Somatostatin receptor (nonspecified subtype) Related Diseases

Somatostatin receptor (nonspecified subtype)

Related Diseases

1) Crohn's Disease

2) Arthritis
Arthritis, also known as inflammatory joint disease, is related to rheumatoid arthritis and juvenile rheumatoid arthritis, and has symptoms including arthralgia, back pain and metatarsalgia. An important gene associated with Arthritis is SYK (Spleen Associated Tyrosine Kinase), and among its related pathways/superpathways are Innate Immune System and MIF Mediated Glucocorticoid Regulation. The drugs Entecavir and Chlorhexidine have been mentioned in the context of this disorder. Affiliated tissues include joint, bone and bone marrow, and related phenotypes are Decreased Tat-dependent HIV-LTR-beta-galactosidase protein expression and homeostasis/metabolism

3) Polycystic Liver
Polycystic Liver Disease, also known as autosomal dominant polycystic liver disease, is related to polycystic liver disease 1 with or without kidney cysts and polycystic kidney disease 3 with or without polycystic liver disease, and has symptoms including hepatosplenomegaly An important gene associated with Polycystic Liver Disease is PRKCSH (Protein Kinase C Substrate 80K-H), and among its related pathways/superpathways are WNT Signaling and Bardet-Biedl syndrome. The drugs Miconazole and Sirolimus have been mentioned in the context of this disorder. Affiliated tissues include liver, kidney and pancreas, and related phenotypes are hepatomegaly and abdominal distention

4) Polycystic Kidney, Autosomal Dominant
Autosomal Dominant Polycystic Kidney Disease, also known as polycystic kidney disease, adult type, is related to polycystic kidney disease and polycystic kidney disease 1 with or without polycystic liver disease. An important gene associated with Autosomal Dominant Polycystic Kidney Disease is PKD1 (Polycystin 1, Transient Receptor Potential Channel Interacting), and among its related pathways/superpathways are MicroRNAs in cardiomyocyte hypertrophy and mTOR Signaling. The drugs Candesartan cilexetil and Curcumin have been mentioned in the context of this disorder. Affiliated tissues include kidney, liver and pancreas, and related phenotypes are renal cyst and decreased glomerular filtration rate

5) Cushing Syndrome
Acth-Secreting Pituitary Adenoma, also known as pituitary-dependent cushing's disease, is related to conn's syndrome and pituitary-dependent cushing's disease, and has symptoms including cushingoid facies An important gene associated with Acth-Secreting Pituitary Adenoma is NR3C1 (Nuclear Receptor Subfamily 3 Group C Member 1), and among its related pathways/superpathways are Signal Transduction and Glucocorticoid receptor regulatory network. The drugs Liraglutide and Metformin have been mentioned in the context of this disorder. Affiliated tissues include pituitary, adrenal gland and bone, and related phenotype is liver/biliary system.

6) Heart Failure
Congestive Heart Failure, also known as congestive heart disease, is related to cardiomyopathy, dilated, 1e and orthostatic intolerance, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Congestive Heart Failure is CDKN2B-AS1 (CDKN2B Antisense RNA 1), and among its related pathways/superpathways are Cardiac conduction and "Antiarrhythmic Pathway, Pharmacodynamics". The drugs Salbutamol and Thalidomide have been mentioned in the context of this disorder. Affiliated tissues include Adipose and Lateral Plate Mesoderm, and related phenotypes are muscle and homeostasis/metabolism

7) Depression
Major Depressive Disorder, also known as seasonal affective disorder, is related to anxiety and endogenous depression, and has symptoms including affective symptoms, behavioral symptoms and schizophrenic language. An important gene associated with Major Depressive Disorder is HTR2A (5-Hydroxytryptamine Receptor 2A), and among its related pathways/superpathways are Signal Transduction and Neuroscience. The drugs Fluvoxamine and Valsartan have been mentioned in the context of this disorder. Affiliated tissues include brain, prefrontal cortex and cortex, and related phenotypes are depression and behavior/neurological

8) Inflammatory Bowel Disease
Inflammatory Bowel Disease, also known as inflammatory bowel diseases, is related to inflammatory bowel disease 6 and inflammatory bowel disease 9. An important gene associated with Inflammatory Bowel Disease is IL37 (Interleukin 37). The drugs Copper and Zinc cation have been mentioned in the context of this disorder. Affiliated tissues include colon, small intestine and bone marrow.

