Multiple Sclerosis, Chronic Progressive
Multiple Sclerosis, Chronic Progressive
About the Disease
Secondary Progressive Multiple Sclerosis, also known as multiple sclerosis, secondary progressive, is related to relapsing-remitting multiple sclerosis and multiple sclerosis. An important gene associated with Secondary Progressive Multiple Sclerosis is MBP (Myelin Basic Protein), and among its related pathways/superpathways are superpathway of L-citrulline metabolism and Amino acid metabolism. The drugs Dalfampridine and Cladribine have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, brain and spinal cord, and related phenotypes are immune system and hematopoietic system
Common Targets / Biomarkers
G6364
Other Diseases
Multiple Sclerosis, Primary Progressive | Multiple Sclerosis, Relapsing-remitting | Multiple Sclerosis, Secondary Progressive | Multiple Sulfatase Deficiency | Multiple System Atrophy | Mumps | Muscle Wasting | Muscular Dystrophy | Myasthenia | Myasthenia Gravis | Mycosis Fungoides | Myelitis | Myelitis, Transverse | Myelodysplasia | Myelofibrosis | Myeloid Leukemia | Myelomeningocele | Myhre Syndrome | Myocardial Infarction | Myocarditis | Myoclonic Atonic Epilepsy | Myoclonic Epilepsy With Ragged Red Fibers | Myoclonus | Myoclonus-dystonia Syndrome | Myofibrillar Myopathy | Myofibromatosis | Myopathy | Myopia | Myosin Storage Myopathy | Myositis | Myositis, Focal | Myotonia | Myotonic Disorders | N-acetylglutamate Synthase Deficiency | Nail-Patella Syndrome | Nance-Horan Syndrome | Nanophthalmos | Narcolepsy | Nasodigitoacoustic Syndrome | NDH Syndrome | Necrobiosis Lipoidica | Necrotizing Autoimmune Myopathy | Nemaline Myopathy | Nemaline Myopathy 10 | Nemaline Myopathy 8 | Neonatal Progeroid Syndrome | Neovascular Glaucoma | Nephritis, Interstitial | Nephroblastoma | Nephrocalcinosis | Nephronophthisis | Nephropathy | Nephrosclerosis | Nephrotic Syndrome | Nephrotic Syndrome Type 1 | Nestor-Guillermo Progeria Syndrome | Netherton Syndrome | Neural Tube Defect | Neuroblastoma | Neurocutaneous Melanocytosis | Neurocutaneous Syndromes | Neurocysticercosis | Neurodegeneration Due To Cerebral Folate Transport Deficiency | Neurodegeneration With Brain Iron Accumulation | Neurodermatitis | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Neurodevelopmental Disorders | Neuroectodermal Tumors, Primitive | Neuroendocrine Cancer | Neurofibroma | Neurofibroma, Plexiform | Neurofibromatosis | Neurofibromatosis Type 1 | Neurofibromatosis Type 2 | Neurofibromatosis-Noonan Syndrome | Neurofibrosarcoma | Neurogenic Bladder | Neuroleptic Malignant Syndrome | Neuroma | Neuromuscular Disorders | Neuromyelitis Optica | Neuromyotonia | Neuronal Ceroid Lipofuscinosis | Neuropathy | Neutropenia | Nevus | NGLY1 Deficiency | Nicolaides-Baraitser Syndrome | Nicotine Addiction | Nicotine Dependence | Niemann-Pick Disease | Niemann-Pick Disease, Type A | Niemann-Pick Disease, Type B | Niemann-Pick Disease, Type C | Nijmegen Breakage Syndrome | Non-bullous Congenital Ichthyosiform Erythroderma | Non-epidermolytic Palmoplantar Keratoderma | Non-Hodgkin Lymphoma | Non-Langerhans Cell Histiocytosis | Non-proliferative Diabetic Retinopathy | Non-small Cell Lung Cancer | Noonan Syndrome | Noonan Syndrome-like Disorder With Loose Anagen Hair | Norrie Disease | Nutrition Disorders | Obesity | Obesity, Morbid | Obsessive-compulsive Disorder | Ocular Albinism Type 1 | Ocular Hypertension | Ocular Surface Squamous Neoplasia | Oculocutaneous Albinism | Oculocutaneous Albinism Type 1 | Oculocutaneous Albinism Type 2 | Oculocutaneous Albinism Type 4 | Oculodentodigital Dysplasia | Oculopharyngeal Muscular Dystrophy | Odonto-onycho-dermal Dysplasia | Oguchi Disease-2 | Okihiro Syndrome | Oligoasthenoteratozoospermia | Oligoastrocytoma | Oligodendroglioma | Oligospermia | Ollier Disease | Olmsted Syndrome | Omenn Syndrome | Onchocerciasis | Open-angle Glaucoma | Ophthalmia, Sympathetic | Ophthalmoplegia | Opisthorchiasis | Optic Nerve Diseases | Optic Nerve Hypoplasia, Bilateral | Optic Neuropathy | Optic Neuropathy, Anterior Ischemic | Oral Lichen Planus | Ornithine Transcarbamylase Deficiency | Orotic Aciduria | Orthostatic Intolerance | Osmotic Demyelination Syndrome | Osteitis | Osteoarthritis | Osteochondroma | Osteochondrosis | Osteogenesis Imperfecta | Osteogenesis Imperfecta Type II | Osteogenesis Imperfecta Type III | Osteogenesis Imperfecta Type IV | Osteogenesis Imperfecta Type V | Osteogenesis Imperfecta Type VI | Osteoglophonic Dysplasia | Osteomalacia | Osteomyelitis | Osteonecrosis | Osteonecrosis Of The Jaw | Osteopathia Striata With Cranial Sclerosis | Osteopetrosis | Osteoporosis | Osteoporosis, Postmenopausal | Osteoporosis-pseudoglioma Syndrome | Osteosarcoma | Osteosclerosis | Otitis Externa | Otitis Media | Otopalatodigital Syndrome Type 2 | Otosclerosis | Ovarian Hyperstimulation Syndrome | Ovarian Sex Cord-stromal Tumor | Overactive Bladder | Pachyonychia Congenita | Paget's Disease Of The Breast | Pain | Palmoplantar Keratoderma | Palsy, Cerebral | Pancreatitis | Pancreatitis, Chronic | Pancytopenia | Panic Disorder | Panniculitis | Pantothenate Kinase-associated Neurodegeneration | Panuveitis | Papilledema | Papilloma | Papillon-Lefevre Syndrome | Papillorenal Syndrome | Papulopustular Rosacea | Paraganglioma | Paraplegia | Parapsoriasis | Parkinson Disease 6, Autosomal Recessive Early-onset | Parkinson's Disease | Parkinsonism | Paronychia | Paroxysmal Kinesigenic Dyskinesia | Paroxysmal Nocturnal Hemoglobinuria | Partington Syndrome | Parvovirus B19 Infection | PASLI Disease | Patent Ductus Arteriosus | Patent Foramen Ovale | Paternal Uniparental Disomy Of Chromosome 14 | Pathological Gambling | Pearson Syndrome | Peeling Skin Syndrome Type B | Peeling Skin Syndrome, Acral Type | Pelizaeus-Merzbacher Disease | Pelvic Inflammatory Disease | Pemphigoid | Pemphigus | Pemphigus Foliaceus | Pemphigus Vulgaris | Pendred Syndrome | Pericarditis | Periodic Limb Movement Disorder | Periodontitis | Peripheral Neuropathy | Peripheral T-cell Lymphoma | Peritonitis | Perivascular Epithelioid Cell Tumor | Periventricular Leukomalacia | Periventricular Nodular Heterotopia | Pernicious Anemia | Peroxisomal Disorder | Persistent Fetal Circulation | Persistent Hyperplastic Primary Vitreous | Persistent Mullerian Duct Syndrome | Persistent Truncus Arteriosus | Personality Disorders | Peters-plus Syndrome | Peutz-Jeghers Syndrome | Peyronie's Disease | Pfeiffer Syndrome | PHARC Syndrome | Phenylketonuria | Phenylketonuria II | Pheochromocytoma | Phosphoenolpyruvate Carboxykinase Deficiency, Cytosolic | Phosphoglycerate Dehydrogenase Deficiency | Photosensitivity | Pierpont Syndrome | Pierre Robin Syndrome | Pierson Syndrome | Pigment Dispersion Syndrome | Pilomatrix Carcinoma | Pineoblastoma | Pitt-Hopkins Syndrome | Pituitary Disorders | Pituitary Dwarfism | Pituitary Stalk Interruption Syndrome | Placenta Previa | Plasma Cell Dyscrasia | Plasma Cell Leukemia | Plasmacytoma | Platelet Disorders | Platyspondylic Lethal Skeletal Dysplasia, Torrance Type | Pleomorphic Xanthoastrocytoma | Pleural Tuberculosis | Pleurisy | Pneumococcal Meningitis | Pneumoconiosis | Pneumonia, Bacterial | Pneumonia, Mycoplasma | Pneumonia, Viral | Pneumothorax | POEMS Syndrome | Poikiloderma With Neutropenia | Poirier-Bienvenu Neurodevelopmental Syndrome | Polyarteritis Nodosa | Polycystic Kidney, Autosomal Dominant | Polycystic Kidney, Autosomal Recessive | Polycystic Liver | Polycystic Ovary Syndrome | Polycythemia | Polycythemia Vera | Polydactyly | Polymicrogyria | Polymyalgia Rheumatica | Polymyositis | Polyneuropathy | Polyomavirus Nephropathy | Polyradiculopathy | Pompe Disease | Pontocerebellar Hypoplasia | Pontocerebellar Hypoplasia Type 2 | Porencephaly | Poretti-Boltshauser Syndrome | Porokeratosis | Porphyria | Porphyria Cutanea Tarda | Porphyria, Acute Intermittent | Porphyria, Variegate | Portal Vein Thrombosis | Postaxial Polydactyly | Posterior Polar Cataract | Postpartum Depression | Postpoliomyelitis Syndrome | Potocki-Shaffer Syndrome | Pouchitis | Prader-Willi Syndrome | Pre-eclampsia | Preaxial Polydactyly | Precocious Puberty | Prediabetes | Pregnancy, Ectopic | Premature Ejaculation | Premenstrual Syndrome | Presbycusis | Presbyopia | Priapism | Primary Aldosteronism | Primary Biliary Cholangitis | Primary Carnitine Deficiency | Primary Cutaneous Amyloidosis | Primary Erythromelalgia | Primary Familial Brain Calcification | Primary Hyperoxaluria | Primary Hyperoxaluria Type 1 | Primary Hyperoxaluria Type 3 | Primary Lateral Sclerosis | Primary Ovarian Insufficiency | Primary Pigmented Nodular Adrenocortical Disease | Primary Progressive Aphasia | Primary Progressive Nonfluent Aphasia | Primary Sclerosing Cholangitis | Primary Torsion Dystonia | Primrose Syndrome | Proctitis | Progressive Encephalopathy-optic Atrophy Syndrome | Progressive External Ophthalmoplegia | Progressive Familial Intrahepatic Cholestasis | Progressive Familial Intrahepatic Cholestasis Type 1 | Progressive Familial Intrahepatic Cholestasis Type 2 | Progressive Familial Intrahepatic Cholestasis Type 3 | Progressive Myoclonic Epilepsy | Progressive Osseous Heteroplasia | Prolactinoma | Prolidase Deficiency | Prolymphocytic Leukemia | Proopiomelanocortin Deficiency | Prostatitis | Proteasome-associated Autoinflammatory Syndrome 2 | Protein C Deficiency | Protein S Deficiency | Proximal Symphalangism | Prune Belly Syndrome | Prurigo Nodularis | Pseudo-pseudohypoparathyroidism | Pseudoachondroplasia | Pseudoexfoliation Syndrome | Pseudohermaphroditism | Pseudohypoaldosteronism | Pseudohypoparathyroidism Type 1A | Pseudohypoparathyroidism Type 1B | Pseudohypoparathyroidism Type 1C | Pseudohypoparathyroidism Type 2 | Pseudomyxoma Peritonei | Psoriasis | Pterygium | Pulmonary Alveolar Microlithiasis | Pulmonary Alveolar Proteinosis | Pulmonary Capillary Hemangiomatosis | Pulmonary Sclerosing Hemangioma | Pulmonary Stenosis | Pulmonary Tuberculosis | Pulmonary Vein Stenosis | Pulmonary Veno-occlusive Disease | Pulverulent Zonular Cataract | Pupil Disorders | Pure Autonomic Failure | Pure Red Cell Aplasia | Purpura | Purpura, Thrombotic Thrombocytopenic | Pycnodysostosis | Pyelonephritis | Pyloric Stenosis, Infantile Hypertrophic | Pyoderma Gangrenosum | Pyruvate Carboxylase Deficiency Disease | Pyruvate Decarboxylase Deficiency | Pyruvate Dehydrogenase Deficiency | Pyruvate Kinase Deficiency | Raine Syndrome | Rash | Raynaud Phenomenon | Recurrent Respiratory Papillomatosis | Reflex Epilepsy | Relapsing Polychondritis | REM Sleep Behavior Disorder | Renal Dysplasia | Renal Failure | Renal Hypomagnesemia 3 | Renal Hypouricemia | Renal Medullary Carcinoma | Renal Oncocytoma | Renal Tubular Acidosis | Renal Tubular Dysgenesis | Renal-hepatic-pancreatic Dysplasia | Renpenning Syndrome | Restless Legs Syndrome | Restrictive Dermopathy
