834

LINC01620: A Non-Coding RNA Molecule as A Potential Drug Target

LINC01620 is a non-coding RNA molecule that has been identified as a potential drug target (or biomarker) for the treatment of various diseases, including cancer. Its unique structure and biology make it an attractive target for researchers to study and develop new treatments.

The LINC01620 molecule is approximately 200 amino acids long and has a molecular weight of 13.9 kDa. It is made up of a single exon that is predominantly translated to the protein known as NEDD8. NEDD8 is a conserved protein that is involved in a variety of cellular processes, including DNA replication, transcription, and repair.

One of the key features of LINC01620 is its ability to interact with DNA. It has been shown to form a complex with the protein Prm1, which is a key component of the machinery that copies DNA in the cell. This interaction between LINC01620 and Prm1 has has been shown to enhance the transcriptional activity of LINC01620 and increase the levels of NEDD8 in the cell.

Another feature of LINC01620 is its ability to be targeted by small molecules. LINC01620 has a highly conserved free single amino acid residue that is susceptible to small molecules. This has led to the development of a small molecule library that can be used to study the effects of LINC01620 on various cellular processes.

In addition to its potential as a drug target, LINC01620 has also been shown to have potential as a biomarker. Its expression has been shown to be regulated in a variety of tissues and conditions, including cancer. This makes it an attractive target for diagnostic tools and therapies that can be used to monitor the effectiveness of treatments in cancer patients.

The potential of LINC01620 as a drug target is still being explored, but it is clear that it has the potential to be a valuable tool for the treatment of various diseases. Further research is needed to fully understand its biology and develop new treatments.

Protein Name: Long Intergenic Non-protein Coding RNA 1620

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