9) Idiopathic Pulmonary Fibrosis
Acute Interstitial Pneumonia, also known as acute interstitial pneumonitis, is related to mikulicz disease and pulmonary fibrosis, and has symptoms including dyspnea on exertion and dry cough. An important gene associated with Acute Interstitial Pneumonia is SFTPD (Surfactant Protein D), and among its related pathways/superpathways are Disease and Innate Immune System. The drugs Nintedanib and Protein Kinase Inhibitors have been mentioned in the context of this disorder. Affiliated tissues include lung, bone marrow and bone, and related phenotypes are dyspnea and respiratory failure

10) Pain
Paine Syndrome, also known as pain disorder, is related to paroxysmal extreme pain disorder and indifference to pain, congenital, autosomal recessive. An important gene associated with Paine Syndrome is HFE (Homeostatic Iron Regulator), and among its related pathways/superpathways are Cardiac conduction and Neuropathic Pain-Signaling in Dorsal Horn Neurons. The drugs Pregabalin and Dinoprostone have been mentioned in the context of this disorder. Affiliated tissues include dorsal root ganglion, spinal cord and breast, and related phenotypes are microcephaly and spastic diplegia

11) Cancer, Breast
Breast Cancer, also known as breast carcinoma, is related to ovarian cancer and hereditary breast ovarian cancer syndrome, and has symptoms including pelvic pain, lameness, animal and pain. An important gene associated with Breast Cancer is BRCA2 (BRCA2 DNA Repair Associated), and among its related pathways/superpathways are Gene expression (Transcription) and ERK Signaling. The drugs Prednisolone phosphate and Prednisolone acetate have been mentioned in the context of this disorder. Affiliated tissues include breast, lymph node and prostate, and related phenotypes are breast carcinoma and Decreased viability

12) Cancer, Prostate
Prostate Cancer, also known as prostate carcinoma, is related to breast cancer and prostate disease, and has symptoms including angina pectoris, tremor and equilibration disorder. An important gene associated with Prostate Cancer is CHEK2 (Checkpoint Kinase 2), and among its related pathways/superpathways are Endometrial cancer and Breast cancer pathway. The drugs Sodium citrate and Sildenafil have been mentioned in the context of this disorder. Affiliated tissues include prostate, bone and lymph node, and related phenotypes are prostate cancer and neoplasm

13) Cancer, Lung
Lung Cancer, also known as non-small cell lung carcinoma, is related to lung cancer susceptibility 3 and small cell cancer of the lung, and has symptoms including cough, chest discomfort and weight loss. An important gene associated with Lung Cancer is BRAF (B-Raf Proto-Oncogene, Serine/Threonine Kinase), and among its related pathways/superpathways are Innate Immune System and Apoptotic Pathways in Synovial Fibroblasts. The drugs Pemetrexed and Erlotinib have been mentioned in the context of this disorder. Affiliated tissues include lung, lungs and brain, and related phenotypes are lung adenocarcinoma and alveolar cell carcinoma

14) Neuroendocrine Cancer
Neuroendocrine Carcinoma, also known as carcinoma, neuroendocrine, is related to cervical large cell neuroendocrine carcinoma and lung combined large cell neuroendocrine carcinoma. An important gene associated with Neuroendocrine Carcinoma is SYP (Synaptophysin), and among its related pathways/superpathways are Signal Transduction and Neuroscience. The drugs Picropodophyllin and Pralsetinib have been mentioned in the context of this disorder. Affiliated tissues include lung, pancreas and thyroid, and related phenotypes are no effect and no effect

15) Carcinoid Tumor
Carcinoid Syndrome, also known as carcinoid tumor, is related to carcinoid tumors, intestinal and appendix carcinoid tumor. An important gene associated with Carcinoid Syndrome is SDHD (Succinate Dehydrogenase Complex Subunit D), and among its related pathways/superpathways are Class A/1 (Rhodopsin-like receptors) and Signal Transduction. The drugs Pasireotide and Cyproheptadine have been mentioned in the context of this disorder. Affiliated tissues include heart, lung and small intestine, and related phenotypes are night sweats and small intestine carcinoid

16) Carcinoid Syndrome
Carcinoid Syndrome, also known as carcinoid tumor, is related to carcinoid tumors, intestinal and appendix carcinoid tumor. An important gene associated with Carcinoid Syndrome is SDHD (Succinate Dehydrogenase Complex Subunit D), and among its related pathways/superpathways are Class A/1 (Rhodopsin-like receptors) and Signal Transduction. The drugs Pasireotide and Cyproheptadine have been mentioned in the context of this disorder. Affiliated tissues include heart, lung and small intestine, and related phenotypes are night sweats and small intestine carcinoid

17) Rheumatoid Arthritis
Rheumatoid Arthritis, also known as ra, is related to arthritis and psoriatic arthritis, and has symptoms including back pain, muscle cramp and sciatica. An important gene associated with Rheumatoid Arthritis is PTPN22 (Protein Tyrosine Phosphatase Non-Receptor Type 22), and among its related pathways/superpathways are NF-kappaB Signaling and Genes associated with the development of rheumatoid arthritis. The drugs Entecavir and Alendronic acid have been mentioned in the context of this disorder. Affiliated tissues include Cartilage, joint and bone, and related phenotypes are joint stiffness and fatigue

