Hyperuricemia
About the Disease
Hyperuricemia, also known as blood urate raized, is related to hyperuricemia, hprt-related and tubulointerstitial kidney disease, autosomal dominant, 1, and has symptoms including cachexia, cyanosis and dyspnea. An important gene associated with Hyperuricemia is UMOD (Uromodulin), and among its related pathways/superpathways are Metabolism and Transport of inorganic cations/anions and amino acids/oligopeptides. The drugs Levoleucovorin and Mecobalamin have been mentioned in the context of this disorder. Affiliated tissues include kidney, heart and liver, and related phenotypes are renal/urinary system and homeostasis/metabolism
Common Targets / Biomarkers
G432 | Asialoglycoprotein Receptor (ASGPR) (nonspecified subtype) | G6524 | G114548 | G9153 | G1499 | G6655 | G27178 | P12956 | G3659 | G3553 | G5174 | G6580 | G5076 | G3620 | G10786 | G2053 | G6319 | Cholesterol esterase (nonspecified subtype) | G7040 | G5465 | G116085 | G3795 | G7299 | G7099 | G134 | Protein Tyrosine Phosphatase (PTP) (nonspecified subtype) | G9 | G3156 | G1312 | G23411 | P6320 | Adenosine deaminase (nonspecified subtype) | G51393 | G100 | DNA Topoisomerase II (nonspecified subtype) | G2990 | G2646 | G1803 | G231 | G7498 | G6582 | G10050 | G2214 | G43 | G5468 | G6568 | G4860 | G9429 | G8644 | G9971 | G3630 | G2798 | G871 | G55604 | Mitogen-Activated Protein Kinase (nonspecified subtype) | G32 | G4318 | G1559 | G29974 | G9934 | G6523 | G57016 | G56606 | G3558 | G2548 | G4313 | G4233 | G5027 | G5743 | G3458 | G3174 | G5972 | G4363 | G10257 | G348 | P16091 | G197257 | G7124 | G4524 | G5631 | G3586 | G55867
Other Diseases
Hyperuricemic Nephropathy, Familial Juvenile | Hypervalinemia | Hypoalbuminemia | Hypobetalipoproteinemias | Hypocalcemia | Hypodontia | Hypoglycemia | Hypogonadism | Hypohidrotic Ectodermal Dysplasia | Hypohidrotic Ectodermal Dysplasia, X-linked | Hypokalemia | Hypokalemic Periodic Paralysis | Hypolipoproteinemia | Hypomyelination With Atrophy Of Basal Ganglia And Cerebellum | Hypoparathyroidism | Hypophosphatemic Rickets, Autosomal Recessive, 1 | Hypopigmentation | Hypopituitarism | Hypoplastic Left Heart Syndrome | Hypoproteinemia, Hypercatabolic | Hypospadias | Hypotension, Orthostatic | Hypothyroidism | Hypotonia-cystinuria Syndrome | Hypotrichosis | Hypotrichosis Simplex | Hypotrichosis, Congenital, With Juvenile Macular Dystrophy | ICF Syndrome | Ichthyosis | Ichthyosis Bullosa Of Siemens | Ichthyosis Hystrix, Curth-Macklin Type | Ichthyosis, X-linked | Idiopathic Multicentric Castleman Disease | Idiopathic Pulmonary Fibrosis | IgA Deficiency | IgA Nephropathy | Ileitis | IMAGe Syndrome | Imerslund-Grasbeck Syndrome | Immunoproliferative Disorders | Impetigo | Impulse Control Disorder | Inborn Errors Of Metabolism | Incontinentia Pigmenti | Infantile Liver Failure Syndrome 1 | Infantile Nephropathic Cystinosis | Infantile Neuroaxonal Dystrophy | Infantile Refsum Disease | Infantile Spasm | Infectious Diarrhea | Infertility | Infertility, Male | Inflammatory Bowel Disease | Inflammatory Joint Disease | Inflammatory Linear Verrucous Epidermal Nevus | Inflammatory Myofibroblastic Tumor | Inflammatory Myopathy | Influenza | Insulin Resistance | Insulinoma | Intellectual Disability, Autosomal Dominant 5 | Intermittent Claudication | Intermittent Explosive Disorder | Interstitial Lung Diseases | Intestinal Hypomagnesemia 1 | Intestinal Obstruction | Intestinal Pseudo-obstruction | Intestinal Tuberculosis | Intracerebral Hemorrhage | Intracranial Hypertension | Iron Deficiency Anemia | Iron Metabolism Disorders | Iron Overload | Irritable Bowel Syndrome | Ischemia | Isobutyryl-CoA Dehydrogenase Deficiency | Isovaleric Acidemia | Jacobsen Syndrome | Jalili Syndrome | Japanese Encephalitis | Jaundice, Obstructive | Jawad Syndrome | Johanson-Blizzard Syndrome | Joubert Syndrome | Joubert Syndrome 2 | Juvenile Hyaline Fibromatosis | Juvenile Myelomonocytic Leukemia | Juvenile Myoclonic Epilepsy | Juvenile Polyposis | Juvenile Xanthogranuloma | Kabuki Syndrome | Kabuki Syndrome 2 | Kallmann Syndrome | Kaposi Sarcoma | Kaposiform Hemangioendothelioma | Kashin-Beck Disease | Kawasaki Disease | KBG Syndrome | Kearns-Sayre Syndrome | Keloid | Keratitis | Keratitis-ichthyosis-deafness Syndrome | Keratoacanthoma | Keratoconjunctivitis | Keratoconus | Keratocystic Odontogenic Tumor | Keratopathy | Keratosis | Keratosis, Actinic | Keratosis, Seborrheic | Kernicterus | Kidney Stones | Kindler Syndrome | Kleine-Levin Syndrome | Klinefelter Syndrome | Klippel-Feil Syndrome | Knobloch Syndrome | Kohlschutter-Tonz Syndrome | Krabbe Disease | L-2-Hydroxyglutaric Aciduria | Lactose Intolerance | Lafora Disease | Lamellar Ichthyosis | Language Disorders | Large Granular Lymphocytic Leukemia | Larsen Syndrome | Lassa Fever | Lateral Meningocele Syndrome | Lathosterolosis | Lattice Corneal Dystrophy | Lattice Corneal Dystrophy Type 1 | Learning Disability | Leber Congenital Amaurosis | Leber Hereditary Optic Neuropathy | Left Ventricular Noncompaction | Leiomyoma | Leiomyosarcoma | Leishmaniasis, Cutaneous | Leishmaniasis, Visceral | Lennox-Gastaut Syndrome | Lentigo | LEOPARD Syndrome | Leprosy | Leri Pleonosteosis | Leri-Weill Dyschondrosteosis | Lesch-Nyhan Syndrome | Leukemia | Leukemia-lymphoma, Adult T-cell | Leukocyte Adhesion Deficiency | Leukocyte Adhesion Deficiency Type 1 | Leukodystrophies | Leukoencephalopathy, Progressive Multifocal | Leukoplakia | Leukoplakia, Oral | Lewy Body Dementia | Li-Fraumeni Syndrome | Lichen Planus | Lichen Sclerosus | Liddle Syndrome | Liebenberg Syndrome | Light Chain Amyloidosis | Ligneous Conjunctivitis | Limb Girdle Muscular Dystrophy | Lipid Metabolism Disorders | Lipid Storage Diseases | Lipid Storage Myopathy | Lipodystrophy | Lipoma | Lissencephaly 2 | Liver Diseases | Liver Failure | Liver Failure, Acute Infantile | LMNA-related Congenital Muscular Dystrophy | Localized Scleroderma | Loeys-Dietz Syndrome | Loeys-Dietz Syndrome Type 4 | Long QT Syndrome Type 1 | Long QT Syndrome Type 2 | Long QT Syndrome Type 3 | Long-chain 3-hydroxyacyl-coenzyme A Dehydrogenase Deficiency | Low Phospholipid Associated Cholelithiasis | Low Tension Glaucoma | LRBA Deficiency | Lung Diseases | Lupus Erythematosus | Lyme Disease | Lymphangioleiomyomatosis | Lymphangioma | Lymphangiomatosis | Lymphedema | Lymphedema-distichiasis Syndrome | Lymphoma | Lymphoma Lymphoblastic | Lymphoma, AIDS-related | Lymphoma, B-cell | Lymphoma, Follicular | Lymphoma, Mantle Cell | Lymphoma, Primary Cutaneous Anaplastic Large Cell | Lymphomatoid Granulomatosis | Lymphoproliferative Disease, X-linked | Lymphoproliferative Disorders | Lysosomal Acid Lipase Deficiency | Mabry Syndrome | Macrodactyly | Macrophage Activation Syndrome | Macrophagic Myofasciitis | Macular Corneal Dystrophy | Macular Corneal Dystrophy Type 1 | Macular Degeneration | Majeed Syndrome | Major Depression | Malaria | Malaria, Cerebral | Malignant Fibrous Histiocytoma | Malignant Peripheral Nerve Sheath Tumor | Malnutrition | Malonyl-CoA Decarboxylase Deficiency | Mandibuloacral Dysplasia With Type A Lipodystrophy | Mannosidase Deficiency Diseases | Maple Syrup Urine Disease | Marfan Syndrome | Marinesco-Sjogren Syndrome | Marshall-Smith Syndrome | Martsolf Syndrome | Mast Cell Leukemia | Mastitis | Maternally Inherited Diabetes And Deafness | McCune-Albright Syndrome | McKusick Type Metaphyseal Chondrodysplasia | McLeod Syndrome | Measles | Meckel-Gruber Syndrome | Meconium Ileus | Medium-chain Acyl-CoA Dehydrogenase Deficiency | Medulloblastoma | Meesmann Corneal Dystrophy | Megacystis-microcolon-intestinal Hypoperistalsis Syndrome | Megalencephaly | Megaloblastic Anemia | Meier-Gorlin Syndrome | Melanocytic Nevus | Melanoma | Melanoma, Malignant | Melanoma, Uveal | MELAS Syndrome | Meleda Disease | Melnick-Needles Syndrome | Membranous Nephropathy | Meniere's Disease | Meningeal Melanocytoma | Meningioma | Meningioma, Benign | Meningitis | Meningococcal Infections | Meningococcal Meningitis | Menkes Disease | Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis | Mesothelioma, Malignant | Metabolic Diseases | Metabolic Syndrome | Metachondromatosis | Metachromatic Leukodystrophy | Metaphyseal Chondrodysplasia, Schmid Type | Metatropic Dysplasia | Methemoglobinemia | Methemoglobinemia Type IV | Methylmalonic Acidemia | Methylmalonic Aciduria And Homocystinuria, CblC Type | Mevalonate Kinase Deficiency | Microcephalic Osteodysplastic Primordial Dwarfism, Type II | Microcephalic Primordial Dwarfism | Microcephaly | Microcephaly, Seizures, And Developmental Delay | Micropenis | Microphthalmia | Microphthalmia, Syndromic 7 | Microtia | Microvillus Inclusion Disease | Migraine | Milk Allergy | MIRAGE Syndrome | Mitochondrial Cytopathy | Mitochondrial Disease | Mitochondrial DNA Depletion Syndrome | Mitochondrial DNA Depletion Syndrome 13 | Mitochondrial DNA Depletion Syndrome, Encephalomyopathic Form | Mitochondrial DNA Depletion Syndrome, Hepatocerebral Form | Mitochondrial DNA Depletion Syndrome, Myopathic Form | Mitochondrial Encephalomyopathy | Mitochondrial Myopathy | Mixed Connective Tissue Disease | Miyoshi Myopathy | Mohr-Tranebjaerg Syndrome | Molybdenum Cofactor Deficiency | Monilethrix | Mood Disorder | Mosaic Variegated Aneuploidy Syndrome 2 | Motion Sickness | Motor Neuron Diseases | Mountain Sickness | Moyamoya Disease | Muckle-Wells Syndrome | Mucolipidosis | Mucolipidosis Type II | Mucolipidosis Type III | Mucolipidosis Type IV | Mucormycosis | Muir-Torre Syndrome | Multicentric Carpotarsal Osteolysis Syndrome | Multicystic Renal Dysplasia | Multifocal Motor Neuropathy | Multiple Congenital Anomalies-hypotonia-seizures Syndrome 2 | Multiple Epiphyseal Dysplasia | Multiple Hamartoma Syndrome | Multiple Myeloma | Multiple Sclerosis | Multiple Sclerosis, Chronic Progressive | Multiple Sclerosis, Primary Progressive | Multiple Sclerosis, Relapsing-remitting | Multiple Sclerosis, Secondary Progressive | Multiple Sulfatase Deficiency | Multiple System Atrophy | Mumps | Muscle Wasting | Muscular Dystrophy | Myasthenia | Myasthenia Gravis | Mycosis Fungoides | Myelitis | Myelitis, Transverse | Myelodysplasia | Myelofibrosis | Myeloid Leukemia | Myelomeningocele | Myhre Syndrome | Myocardial Infarction | Myocarditis | Myoclonic Atonic Epilepsy | Myoclonic Epilepsy With Ragged Red Fibers | Myoclonus | Myoclonus-dystonia Syndrome | Myofibrillar Myopathy | Myofibromatosis | Myopathy | Myopia | Myosin Storage Myopathy | Myositis | Myositis, Focal | Myotonia | Myotonic Disorders | N-acetylglutamate Synthase Deficiency | Nail-Patella Syndrome | Nance-Horan Syndrome | Nanophthalmos | Narcolepsy | Nasodigitoacoustic Syndrome | NDH Syndrome | Necrobiosis Lipoidica | Necrotizing Autoimmune Myopathy | Nemaline Myopathy | Nemaline Myopathy 10 | Nemaline Myopathy 8 | Neonatal Progeroid Syndrome | Neovascular Glaucoma | Nephritis, Interstitial | Nephroblastoma | Nephrocalcinosis | Nephronophthisis | Nephropathy | Nephrosclerosis | Nephrotic Syndrome | Nephrotic Syndrome Type 1 | Nestor-Guillermo Progeria Syndrome | Netherton Syndrome | Neural Tube Defect | Neuroblastoma | Neurocutaneous Melanocytosis | Neurocutaneous Syndromes | Neurocysticercosis | Neurodegeneration Due To Cerebral Folate Transport Deficiency | Neurodegeneration With Brain Iron Accumulation | Neurodermatitis | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Neurodevelopmental Disorders | Neuroectodermal Tumors, Primitive | Neuroendocrine Cancer | Neurofibroma | Neurofibroma, Plexiform | Neurofibromatosis | Neurofibromatosis Type 1 | Neurofibromatosis Type 2 | Neurofibromatosis-Noonan Syndrome | Neurofibrosarcoma | Neurogenic Bladder | Neuroleptic Malignant Syndrome | Neuroma | Neuromuscular Disorders | Neuromyelitis Optica | Neuromyotonia | Neuronal Ceroid Lipofuscinosis
