Sclerosteosis 2
About the Disease
Sclerosteosis 2, also known as sost2, is related to sclerosteosis 1 and chromosome 2q35 duplication syndrome. An important gene associated with Sclerosteosis 2 is LRP4 (LDL Receptor Related Protein 4), and among its related pathways/superpathways are ncRNAs involved in Wnt signaling in hepatocellular carcinoma and Signaling by WNT. Affiliated tissues include bone, and related phenotypes are macrocephaly and frontal bossing
Common Targets / Biomarkers
G4038
Other Diseases
Scoliosis | Seasonal Mood Disorder | Seborrheic Dermatitis | Seizures | Seizures-scoliosis-macrocephaly Syndrome | Seminoma | Sengers Syndrome | Senior-Loken Syndrome | Sensorineural Hearing Loss | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Sensory Neuropathy | Sepiapterin Reductase Deficiency | Sertoli Cell-only Syndrome | Sezary Syndrome | Shock, Cardiogenic | Short-chain Acyl-CoA Dehydrogenase Deficiency | Shprintzen-Goldberg Syndrome | Shwachman-Bodian-Diamond Syndrome | Sialoadenitis | Sick Sinus Syndrome | Sick Sinus Syndrome 1 | Sickle Cell Anemia | Sickle Cell Disease | Silicosis | Silver-Russell Syndrome | Sitosterolemia | Situs Inversus | Sjogren Syndrome | Skin Carcinoma | Skin Fragility-woolly Hair Syndrome | Skin Papilloma | Sleep Apnea | Sleep Apnea, Central | Sleep Apnea, Obstructive | Sleep Disorder | Small Lymphocytic Lymphoma | Smith-Kingsmore Syndrome | Smith-Lemli-Opitz Syndrome | Smith-Magenis Syndrome | Smoldering Myeloma | Snyder-Robinson Syndrome | Sorsby Fundus Dystrophy | Sotos Syndrome | Spastic Paraplegia Type 7 | Spasticity | Specific Granule Deficiency | Speech Disorders | Spina Bifida | Spinal And Bulbar Muscular Atrophy | Spinal Cord Diseases | Spinal Muscular Atrophy | Spinal Muscular Atrophy Type 2 | Spinal Muscular Atrophy Type 3 | Spinal Muscular Atrophy With Progressive Myoclonic Epilepsy | Spinocerebellar Ataxia Type 1 | Spinocerebellar Ataxia Type 10 | Spinocerebellar Ataxia Type 12 | Spinocerebellar Ataxia Type 13 | Spinocerebellar Ataxia Type 14 | Spinocerebellar Ataxia Type 15 | Spinocerebellar Ataxia Type 16 | Spinocerebellar Ataxia Type 17 | Spinocerebellar Ataxia Type 2 | Spinocerebellar Ataxia Type 20 | Spinocerebellar Ataxia Type 21 | Spinocerebellar Ataxia Type 23 | Spinocerebellar Ataxia Type 27 | Spinocerebellar Ataxia Type 28 | Spinocerebellar Ataxia Type 3 | Spinocerebellar Ataxia Type 31 | Spinocerebellar Ataxia Type 38 | Spinocerebellar Ataxia Type 40 | Spinocerebellar Ataxia Type 42 | Spinocerebellar Ataxia Type 5 | Spinocerebellar Ataxia Type 6 | Spinocerebellar Ataxia Type 7 | Spinocerebellar Ataxia Type 8 | Spitz Nevus | Spitzoid Melanoma | Splenomegaly | Split Hand-foot Malformation | Sponastrime Dysplasia | Spondylo-megaepiphyseal-metaphyseal Dysplasia | Spondylo-ocular Syndrome | Spondyloarthritis | Spondylocarpotarsal Synostosis Syndrome | Spondylocostal Dysostosis | Spondyloepiphyseal Dysplasia Tarda, X-linked | Spondylolisthesis | Spondylometaphyseal Dysplasia | Spondyloperipheral Dysplasia | Spondylosis | Sporadic Hemiplegic Migraine | Sporadic Inclusion Body Myositis | Stargardt Disease | Steel Syndrome | Stevens-Johnson Syndrome | Stickler Syndrome | Stiff-man Syndrome | Still Disease | Stomatitis | Strabismus | Stroke | Stroke, Hemorrhagic | Stroke, Ischemic | Stromal Corneal Dystrophy | Sturge-Weber Syndrome | Stuttering | Stuve-Wiedemann Syndrome | Subacute Sclerosing Panencephalitis | Subcortical Band Heterotopia | Succinic Semialdehyde Dehydrogenase Deficiency | Sulfite Oxidase Deficiency | Superficial Spreading Melanoma | Supravalvular Aortic Stenosis | Sweet Syndrome | Swine Influenza | Syncope | Syndactyly | Synovitis | Synpolydactyly | Syphilis | Systemic Lupus Erythematosus | Systemic Mastocytosis | T-cell Chronic Lymphocytic Leukemia | T-cell Leukemia | T-cell Lymphoma, Subcutaneous