18) Diabetes
Diabetes Mellitus, also known as diabetes, is related to type 2 diabetes mellitus and gestational diabetes, and has symptoms including angina pectoris, tremor and equilibration disorder. An important gene associated with Diabetes Mellitus is KCNJ11 (Potassium Inwardly Rectifying Channel Subfamily J Member 11), and among its related pathways/superpathways are Regulation of beta-cell development and Cell differentiation - expanded index. The drugs Miconazole and Clotrimazole have been mentioned in the context of this disorder. Affiliated tissues include pancreas, bone marrow and kidney.

19) Sarcoidosis
Sarcoidosis 2, also known as sarcoidosis, susceptibility to, 2, is related to blau syndrome and neurosarcoidosis, and has symptoms including coughing and snoring. An important gene associated with Sarcoidosis 2 is BTNL2 (Butyrophilin Like 2). The drugs Azathioprine and Pirfenidone have been mentioned in the context of this disorder. Affiliated tissues include lung, spleen and lymph node, and related phenotypes are bronchiectasis and pleural effusion

20) Liver Diseases
Liver Disease, also known as liver diseases, is related to non-alcoholic fatty liver disease and fatty liver disease, and has symptoms including abdominal pain, constipation and diarrhea. An important gene associated with Liver Disease is MEG3 (Maternally Expressed 3), and among its related pathways/superpathways are Metabolism and Nuclear receptors meta-pathway. The drugs Perindopril and Amlodipine have been mentioned in the context of this disorder. Affiliated tissues include liver, bone marrow and kidney, and related phenotypes are Reduced mammosphere formation and liver/biliary system

21) Irritable Bowel Syndrome
Irritable Bowel Syndrome, also known as irritable colon, is related to fibromyalgia and lactose intolerance, and has symptoms including abdominal pain, constipation and diarrhea. An important gene associated with Irritable Bowel Syndrome is SLC6A4 (Solute Carrier Family 6 Member 4), and among its related pathways/superpathways are Signal Transduction and GPCR downstream signalling. The drugs Clarithromycin and Simethicone have been mentioned in the context of this disorder. Affiliated tissues include colon, brain and kidney, and related phenotypes are homeostasis/metabolism and nervous system

22) Acromegaly
Acromegaly, also known as gigantism, is related to pituitary adenoma 1, multiple types and pituitary tumors, and has symptoms including endocrine system signs and symptoms An important gene associated with Acromegaly is AIP (Aryl Hydrocarbon Receptor Interacting Protein), and among its related pathways/superpathways are GPCR downstream signalling and Class A/1 (Rhodopsin-like receptors). The drugs Somatostatin and Liraglutide have been mentioned in the context of this disorder. Affiliated tissues include limb, pituitary and bone, and related phenotypes are hyperhidrosis and macroglossia

23) Gastrointestinal Disorders
Gastrointestinal System Disease, also known as gastrointestinal disease, is related to crohn's disease and stomach disease, and has symptoms including peeling tongue, catarrh and blood in stool. An important gene associated with Gastrointestinal System Disease is MIR199A1 (MicroRNA 199a-1), and among its related pathways/superpathways are Cell differentiation - expanded index and miRNAs involved in DNA damage response. The drugs Indomethacin and Racepinephrine have been mentioned in the context of this disorder. Affiliated tissues include gastrointestinal tract, small intestine and liver.

24) Pancreatitis
Acute Pancreatitis, also known as pancreatitis, acute necrotizing, is related to pancreatitis, hereditary and igg4-related disease. An important gene associated with Acute Pancreatitis is CPB1 (Carboxypeptidase B1), and among its related pathways/superpathways are Sudden infant death syndrome (SIDS) susceptibility pathways and CCL18 signaling pathway. The drugs Cefoperazone and Acetylcysteine have been mentioned in the context of this disorder. Affiliated tissues include pancreas, bone marrow and liver, and related phenotypes are no effect and no effect

25) Thymoma, Malignant
Thymic Carcinoma, also known as malignant thymoma, is related to lymphoepithelioma-like thymic carcinoma and thymus adenocarcinoma. An important gene associated with Thymic Carcinoma is KIT (KIT Proto-Oncogene, Receptor Tyrosine Kinase), and among its related pathways/superpathways are Cytoskeletal Signaling and Hippo-Merlin signaling dysregulation. The drugs Paclitaxel and Pembrolizumab have been mentioned in the context of this disorder. Affiliated tissues include thymus, thyroid and bone marrow, and related phenotypes are mediastinal lymphadenopathy and neoplasm of the thymus

