ERC1: A Protein Wrangler with Broad Signaling Functions (G23085)

Target Name: ERC1

NCBI ID: G23085

ERC1: A Protein Wrangler with Broad Signaling Functions

ERC1 (MGC12974), also known as G protein-coupled receptor 1, is a protein that plays a crucial role in cellular signaling. It is a member of the G protein-coupled receptor family, which is a large family of transmembrane proteins that play a key role in cellular signaling. ERC1 is expressed in many different tissues and cells in the body, including the brain, heart, and kidneys.

One of the key functions of ERC1 is its role in neurotransmission. ERC1 is involved in the neurotransmitter signals that are used to communicate between neurons and other cells in the nervous system. When a neurotransmitter binds to ERC1, it causes a conformational change that allows the protein to interact with other proteins in the cell. This interaction can lead to the activation or inhibition of various cellular processes, depending on the type of neurotransmitter and the context in which it is used.

ERC1 is also involved in the regulation of pain perception and neuroinflammation. ERC1 has been shown to play a key role in the neurotransmission of pain signals, and it has been implicated in the regulation of neuroinflammation. This is because ERC1 is involved in the production of reactive oxygen species (ROS), which can contribute to the inflammation that follows injury or infection.

In addition to its role in neurotransmission, ERC1 is also involved in the regulation of cell survival. ERC1 has been shown to play a key role in the regulation of cell survival by controlling the levels of intracellular signaling molecules, such as phosphate groups. This is important for maintaining the stability of cells, as changes in the levels of these molecules can affect the survival and proliferation of cells.

ERC1 is also involved in the regulation of inflammation and immune responses. ERC1 has been shown to play a key role in the regulation of inflammation and immune responses by controlling the production of pro-inflammatory cytokines. This is important for maintaining the balance between inflammation and immune responses, and for promoting the immune system's response to infection.

Given its involvement in so many different cellular processes, ERC1 is a promising drug target. Researchers are currently working to develop drugs that can selectively target ERC1 and modulate its activity. These drugs may have a wide range of potential applications, including the treatment of a variety of neurological and psychiatric disorders.

In conclusion, ERC1 (MGC12974) is a protein that plays a crucial role in cellular signaling and has a wide range of functions in the body. Its role in neurotransmission, pain perception, inflammation, and immune responses makes it an attractive drug target for the development of new therapeutic compounds. As research continues to advance, it is likely that new insights into the biology of ERC1 will emerge, further expanding its potential as a drug target.

Protein Name: ELKS/RAB6-interacting/CAST Family Member 1

Functions: Regulatory subunit of the IKK complex. Probably recruits IkappaBalpha/NFKBIA to the complex. May be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. May be involved in vesicle trafficking at the CAZ. May be involved in Rab-6 regulated endosomes to Golgi transport

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