Panniculitis-like | T-cell Prolymphocytic Leukemia | Takayasu's Arteritis | Takenouchi-Kosaki Syndrome | Takotsubo Cardiomyopathy | Tangier Disease | Tardive Dyskinesia | TARP Syndrome | Tatton-Brown-Rahman Syndrome | Tay-Sachs Disease | Temporal Lobe Epilepsy | Temtamy Preaxial Brachydactyly Syndrome | Tendinitis | Tendinopathy | Tenosynovial Giant Cell Tumor | Teratozoospermia | Tetanus | Thalassemia | Thalassemia, Beta | Thanatophoric Dysplasia | Thanatophoric Dysplasia Type 1 | Thin Basement Membrane Disease | Thrombasthenia | Thrombocythemia, Essential | Thrombocytopenia | Thromboembolism | Thrombophilia | Thrombophlebitis | Thrombosis | Thrombotic Microangiopathy | Thymoma, Malignant | Thyroid Dysgenesis | Thyroid Dyshormonogenesis | Thyroid Hormone Resistance | Thyroiditis | Thyroiditis, Autoimmune | Thyrotoxic Periodic Paralysis | Tibial Muscular Dystrophy | Tic Disorder | Tietze Syndrome | Tinea | Tinea Versicolor | Tonsillitis | Torticollis | Toxic Epidermal Necrolysis | Toxoplasmosis | Traboulsi Syndrome | Tracheal Disorders | Trachoma | Transcobalamin Deficiency | Transient Bullous Dermolysis Of The Newborn | Transthyretin-related Amyloidosis | Treacher Collins Syndrome | Tremor | Tricho-hepato-enteric Syndrome | Trichomegaly | Trichorhinophalangeal Syndrome | Trichothiodystrophy | Trichotillomania | Trichuriasis | Trigonocephaly | Trimethylaminuria | Triphalangeal Thumb-polysyndactyly Syndrome | Triple A Syndrome | Trismus-pseudocamptodactyly Syndrome | Tuberculosis | Tuberculous Meningitis | Tularemia | Tumoral Calcinosis | Turner's Syndrome | Twin-to-twin Transfusion Syndrome | Tylosis With Esophageal Cancer | Tyrosine Hydroxylase Deficiency | Tyrosinemia | Tyrosinemia Type 1 | Tyrosinemia Type 2 | Ulcerative Colitis | Unverricht-Lundborg Syndrome | Urea Cycle Disorder | Uremia | Uremic Pruritus | Ureteropelvic Junction Obstruction | Urethritis | Urofacial Syndrome | Urolithiasis | Urticaria | Usher Syndrome | Usher Syndrome Type II | Usher Syndrome Type IIC | Usher Syndrome Type III | Uterine Leiomyoma | Uveitis | Uveitis, Anterior | VACTERL Association | VACTERL/VATER Association | Vaginitis | Van Der Knaap Disease | Varicocele | Vascular Calcification | Vascular Cognitive Impairment | Vasculitis | Veno-occlusive Disease | Venous Insufficiency | Ventricular Septal Defect | Vertebrobasilar Insufficiency | Vertigo | Very Long-chain Acyl-CoA Dehydrogenase Deficiency | Vestibular Disease | VEXAS Syndrome | Vici Syndrome | Viral Meningitis | Vitamin A Deficiency | Vitamin B12 Deficiency | Vitamin D Deficiency | Vitamin K Deficiency | Vitelliform Macular Dystrophy | Vitiligo | Vitreoretinal Degeneration, Snowflake Type | Vitreoretinopathy, Proliferative | Vogt-Koyanagi-Harada Syndrome | Von Hippel-Lindau Disease | Von Willebrand Disease | Vulvovaginitis | Waardenburg Syndrome | Waardenburg Syndrome Type 1 | Waardenburg Syndrome Type 2 | Waardenburg Syndrome Type 2A | Waardenburg Syndrome Type 2E | Waardenburg Syndrome Type 4 | Waardenburg Syndrome Type 4A | Wagner Disease | WAGR Syndrome | Waldenstrom Macroglobulinemia | Walker-Warburg Syndrome | Warsaw Breakage Syndrome | Weill-Marchesani Syndrome | Werner's Syndrome | Whipple's Disease | Wieacker-Wolff Syndrome | Wiedemann-Steiner Syndrome | Williams Syndrome | Wilson's Disease | Wiskott-Aldrich Syndrome | Withdrawal Syndrome | Wolcott-Rallison Syndrome | Wolff-Parkinson-White Syndrome | Wolfram Syndrome | Wolfram Syndrome 2 | Wolman Disease | Woodhouse-Sakati Syndrome | X-linked Acrogigantism | X-linked Charcot-Marie-Tooth Disease | X-linked Creatine Transporter Deficiency | X-linked Myotubular Myopathy | X-linked Sideroblastic Anemia | Xeroderma Pigmentosum | Xeroderma Pigmentosum Variant Type | Yellow Fever | Zellweger Syndrome | Zimmermann-Laband Syndrome | Zollinger-Ellison Syndrome | Zygomycosis
