Sarcoma
About the Disease
Malignant Mesenchymoma, also known as malignant mesenchymal tumor, is related to gallbladder sarcoma and leiomyosarcoma. An important gene associated with Malignant Mesenchymoma is SERPINA3 (Serpin Family A Member 3), and among its related pathways/superpathways are Mesenchymal Stem Cells and Lineage-specific Markers and Myogenesis. The drugs Ritonavir and Lopinavir have been mentioned in the context of this disorder. Affiliated tissues include t cells, uterus and bone, and related phenotype is muscle.
Common Targets / Biomarkers
TGFBR2 | EWSR1 | CD19 | TLR7 | Fibroblast Growth Factor Receptor (FGFR) (nonspecified subtype) | TNFRSF10B | ALK | IL2RB | CHEK2 | APC | YES1 | BICRA | MAGEA3 | SRC | NTRK2 | HCK | CTNNB1 | MLH1 | NF2 | KDR | PARP3 | DNA Methyltransferase (DNMT) (nonspecified subtype) | CD248 | FGR | MDM4 | ATM | Protein farnesyltransferase | Vascular endothelial growth factors (VEGF) (nonspecified subtype) | AURKA | CSF3 | TLR8 | OGDH | EGFR | ABL1 | INPP4B | KRAS | FAP | FOXO1 | IGF2R | PTPRD | PDIA2 | gamma-Secretase | FGF3 | Serine/Threonine Kinase (nonspecified subtype) | Pyruvate Dehydrogenase Complex | ASXL1 | FN1 | TMEM132A | CD99 | IL6 | CSK | FZD10 | IDO1 | TERT | SMO | MAPK1 | FAT4 | CTAG1A | ACE2 | HDAC2 | BTK | FGF4 | Heat shock protein 90 (nonspecified subtype) | DNMT3A | HOXB13 | HRAS | KMT2C | ATRX | CCND1 | ELANE | Folate Receptor (nonspecified subtype) | FKBP1A | WDR37 | USP19 | Hedgehog Protein (nonspecified subtype) | NPM1 | JUN | CDK6 | Ephrin Receptor (nonspecified subtype) | CHEK1 | NRAS | PPARA | Protein Kinase B (PKB/Akt) (nonspecified subtype) | LCK | AXL | Phosphatidylinositol 3-kinase (PI3K) (nonspecified subtype) | NF-kappaB (NFkB) | LAG3 | TLR4 | GATA6 | EED | ALDH2 | LOC102724428 | Protein kinase C (nonspecified subtype) | BRD2 | CSF1R | mTOR complex 1 | PDCD1 | CSF3R | TXN | EMSY | KEAP1 | CD3 Complex (T Cell Receptor Complex) | TNFSF11 | FRMD4A | IDH1 | TOP1 | NOTCH1 | CDK4 | SUZ12 | KIT | NOTCH4 | CD274 | ARG1 | DDR2 | GID4 | RNF213 | BCR | XIAP | KAT6A | BRD4 | GADD45A | PIK3CD | FACT complex | DNA Topoisomerase II (nonspecified subtype) | BRAF | FLI1 | CDK9 | HSD11B1 | XPO1 | GATA2 | FOXA1 | CD22 | NTRK3 | RICTOR | PARP1 | LILRB2 | TET2 | CDKN2A | STK11 | PDGFRB | Reverse transcriptase (Telomerase) | PTCH1 | MCL1 | HDAC1 | POT1 | MYC | NTRK1 | FGF10 | GSK3B | DICER1 | ABCG2 | MTOR | mTOR complex 2 | HOPX | IGF1R | EPHB6 | MSMB | HDAC4 | FLT4 | FGF19 | IDH2 | ESR1 | CKS1B | MPL | FRK | KAT6B | RAD51 | KNSTRN | Heat shock protein 70 (nonspecified subtype) | FLT1 | KHDC1 | CCNE1 | RAF1 | SIK2 | BLK | TP53 | PIM1 | DDR1 | RB1 | DGCR2 | BRD3 | ENTPD1 | TH | MDM2 | FASLG | SRSF2 | TNFRSF4 | CTAG1B | NOX3 | Notch receptor (nonspecified subtype) | MAS1 | LYN | Angiotensin receptor (AT) (nonspecified subtype) | Histamine Receptor (HR) (nonspecified subtype) | SYNE1 | SIK1 | LRP2 | DNMT1 | Tubulin | RUNX1 | NF1 | PTGS2 | NT5E | SMARCB1 | LRP1B | PARP2 | MET | PRRC2C | FRS2 | COL2A1 | CTLA4 | TRPA1 | CCR5 | NADPH Oxidase Complex | PIK3CA | ERBB2 | KMT2D | FYN | DAXX | PTPN11 | FAM151A | PDGFRA | ZWINT | FLT3 | RET | ARID1A | MGMT | CD276 | Proteasome Complex | TOP2A | Histone deacetylase (nonspecified subtype) | PPT1 | NADPH Oxidase (nonspecified subtype) | MYLIP | CD226 | ABCB1
Other Diseases
Sarcoma, Alveolar Soft Part | Sarcoma, Endometrial Stromal | Sarcoma, Ewing | Sarcomatoid Carcinoma Of The Lung | Sarcosinemia | Saul-Wilson Syndrome | Scabies | Scapuloperoneal Myopathy, X-linked Dominant | Scapuloperoneal Spinal Muscular Atrophy | Schaaf-Yang Syndrome | Schamberg Disease | Schindler Disease | Schistosomiasis | Schistosomiasis Mansoni | Schizencephaly | Schizophrenia | Schizotypal Personality Disorder | Schnitzler Syndrome | Schnyder Crystalline Corneal Dystrophy | Schuurs-Hoeijmakers Syndrome | Schwannoma | Schwannomatosis | Schwartz-Jampel-Aberfeld Syndrome | Scleritis | Sclerocornea | Scleroderma | Scleroderma, Diffuse | Sclerosing Cholangitis | Sclerosteosis | Sclerosteosis 2 | Scoliosis | Seasonal Mood Disorder | Seborrheic Dermatitis | Seizures | Seizures-scoliosis-macrocephaly Syndrome | Seminoma | Sengers Syndrome | Senior-Loken Syndrome | Sensorineural Hearing Loss | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Sensory Neuropathy | Sepiapterin Reductase Deficiency | Sertoli Cell-only Syndrome | Sezary Syndrome | Shock, Cardiogenic | Short-chain Acyl-CoA Dehydrogenase Deficiency | Shprintzen-Goldberg Syndrome | Shwachman-Bodian-Diamond Syndrome | Sialoadenitis | Sick Sinus Syndrome | Sick Sinus Syndrome 1 | Sickle Cell Anemia | Sickle Cell Disease | Silicosis | Silver-Russell Syndrome | Sitosterolemia | Situs Inversus | Sjogren Syndrome | Skin Carcinoma | Skin Fragility-woolly Hair Syndrome | Skin Papilloma | Sleep Apnea | Sleep Apnea, Central | Sleep Apnea, Obstructive | Sleep Disorder | Small Lymphocytic Lymphoma | Smith-Kingsmore Syndrome | Smith-Lemli-Opitz Syndrome | Smith-Magenis Syndrome | Smoldering Myeloma | Snyder-Robinson Syndrome | Sorsby Fundus Dystrophy | Sotos Syndrome | Spastic Paraplegia Type 7 | Spasticity | Specific Granule Deficiency | Speech Disorders | Spina Bifida | Spinal And Bulbar Muscular Atrophy | Spinal Cord Diseases | Spinal Muscular Atrophy | Spinal Muscular Atrophy Type 2 | Spinal Muscular Atrophy Type 3 | Spinal Muscular Atrophy With Progressive Myoclonic Epilepsy | Spinocerebellar Ataxia Type 1 | Spinocerebellar Ataxia Type 10 | Spinocerebellar Ataxia Type 12 | Spinocerebellar Ataxia Type 13 | Spinocerebellar Ataxia Type 14 | Spinocerebellar Ataxia Type 15 | Spinocerebellar