Disease

Vitiligo


About the Disease
Vitiligo-Associated Multiple Autoimmune Disease Susceptibility 1, also known as vitiligo, is related to alopecia areata and vogt-koyanagi-harada disease, and has symptoms including exanthema and pruritus. An important gene associated with Vitiligo-Associated Multiple Autoimmune Disease Susceptibility 1 is NLRP1 (NLR Family Pyrin Domain Containing 1), and among its related pathways/superpathways are Regulation of expression of SLITs and ROBOs and NF-kappaB Signaling. The drugs Dinoprost tromethamine and Dinoprost have been mentioned in the context of this disorder. Affiliated tissues include skin, thyroid and t cells, and related phenotypes are vitiligo and no effect

Common Targets / Biomarkers
MC1R | CXCR5 | CASP7 | BCL2L12 | DEF8 | CPVL | ERCC1 | IL1RN | IL-15 receptor | FADS2 | TLR4 | Phosphodiesterase IV (PDE4) (nonspecified subtype) | MIR4435-2HG | Melanin | TEF | IL2RA | ACE | Folate Receptor (nonspecified subtype) | PSMB9 | FKBP1A | IL1RAPL1 | NAT2 | TYK2 | LTA | NEK6 | IFNGR1 | HLA-B | COMT | TYR | NR1H3 | IL4R | IRF3 | UBE2E2 | OCLN | LPP | TG | PPP3R2 | HLA-DRB1 | HMGCR | TICAM1 | HLA-G | LINC02265 | RALY | PPP3CC | SMOC2 | FOXD3 | PPP3CA | RERE | CD86 | IL-2 receptor | ABCA1 | FOXP1 | REL | SOD2 | GPX1 | IRF4 | HLA-A | ARID5B | BCHE | IL15 | SYK | CDH1 | TNF | GZMB | FLI1 | SYNGR2 | CBFA2T3 | CES1 | UBASH3A | TSLP | NR3C1 | NPY | TLR2 | BACH2 | TNFAIP3 | HERC2 | CXCR3 | CTLA4 | SPATA48 | TNFRSF11A | VDR | STAT4 | FASN | DDR1 | MYG1 | NOS3 | CD80 | IL2 | EPHA2 | HCG9 | MTHFR | AHR | FASLG | CRHR1 | TXNRD1 | beta-Hexosaminidase Complex | PTPN22 | PON1 | PPP4R3B | IFIH1 | RNASET2 | IFNG | PARP12 | GAA | NOS2 | C1QTNF6 | CXCL10 | FAS | FARP2 | NLRP1 | VEGFA | PPP3CB | LINC02356 | CCR5 | G6PD | PSMB8 | IL21 | PPP3R1 | FYN | GSTP1 | DHFR | PPARGC1B | TAP1 | XPA | IL4 | IL1B | JAK3 | JAK1 | PTPRC | CYP27B1 | HLA-C | IL13 | JAK2 | SLC1A2 | Melanocortin receptor (nonspecified subtype) | FOXP3 | HLA-DQB1 | IL9R | Interleukin 23 complex (IL-23) | IL2RB | ZMIZ1 | PLCB3 | XBP1 | PDCD1 | CAT | PVT1 | XPC | DDC | RAB5C | Protein Phosphatase 2B

Other Diseases

Vitreoretinal Degeneration, Snowflake Type | Vitreoretinopathy, Proliferative | Vogt-Koyanagi-Harada Syndrome | Von Hippel-Lindau Disease | Von Willebrand Disease | Vulvovaginitis | Waardenburg Syndrome | Waardenburg Syndrome Type 1 | Waardenburg Syndrome Type 2 | Waardenburg Syndrome Type 2A | Waardenburg Syndrome Type 2E | Waardenburg Syndrome Type 4 | Waardenburg Syndrome Type 4A | Wagner Disease | WAGR Syndrome | Waldenstrom Macroglobulinemia | Walker-Warburg Syndrome | Warsaw Breakage Syndrome | Weill-Marchesani Syndrome | Werner's Syndrome | Whipple's Disease | Wieacker-Wolff Syndrome | Wiedemann-Steiner Syndrome | Williams Syndrome | Wilson's Disease | Wiskott-Aldrich Syndrome | Withdrawal Syndrome | Wolcott-Rallison Syndrome | Wolff-Parkinson-White Syndrome | Wolfram Syndrome | Wolfram Syndrome 2 | Wolman Disease | Woodhouse-Sakati Syndrome | X-linked Acrogigantism | X-linked Charcot-Marie-Tooth Disease | X-linked Creatine Transporter Deficiency | X-linked Myotubular Myopathy | X-linked Sideroblastic Anemia | Xeroderma Pigmentosum | Xeroderma Pigmentosum Variant Type | Yellow Fever | Zellweger Syndrome | Zimmermann-Laband Syndrome | Zollinger-Ellison Syndrome | Zygomycosis