Disease

Open-angle Glaucoma


About the Disease
Open-Angle Glaucoma, also known as glaucoma, open-angle, is related to glaucoma 1, open angle, a and exfoliation syndrome. An important gene associated with Open-Angle Glaucoma is MYOC (Myocilin), and among its related pathways/superpathways are Extracellular matrix organization and Burn wound healing. The drugs Tobramycin and Polymyxin B have been mentioned in the context of this disorder. Affiliated tissues include eye, bone marrow and endothelial, and related phenotypes are nervous system and homeostasis/metabolism

Common Targets / Biomarkers
G1588 | G54460 | G102723944 | P13024 | G9968 | G7124 | G9290 | P10264 | G2668 | G10954 | G63970 | G87178 | G4312 | G2329 | G23589 | G105370504 | G1303 | G5373 | G399665 | G102724137 | G11200 | G847 | G3697 | G667 | G6647 | G102467147 | G102724168 | G107986636 | G6507 | G59 | G1909 | G7515 | G84465 | G3824 | G6622 | G654841 | G101927789 | G27178 | G11174 | G6332 | G9686 | Vascular endothelial growth factors (VEGF) (nonspecified subtype) | G3456 | G3791 | G81794 | G5550 | Carbonic Anhydrase (nonspecified subtype) | G627 | G10534 | G114793 | G2200 | G23293 | G8567 | G51559 | G26033 | G1296 | G29119 | G25890 | G3553 | G169792 | G120892 | G7410 | G23224 | G1565 | G100506532 | G11095 | G253559 | G83468 | G145624 | G6472 | G7015 | G4306 | G5582 | G1277 | G10587 | G3620 | G23541 | G22985 | G4940 | G79705 | G1902 | G765 | G9231 | G5792 | G6093 | G57498 | G50863 | G8091 | Alpha-2 Adrenergic receptors (nonspecified subtype) | G207 | G4653 | G54749 | G55577 | G771 | G1269 | G4026 | G100423014 | G65005 | G4519 | G10266 | G57096 | G473 | G29775 | G7082 | G105377927 | G27151 | G1030 | G4321 | G4990 | G123624 | G7099 | G80114 | G100130331 | G145845 | G151449 | G101929244 | G57829 | G134 | P6058 | G100147773 | G105374007 | G10283 | G338773 | G2100 | G57282 | G1289 | alpha-Adrenoceptor (nonspecified subtype) | G6530 | G51422 | G282966 | G1876 | G23268 | G377677 | G8521 | G100287616 | G6601 | G5795 | G766 | G23189 | G160335 | G1768 | G7151 | G54487 | G10979 | G390323 | G19 | G84159 | G101926917 | G51196 | G11218 | G4137 | G1268 | G406958 | G4544 | G100048912 | Uncharacterized LOC102724761 | G23365 | G1265 | G8522 | G10133 | P5867 | G338917 | G137682 | G1859 | G729582 | G6648 | G4016 | G421 | G57448 | G9962 | G105376196 | G105378189 | G2202 | G1029 | G9963 | G581 | P16126 | G8703 | G149047 | K(ATP) Channel (nonspecified subtype) | G135 | G4316 | G220202 | G857 | G4010 | G107984241 | G7143 | G2147 | G730091 | G4052 | G5260 | G55133 | G90 | G105376277 | G153 | G57471 | G5947 | G5742 | G60312 | G5901 | G6649 | G7076 | G7145 | G8527 | G57510 | beta-Adrenoceptor (nonspecified subtype) | G10218 | G4053 | G54499 | G103695433 | G7097 | G55289 | G134430 | G84168 | G11311 | G654 | G4538 | G4973 | G56172 | G2153 | G105372130 | G11078 | G4017 | G107984782 | G5787 | G136371 | G170691 | G5915 | G2099 | G4974 | G9201 | G1292 | G57583 | Platelet-Derived Growth Factor Receptor (nonspecified subtype) | G7042 | G27115 | G57512 | G2194 | Adrenoceptor (nonspecified subtype) | G79841 | G328 | G662 | G2879 | G5731 | G730100 | G259217 | G105378780 | G5080 | G2762 | P11025 | G1690 | G23235 | G51206 | G7010 | G4318 | G80326 | G54828 | G114907 | G3552 | G6523 | G760 | G101930010 | G285780 | G1285 | G2317 | G4846 | G9509 | G85439 | G105374860 | G9475 | G7157 | G54936 | Muscarinic Acetylcholine Receptor (mAChR) (nonspecified subtype) | G8502 | G356 | G1301 | G1607 | G4976 | G2984 | G858 | G284 | G107985463 | G59269 | G4088 | G102723323 | G186 | G60495 | G351 | G64778 | G105370108 | G4763 | G3075 | G23245 | G55770 | G7274 | G28 | G11035 | G4313 | G26153 | G6239 | G358 | G2296 | G745 | G5586 | G1293 | G107986141 | G2581 | G5307 | G107986142 | G1545 | G29110 | G5737 | G10257 | Rho kinase (ROCK) (nonspecified subtype) | G64072 | Potassium Channels (nonspecified subtype) | G441094 | G9641 | G10858 | G221981 | G4909 | G101928638 | G6891 | G348 | G10451 | G5913 | G6311 | G4512 | G10495 | G100533183 | G60412 | G85445 | G101927729 | P10999 | G107986440 | G254100 | G5732 | G64077 | G4524 | G105375077 | G23037 | G80336 | G23762

Other Diseases

Ophthalmia, Sympathetic | Ophthalmoplegia | Opisthorchiasis | Optic Nerve Diseases | Optic Nerve Hypoplasia, Bilateral | Optic Neuropathy | Optic Neuropathy, Anterior Ischemic | Oral Lichen Planus | Ornithine Transcarbamylase Deficiency | Orotic Aciduria | Orthostatic Intolerance | Osmotic Demyelination Syndrome | Osteitis | Osteoarthritis | Osteochondroma | Osteochondrosis | Osteogenesis Imperfecta | Osteogenesis Imperfecta Type II | Osteogenesis Imperfecta Type III | Osteogenesis Imperfecta Type IV | Osteogenesis Imperfecta Type V | Osteogenesis Imperfecta Type VI | Osteoglophonic Dysplasia | Osteomalacia | Osteomyelitis | Osteonecrosis | Osteonecrosis Of The Jaw | Osteopathia Striata With Cranial Sclerosis | Osteopetrosis | Osteoporosis | Osteoporosis, Postmenopausal | Osteoporosis-pseudoglioma Syndrome | Osteosarcoma | Osteosclerosis | Otitis Externa | Otitis Media | Otopalatodigital Syndrome Type 2 | Otosclerosis | Ovarian Hyperstimulation Syndrome | Ovarian Sex Cord-stromal Tumor | Overactive Bladder | Pachyonychia Congenita | Paget's Disease Of The Breast | Pain | Palmoplantar Keratoderma | Palsy, Cerebral | Pancreatitis | Pancreatitis, Chronic | Pancytopenia | Panic Disorder | Panniculitis | Pantothenate Kinase-associated Neurodegeneration | Panuveitis | Papilledema | Papilloma | Papillon-Lefevre Syndrome | Papillorenal Syndrome | Papulopustular Rosacea | Paraganglioma | Paraplegia | Parapsoriasis | Parkinson Disease 6, Autosomal Recessive Early-onset | Parkinson's Disease | Parkinsonism | Paronychia | Paroxysmal Kinesigenic Dyskinesia | Paroxysmal Nocturnal Hemoglobinuria | Partington Syndrome | Parvovirus B19 Infection | PASLI Disease | Patent Ductus Arteriosus | Patent Foramen Ovale | Paternal Uniparental Disomy Of Chromosome 14 | Pathological Gambling | Pearson Syndrome | Peeling Skin Syndrome Type B | Peeling Skin Syndrome, Acral Type | Pelizaeus-Merzbacher Disease | Pelvic Inflammatory Disease | Pemphigoid | Pemphigus | Pemphigus Foliaceus | Pemphigus Vulgaris | Pendred Syndrome | Pericarditis | Periodic Limb Movement Disorder | Periodontitis | Peripheral Neuropathy | Peripheral T-cell Lymphoma | Peritonitis | Perivascular Epithelioid Cell Tumor | Periventricular Leukomalacia | Periventricular Nodular Heterotopia | Pernicious Anemia | Peroxisomal Disorder | Persistent Fetal Circulation | Persistent Hyperplastic Primary Vitreous | Persistent Mullerian Duct Syndrome | Persistent Truncus Arteriosus | Personality Disorders | Peters-plus Syndrome | Peutz-Jeghers Syndrome | Peyronie's Disease | Pfeiffer Syndrome | PHARC Syndrome | Phenylketonuria | Phenylketonuria II | Pheochromocytoma | Phosphoenolpyruvate Carboxykinase Deficiency, Cytosolic | Phosphoglycerate Dehydrogenase Deficiency | Photosensitivity | Pierpont Syndrome | Pierre Robin Syndrome | Pierson Syndrome | Pigment Dispersion Syndrome | Pilomatrix Carcinoma | Pineoblastoma | Pitt-Hopkins Syndrome | Pituitary