Ataxia Type 16 | Spinocerebellar Ataxia Type 17 | Spinocerebellar Ataxia Type 2 | Spinocerebellar Ataxia Type 20 | Spinocerebellar Ataxia Type 21 | Spinocerebellar Ataxia Type 23 | Spinocerebellar Ataxia Type 27 | Spinocerebellar Ataxia Type 28 | Spinocerebellar Ataxia Type 3 | Spinocerebellar Ataxia Type 31 | Spinocerebellar Ataxia Type 38 | Spinocerebellar Ataxia Type 40 | Spinocerebellar Ataxia Type 42 | Spinocerebellar Ataxia Type 5 | Spinocerebellar Ataxia Type 6 | Spinocerebellar Ataxia Type 7 | Spinocerebellar Ataxia Type 8 | Spitz Nevus | Spitzoid Melanoma | Splenomegaly | Split Hand-foot Malformation | Sponastrime Dysplasia | Spondylo-megaepiphyseal-metaphyseal Dysplasia | Spondylo-ocular Syndrome | Spondyloarthritis | Spondylocarpotarsal Synostosis Syndrome | Spondylocostal Dysostosis | Spondyloepiphyseal Dysplasia Tarda, X-linked | Spondylolisthesis | Spondylometaphyseal Dysplasia | Spondyloperipheral Dysplasia | Spondylosis | Sporadic Hemiplegic Migraine | Sporadic Inclusion Body Myositis | Stargardt Disease | Steel Syndrome | Stevens-Johnson Syndrome | Stickler Syndrome | Stiff-man Syndrome | Still Disease | Stomatitis | Strabismus | Stroke | Stroke, Hemorrhagic | Stroke, Ischemic | Stromal Corneal Dystrophy | Sturge-Weber Syndrome | Stuttering | Stuve-Wiedemann Syndrome | Subacute Sclerosing Panencephalitis | Subcortical Band Heterotopia | Succinic Semialdehyde Dehydrogenase Deficiency | Sulfite Oxidase Deficiency | Superficial Spreading Melanoma | Supravalvular Aortic Stenosis | Sweet Syndrome | Swine Influenza | Syncope | Syndactyly | Synovitis | Synpolydactyly | Syphilis | Systemic Lupus Erythematosus | Systemic Mastocytosis | T-cell Chronic Lymphocytic Leukemia | T-cell Leukemia | T-cell Lymphoma, Subcutaneous Panniculitis-like | T-cell Prolymphocytic Leukemia | Takayasu's Arteritis | Takenouchi-Kosaki Syndrome | Takotsubo Cardiomyopathy | Tangier Disease | Tardive Dyskinesia | TARP Syndrome | Tatton-Brown-Rahman Syndrome | Tay-Sachs Disease | Temporal Lobe Epilepsy | Temtamy Preaxial Brachydactyly Syndrome | Tendinitis | Tendinopathy | Tenosynovial Giant Cell Tumor | Teratozoospermia | Tetanus | Thalassemia | Thalassemia, Beta | Thanatophoric Dysplasia | Thanatophoric Dysplasia Type 1 | Thin Basement Membrane Disease | Thrombasthenia | Thrombocythemia, Essential | Thrombocytopenia | Thromboembolism | Thrombophilia | Thrombophlebitis | Thrombosis | Thrombotic Microangiopathy | Thymoma, Malignant | Thyroid Dysgenesis | Thyroid Dyshormonogenesis | Thyroid Hormone Resistance | Thyroiditis | Thyroiditis, Autoimmune | Thyrotoxic Periodic Paralysis | Tibial Muscular Dystrophy | Tic Disorder | Tietze Syndrome | Tinea | Tinea Versicolor | Tonsillitis | Torticollis | Toxic Epidermal Necrolysis | Toxoplasmosis | Traboulsi Syndrome | Tracheal