26) Diarrhea
Diarrhea, also known as diarrhoea, is related to diarrhea 3, secretory sodium, congenital, with or without other congenital anomalies and microvillus inclusion disease. An important gene associated with Diarrhea is WNT2B (Wnt Family Member 2B), and among its related pathways/superpathways are Embryonic and Induced Pluripotent Stem Cells and Lineage-specific Markers and Digestion and absorption. The drugs Ceftriaxone and Zinc cation have been mentioned in the context of this disorder. Affiliated tissues include colon, small intestine and kidney, and related phenotypes are no effect and no effect

27) Autoimmune Disease
Autoimmune Disease, also known as autoimmune diseases, is related to vitiligo-associated multiple autoimmune disease susceptibility 1 and systemic lupus erythematosus. An important gene associated with Autoimmune Disease is AIS4 (Autoimmune Disease, Susceptibility To, 4), and among its related pathways/superpathways are Innate Immune System and MIF Mediated Glucocorticoid Regulation. The drugs Sofosbuvir and Ledipasvir have been mentioned in the context of this disorder. Affiliated tissues include t cells, bone marrow and skin, and related phenotypes are autoimmune antibody positivity and endocrine/exocrine gland

28) Nutrition Disorders
Nutritional Deficiency Disease, also known as malnutrition, is related to folic acid deficiency anemia and iron deficiency anemia, and has symptoms including abdominal pain, cachexia and constipation. An important gene associated with Nutritional Deficiency Disease is TTR (Transthyretin), and among its related pathways/superpathways are Metabolism of proteins and Glucose / Energy Metabolism. The drugs Heparin, bovine and Tramadol have been mentioned in the context of this disorder. Affiliated tissues include liver, skeletal muscle and breast, and related phenotypes are no effect and no effect

29) Retinopathy, Diabetic
Microvascular Complications of Diabetes 5, also known as diabetic retinopathy, is related to microvascular complications of diabetes 1 and type 1 diabetes mellitus. An important gene associated with Microvascular Complications of Diabetes 5 is PON1 (Paraoxonase 1), and among its related pathways/superpathways are ERK Signaling and Signal Transduction. The drugs Mecobalamin and Hydroxocobalamin have been mentioned in the context of this disorder. Affiliated tissues include Eye, and related phenotypes are homeostasis/metabolism and cardiovascular system

30) Hereditary Hemorrhagic Telangiectasia
Telangiectasia, Hereditary Hemorrhagic, Type 1, also known as orw disease, is related to juvenile polyposis/hereditary hemorrhagic telangiectasia syndrome and pulmonary hypertension, primary, 1, and has symptoms including cyanosis, dyspnea and seizures. An important gene associated with Telangiectasia, Hereditary Hemorrhagic, Type 1 is ENG (Endoglin), and among its related pathways/superpathways are TGF-beta Signaling Pathways and ALK1 signaling events. The drugs Bevacizumab and Antineoplastic Agents, Immunological have been mentioned in the context of this disorder. Affiliated tissues include lung, liver and brain, and related phenotypes are telangiectasia of the skin and hemoptysis

31) Osteosarcoma
Osteogenic Sarcoma, also known as osteosarcoma, is related to bone osteosarcoma and b-cell lymphoma. An important gene associated with Osteogenic Sarcoma is TP53 (Tumor Protein P53), and among its related pathways/superpathways are BRCA1 Pathway and Inhibition of Ribosome Biogenesis by p14(ARF). The drugs Lithium carbonate and Heparin, bovine have been mentioned in the context of this disorder. Affiliated tissues include bone, t cells and lung, and related phenotypes are osteolysis and abnormal femoral metaphysis morphology

32) Hypertension, Portal
Portal Hypertension, also known as hypertension, portal, is related to portal hypertension, noncirrhotic, 2 and hypersplenism, and has symptoms including signs and symptoms, digestive An important gene associated with Portal Hypertension is GIMAP5 (GTPase, IMAP Family Member 5), and among its related pathways/superpathways are Signal Transduction and p70S6K Signaling. The drugs Nitric Oxide and Simvastatin have been mentioned in the context of this disorder. Affiliated tissues include liver, spleen and bone marrow, and related phenotypes are homeostasis/metabolism and growth/size/body region

33) Hyperglycemia
Hyperglycemia is related to type 1 diabetes mellitus and maturity-onset diabetes of the young, type 2, and has symptoms including cachexia, cyanosis and dyspnea. An important gene associated with Hyperglycemia is MALAT1 (Metastasis Associated Lung Adenocarcinoma Transcript 1), and among its related pathways/superpathways are Metabolism and Nervous system development. The drugs Saxagliptin and Aripiprazole have been mentioned in the context of this disorder. Affiliated tissues include endothelial, liver and brain, and related phenotypes are Decreased viability and Decreased viability

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