Disorders | Pituitary Dwarfism | Pituitary Stalk Interruption Syndrome | Placenta Previa | Plasma Cell Dyscrasia | Plasma Cell Leukemia | Plasmacytoma | Platelet Disorders | Platyspondylic Lethal Skeletal Dysplasia, Torrance Type | Pleomorphic Xanthoastrocytoma | Pleural Tuberculosis | Pleurisy | Pneumococcal Meningitis | Pneumoconiosis | Pneumonia, Bacterial | Pneumonia, Mycoplasma | Pneumonia, Viral | Pneumothorax | POEMS Syndrome | Poikiloderma With Neutropenia | Poirier-Bienvenu Neurodevelopmental Syndrome | Polyarteritis Nodosa | Polycystic Kidney, Autosomal Dominant | Polycystic Kidney, Autosomal Recessive | Polycystic Liver | Polycystic Ovary Syndrome | Polycythemia | Polycythemia Vera | Polydactyly | Polymicrogyria | Polymyalgia Rheumatica | Polymyositis | Polyneuropathy | Polyomavirus Nephropathy | Polyradiculopathy | Pompe Disease | Pontocerebellar Hypoplasia | Pontocerebellar Hypoplasia Type 2 | Porencephaly | Poretti-Boltshauser Syndrome | Porokeratosis | Porphyria | Porphyria Cutanea Tarda | Porphyria, Acute Intermittent | Porphyria, Variegate | Portal Vein Thrombosis | Postaxial Polydactyly | Posterior Polar Cataract | Postpartum Depression | Postpoliomyelitis Syndrome | Potocki-Shaffer Syndrome | Pouchitis | Prader-Willi Syndrome | Pre-eclampsia | Preaxial Polydactyly | Precocious Puberty | Prediabetes | Pregnancy, Ectopic | Premature Ejaculation | Premenstrual Syndrome | Presbycusis | Presbyopia | Priapism | Primary Aldosteronism | Primary Biliary Cholangitis | Primary Carnitine Deficiency | Primary Cutaneous Amyloidosis | Primary Erythromelalgia | Primary Familial Brain Calcification | Primary Hyperoxaluria | Primary Hyperoxaluria Type 1 | Primary Hyperoxaluria Type 3 | Primary Lateral Sclerosis | Primary Ovarian Insufficiency | Primary Pigmented Nodular Adrenocortical Disease | Primary Progressive Aphasia | Primary Progressive Nonfluent Aphasia | Primary Sclerosing Cholangitis | Primary Torsion Dystonia | Primrose Syndrome | Proctitis | Progressive Encephalopathy-optic Atrophy Syndrome | Progressive External Ophthalmoplegia | Progressive Familial Intrahepatic Cholestasis | Progressive Familial Intrahepatic Cholestasis Type 1 | Progressive Familial Intrahepatic Cholestasis Type 2 | Progressive Familial Intrahepatic Cholestasis Type 3 | Progressive Myoclonic Epilepsy | Progressive Osseous Heteroplasia | Prolactinoma | Prolidase Deficiency | Prolymphocytic Leukemia | Proopiomelanocortin Deficiency | Prostatitis | Proteasome-associated Autoinflammatory Syndrome 2 | Protein C Deficiency | Protein S Deficiency | Proximal Symphalangism | Prune Belly Syndrome | Prurigo Nodularis | Pseudo-pseudohypoparathyroidism | Pseudoachondroplasia | Pseudoexfoliation Syndrome | Pseudohermaphroditism | Pseudohypoaldosteronism | Pseudohypoparathyroidism Type 1A | Pseudohypoparathyroidism Type 1B | Pseudohypoparathyroidism Type 1C | Pseudohypoparathyroidism Type 2 | Pseudomyxoma Peritonei | Psoriasis | Pterygium | Pulmonary Alveolar Microlithiasis | Pulmonary Alveolar Proteinosis | Pulmonary Capillary Hemangiomatosis | Pulmonary Sclerosing Hemangioma | Pulmonary Stenosis | Pulmonary Tuberculosis | Pulmonary Vein Stenosis | Pulmonary Veno-occlusive Disease | Pulverulent Zonular Cataract | Pupil Disorders | Pure Autonomic Failure | Pure Red Cell Aplasia | Purpura | Purpura, Thrombotic Thrombocytopenic | Pycnodysostosis | Pyelonephritis | Pyloric Stenosis, Infantile Hypertrophic | Pyoderma Gangrenosum | Pyruvate Carboxylase Deficiency Disease | Pyruvate Decarboxylase Deficiency | Pyruvate Dehydrogenase Deficiency | Pyruvate Kinase Deficiency | Raine Syndrome | Rash | Raynaud Phenomenon | Recurrent Respiratory Papillomatosis | Reflex Epilepsy | Relapsing Polychondritis | REM Sleep Behavior Disorder | Renal Dysplasia | Renal Failure | Renal Hypomagnesemia 3 | Renal Hypouricemia | Renal Medullary Carcinoma | Renal Oncocytoma | Renal Tubular Acidosis | Renal Tubular Dysgenesis | Renal-hepatic-pancreatic Dysplasia | Renpenning Syndrome | Restless Legs Syndrome | Restrictive Dermopathy | Reticular Dysgenesis | Retinal Coloboma | Retinal Degeneration | Retinal Detachment | Retinal Diseases | Retinal Dystrophy | Retinal Telangiectasia | Retinal Vasculitis | Retinitis | Retinitis Pigmentosa | Retinitis Pigmentosa 3 | Retinoblastoma | Retinopathy Of Prematurity | Retinopathy, Diabetic | Retinoschisis | Rett Syndrome | Reye Syndrome | Rhabdoid Tumor | Rhabdomyosarcoma | Rhabdomyosarcoma, Alveolar | Rhabdomyosarcoma, Embryonal | Rheumatic Heart Disease | Rheumatoid Arthritis | Rhinitis | Rhizomelic Chondrodysplasia Punctata | Riboflavin Transporter Deficiency Neuronopathy | Richter's Syndrome | Rickets | Rift Valley Fever | Roberts Syndrome | Robinow Syndrome | Rolandic Epilepsy | Rosacea | Rothmund-Thomson Syndrome | Rotor Syndrome | Rubeosis Iridis | Rubinstein-Taybi Syndrome | Saethre-Chotzen Syndrome | Salla Disease | Sandhoff Disease | SAPHO Syndrome | Sarcoidosis | Sarcoidosis, Pulmonary | Sarcoma | Sarcoma, Alveolar Soft Part | Sarcoma, Endometrial Stromal | Sarcoma, Ewing | Sarcomatoid Carcinoma Of The Lung | Sarcosinemia | Saul-Wilson Syndrome | Scabies | Scapuloperoneal Myopathy, X-linked Dominant | Scapuloperoneal Spinal Muscular Atrophy | Schaaf-Yang Syndrome | Schamberg Disease | Schindler Disease | Schistosomiasis | Schistosomiasis Mansoni | Schizencephaly | Schizophrenia | Schizotypal Personality Disorder | Schnitzler Syndrome | Schnyder Crystalline Corneal Dystrophy | Schuurs-Hoeijmakers Syndrome | Schwannoma | Schwannomatosis | Schwartz-Jampel-Aberfeld Syndrome | Scleritis | Sclerocornea | Scleroderma | Scleroderma, Diffuse | Sclerosing Cholangitis | Sclerosteosis | Sclerosteosis 2 | Scoliosis | Seasonal Mood Disorder | Seborrheic Dermatitis | Seizures | Seizures-scoliosis-macrocephaly Syndrome | Seminoma | Sengers Syndrome | Senior-Loken Syndrome | Sensorineural Hearing Loss | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Sensory Neuropathy | Sepiapterin Reductase Deficiency | Sertoli Cell-only Syndrome | Sezary Syndrome | Shock, Cardiogenic | Short-chain Acyl-CoA Dehydrogenase Deficiency | Shprintzen-Goldberg Syndrome | Shwachman-Bodian-Diamond Syndrome | Sialoadenitis | Sick Sinus Syndrome | Sick Sinus Syndrome 1 | Sickle Cell Anemia | Sickle Cell Disease | Silicosis | Silver-Russell Syndrome | Sitosterolemia | Situs Inversus | Sjogren Syndrome | Skin Carcinoma | Skin Fragility-woolly Hair Syndrome | Skin Papilloma | Sleep Apnea | Sleep Apnea, Central | Sleep Apnea, Obstructive | Sleep Disorder | Small Lymphocytic Lymphoma | Smith-Kingsmore Syndrome | Smith-Lemli-Opitz Syndrome | Smith-Magenis Syndrome | Smoldering Myeloma | Snyder-Robinson Syndrome | Sorsby Fundus Dystrophy | Sotos Syndrome | Spastic Paraplegia Type 7 | Spasticity | Specific Granule Deficiency | Speech Disorders | Spina Bifida | Spinal And Bulbar Muscular Atrophy | Spinal Cord Diseases | Spinal Muscular Atrophy | Spinal Muscular Atrophy Type 2 | Spinal Muscular Atrophy Type 3 | Spinal Muscular Atrophy With Progressive Myoclonic Epilepsy | Spinocerebellar Ataxia Type 1