Disorders | Trachoma | Transcobalamin Deficiency | Transient Bullous Dermolysis Of The Newborn | Transthyretin-related Amyloidosis | Treacher Collins Syndrome | Tremor | Tricho-hepato-enteric Syndrome | Trichomegaly | Trichorhinophalangeal Syndrome | Trichothiodystrophy | Trichotillomania | Trichuriasis | Trigonocephaly | Trimethylaminuria | Triphalangeal Thumb-polysyndactyly Syndrome | Triple A Syndrome | Trismus-pseudocamptodactyly Syndrome | Tuberculosis | Tuberculous Meningitis | Tularemia | Tumoral Calcinosis | Turner's Syndrome | Twin-to-twin Transfusion Syndrome | Tylosis With Esophageal Cancer | Tyrosine Hydroxylase Deficiency | Tyrosinemia | Tyrosinemia Type 1 | Tyrosinemia Type 2 | Ulcerative Colitis | Unverricht-Lundborg Syndrome | Urea Cycle Disorder | Uremia | Uremic Pruritus | Ureteropelvic Junction Obstruction | Urethritis | Urofacial Syndrome | Urolithiasis | Urticaria | Usher Syndrome | Usher Syndrome Type II | Usher Syndrome Type IIC | Usher Syndrome Type III | Uterine Leiomyoma | Uveitis | Uveitis, Anterior | VACTERL Association | VACTERL/VATER Association | Vaginitis | Van Der Knaap Disease | Varicocele | Vascular Calcification | Vascular Cognitive Impairment | Vasculitis | Veno-occlusive Disease | Venous Insufficiency | Ventricular Septal Defect | Vertebrobasilar Insufficiency | Vertigo | Very Long-chain Acyl-CoA Dehydrogenase Deficiency | Vestibular Disease | VEXAS Syndrome | Vici Syndrome | Viral Meningitis | Vitamin A Deficiency | Vitamin B12 Deficiency | Vitamin D Deficiency | Vitamin K Deficiency | Vitelliform Macular Dystrophy | Vitiligo | Vitreoretinal Degeneration, Snowflake Type | Vitreoretinopathy, Proliferative | Vogt-Koyanagi-Harada Syndrome | Von Hippel-Lindau Disease | Von Willebrand Disease | Vulvovaginitis | Waardenburg Syndrome | Waardenburg Syndrome Type 1 | Waardenburg Syndrome Type 2 | Waardenburg Syndrome Type 2A | Waardenburg Syndrome Type 2E | Waardenburg Syndrome Type 4 | Waardenburg Syndrome Type 4A | Wagner Disease | WAGR Syndrome | Waldenstrom Macroglobulinemia | Walker-Warburg Syndrome | Warsaw Breakage Syndrome | Weill-Marchesani Syndrome | Werner's Syndrome | Whipple's Disease | Wieacker-Wolff Syndrome | Wiedemann-Steiner Syndrome | Williams Syndrome | Wilson's Disease | Wiskott-Aldrich Syndrome | Withdrawal Syndrome | Wolcott-Rallison Syndrome | Wolff-Parkinson-White Syndrome | Wolfram Syndrome | Wolfram Syndrome 2 | Wolman Disease | Woodhouse-Sakati Syndrome | X-linked Acrogigantism | X-linked Charcot-Marie-Tooth Disease | X-linked Creatine Transporter Deficiency | X-linked Myotubular Myopathy | X-linked Sideroblastic Anemia | Xeroderma Pigmentosum | Xeroderma Pigmentosum Variant Type | Yellow Fever | Zellweger Syndrome | Zimmermann-Laband Syndrome | Zollinger-Ellison Syndrome | Zygomycosis