Target Name: CXCR1
NCBI ID: G3577
Other Name(s): C-X-C chemokine receptor type 1 | CKR-1 | chemokine (C-X-C motif) receptor 1 | CMKAR1 | CD128 | IL8RBA | C-C | interleukin-8 receptor type A | high affinity interleukin-8 receptor A | C-X-C motif chemokine receptor 1 | IL-8 receptor type 1 | IL8R1 | CD181 | IL8RA | CXCR1_HUMAN | CDw128a | High affinity interleukin-8 receptor A | interleukin 8 receptor, alpha | C-C-CKR-1 | Interleukin 8 receptor alpha | interleukin-8 receptor type 1 | IL-8R A | CXC-R1 | CXCR-1

CXCR1: Key Receptor for Immune, Cell-Mediated, Inflammation and Stem Cell Biology

CXCR1, also known as chemokine receptor type 1, is a protein that is expressed in various cell types in the body. It is a member of the chemokine receptor family, which is a group of transmembrane proteins that play a crucial role in the regulation of cellular behavior, including the process of cell-mediated signaling.

One of the key functions of CXCR1 is its role in the regulation of immune responses. It is expressed in T cells, which are a critical part of the immune system and play a crucial role in protecting the body against infection and disease. CXCR1 is involved in the process of T cell activation and proliferation, as well as the regulation of T cell death.

CXCR1 is also involved in the regulation of cell-mediated signaling, which is the process by which cells communicate with one another and with their environment. It is part of a signaling pathway that is critical for the regulation of cell behavior, including the process of cell migration and the formation of tissues.

CXCR1 is also involved in the regulation of inflammation. It is a key receptor for pro-inflammatory cytokines, which are molecules that play a crucial role in the regulation of inflammation. CXCR1 is involved in the regulation of the production and response to these cytokines, as well as the regulation of inflammation-related signaling pathways.

CXCR1 is also involved in the regulation of pain perception. It is a key receptor for pain-related cytokines, which are molecules that play a crucial role in the regulation of pain. CXCR1 is involved in the regulation of the production and response to these cytokines , as well as the regulation of pain-related signaling pathways.

CXCR1 is also involved in the regulation of stem cell biology. It is a key receptor for stem cell growth factors, which are molecules that play a crucial role in the regulation of stem cell biology. CXCR1 is involved in the regulation of the production and response to these growth factors, as well as the regulation of stem cell-related signaling pathways.

CXCR1 is also involved in the regulation of tissue repair. It is a key receptor for tissue repair factors, which are molecules that play a crucial role in the regulation of tissue repair. CXCR1 is involved in the regulation of the production and response to these factors , as well as the regulation of tissue repair-related signaling pathways.

In conclusion, CXCR1 is a protein that is involved in a wide range of cellular processes in the body. It is a key receptor for various cytokines and growth factors, as well as for pain-related and tissue repair factors. Its role in these processes makes CXCR1 an attractive drug target and a potential biomarker for a variety of diseases. Further research is needed to fully understand the functions of CXCR1 and its potential as a drug.

Protein Name: C-X-C Motif Chemokine Receptor 1

Functions: Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor (PubMed:1840701). Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system (PubMed:8662698)

More Common Targets

CXCR2 | CXCR2P1 | CXCR3 | CXCR4 | CXCR5 | CXCR6 | CXorf30 | CXorf38 | CXorf49 | CXorf49B | CXorf51A | CXorf51B | CXorf58 | CXorf65 | CXorf66 | CXXC1 | CXXC1P1 | CXXC4 | CXXC4-AS1 | CXXC5 | CYB561 | CYB561A3 | CYB561D1 | CYB561D2 | CYB5A | CYB5B | CYB5D1 | CYB5D2 | CYB5R1 | CYB5R2 | CYB5R3 | CYB5R4 | CYB5RL | CYBA | CYBB | CYBC1 | CYBRD1 | CYC1 | Cyclin | Cyclin A | Cyclin B | Cyclin D | Cyclin D2-CDK4 complex | Cyclin-dependent kinase | Cyclin-dependent kinase inhibitor | Cyclooxygenase (COX) | Cyclophilins | CYCS | CYCSP25 | CYCSP34 | CYCSP38 | CYCSP51 | CYCSP52 | CYCSP53 | CYCSP55 | CYFIP1 | CYFIP2 | CYGB | CYLC1 | CYLC2 | CYLD | CYLD-AS1 | CYMP | CYP11A1 | CYP11B1 | CYP11B2 | CYP17A1 | CYP19A1 | CYP1A1 | CYP1A2 | CYP1B1 | CYP1B1-AS1 | CYP20A1 | CYP21A1P | CYP21A2 | CYP24A1 | CYP26A1 | CYP26B1 | CYP26C1 | CYP27A1 | CYP27B1 | CYP27C1 | CYP2A13 | CYP2A6 | CYP2A7 | CYP2A7P1 | CYP2B6 | CYP2B7P | CYP2C18 | CYP2C19 | CYP2C61P | CYP2C8 | CYP2C9 | CYP2D6 | CYP2D7 | CYP2D8P | CYP2E1 | CYP2F1 | CYP2F2P | CYP2G1P