LINC02691: A Long Intergenic Non-Protein Coding RNA and Potential Drug Target

Target Name: LINC02691

NCBI ID: G145195

Other Name(s): Long intergenic non-protein coding RNA 2691, transcript variant 1 | C14orf144 | long intergenic non-protein coding RNA 2691

LINC02691: A Long Intergenic Non-Protein Coding RNA and Potential Drug Target

LINC02691 is a long intergenic non-protein coding RNA (lncRNA) with a transcript variant number of 1. It is a non-coding RNA molecule that has been identified in various organisms, including humans. LINC02691 is characterized by its unique 21-nt primary structure, which is composed of seven exons and four intron exons. Despite its small size, LINC02691 has been shown to play a significant role in various cellular processes.

One of the key features of LINC02691 is its expression pattern. It is highly expressed in the brain, where it is predominantly expressed in the prefrontal cortex. Additionally, LINC02691 is also expressed in other tissues, including the heart, liver, and kidney. This wide expression pattern suggests that LINC02691 may be involved in a variety of physiological processes, including brain development, progression, and regulation of tissues.

Another feature of LINC02691 is its function. LINC02691 has been shown to play a role in the regulation of cell proliferation and differentiation. It has been shown to promote the growth and survival of various cell types, including cancer cells. Additionally, LINC02691 has also been shown to play a role in the regulation of cell migration and the development of tissues.

Drug Target Potential

The potential drug targeting of LINC02691 is due to its unique expression pattern and its involvement in various cellular processes. The brain-centric expression pattern of LINC02691 makes it a promising candidate for drug targeting. Additionally, the role of LINC02691 in cell proliferation, differentiation, and cell migration suggests that it may be a useful target for therapies aimed at treating various neurological and psychiatric diseases.

One potential mechanism by which LINC02691 may be targeted by drugs is its role in the regulation of cell proliferation. Activation of the RAS/MAPK signaling pathway has been shown to promote the growth and survival of various cancer cells. LINC02691 has been shown to play a role in the regulation of RAS/MAPK signaling, which suggests that it may be a potential target for inhibitors of this pathway.

Another potential mechanism by which LINC02691 may be targeted by drugs is its role in the regulation of cell migration. The F-actinin-1 (FAK) signaling pathway has been shown to play a role in the regulation of cell migration. LINC02691 has been shown to interact with FAK, which suggests that it may be a potential target for agents that inhibit FAK signaling.

Conclusion

LINC02691 is a long intergenic non-protein coding RNA that has been identified in various organisms, including humans. It is characterized by its unique 21-nt primary structure and its high expression in the brain. LINC02691 has been shown to play a role in various cellular processes, including cell proliferation, differentiation, and cell migration. The potential drug targeting of LINC02691 is due to its unique expression pattern and its involvement in various cellular processes. Further research is needed to fully understand the role of LINC02691 in biology and its potential as a drug target.

Protein Name: Long Intergenic Non-protein Coding RNA 2691

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