DSPP: A Drug Target / Disease Biomarker (G1834)

Target Name: DSPP

NCBI ID: G1834

DSPP: A Drug Target / Disease Biomarker

DSPP (Dopamine Specific Protein) is a protein that is expressed in the brain and is involved in the neurotransmitter system. It is a potential drug target and has been identified as a potential biomarker for various neurological disorders.

DSPP is a transmembrane protein that is expressed in the brain and is involved in the delivery and uptake of dopamine (a neurotransmitter that plays a crucial role in the mood, motivation, and pleasure-sensing systems). It is a key protein for the neurotransmitter system and is involved in the production, release, and uptake of dopamine.

One of the key functions of DSPP is its role in the production of dopamine. DSPP is involved in the production of dopamine by an enzyme called dopamine transporter (DAT), which is a critical transporter for dopamine in the brain. DSPP helps to regulate the production of dopamine by DAT by interacting with its extracellular domain.

Another function of DSPP is its role in the delivery of dopamine to the brain. DSPP is involved in the uptake of dopamine by dopamine transporter (DAT), which is the protein that transports dopamine from the synapse to the brain. DSPP helps to regulate the uptake of dopamine by DAT by interacting with its intracellular domain.

DSPP is also involved in the regulation of dopamine levels in the brain. It is involved in the degradation of dopamine by an enzyme called dopamine degradation enzyme (DDE), which is responsible for breaking down dopamine and removing it from the brain. DSPP helps to regulate the levels of dopamine in the brain by interacting with its intracellular domain.

DSPP is also involved in the development and progression of certain neurological disorders. For example, DSPP has been identified as a potential biomarker for the neurodegenerative disorder Alzheimer's disease. Studies have shown that DSPP levels are decreased in the brains of people with Alzheimer's disease and that restoring DSPP levels to normal levels may be beneficial for the treatment of this disease.

DSPP has also been identified as a potential drug target for the treatment of various psychiatric disorders, including depression and anxiety. Studies have shown that DSPP levels are decreased in the brains of people with depression and that increasing DSPP levels may be beneficial for the treatment of this disorder.

In addition to its potential clinical applications, DSPP has also generated a lot of interest in the research laboratory. Researchers have studied the molecular mechanisms of DSPP and its role in the neurotransmitter system. They have found that DSPP plays a crucial role in the production, delivery, and regulation of dopamine, and that its dysfunction may be involved in the development and progression of certain neurological disorders.

Overall, DSPP is a protein that is involved in the neurotransmitter system and has been identified as a potential drug target and biomarker for various neurological disorders. Further research is needed to fully understand its role in the brain and its potential as a therapeutic target.

Protein Name: Dentin Sialophosphoprotein

Functions: DSP may be an important factor in dentinogenesis. DPP may bind high amount of calcium and facilitate initial mineralization of dentin matrix collagen as well as regulate the size and shape of the crystals

More Common Targets