Target Name: C2CD4B
NCBI ID: G388125
Other Name(s): C2 calcium-dependent domain-containing protein 4B | NLF2 | C2C4B_HUMAN | nuclear localized factor 2 | Nuclear-localized factor 2 | Protein FAM148B | Family with sequence similarity 148, member B | family with sequence similarity 148, member B | C2 calcium dependent domain containing 4B | FAM148B | Nuclear localized factor 2

C2CD4B: A Potential Drug Target and Biomarker for Chronic Pain

Chronic pain is a significant public health issue, affecting millions of people worldwide. The persistent nature of pain can have a significant impact on an individual's quality of life and overall well-being. In addition, chronic pain can also lead to other comorbidities, such as depression, anxiety, and cardiovascular disease. Therefore, the development of new treatments and biomarkers for chronic pain is of great interest.

C2CD4B: A protein with Potential as a Drug Target

The C2CD4B protein is a member of the superfamily of calcium-dependent chloride channels, which are involved in a wide range of physiological processes, including muscle contractions, nerve function, and inflammation. The C2CD4B protein was identified as a potential drug target for chronic pain due to its unique structure and its involvement in pain signaling.

C2CD4B is expressed in various tissues, including brain, spinal cord, muscle, and peripheral nerves. It is involved in the regulation of pain signaling, which is a critical function of the nervous system. The C2CD4B protein is known to play a role in the regulation of neurotransmitter release, which is critical for the transmission of pain signals from the pain receptor to the brain.

In addition, C2CD4B is also involved in the regulation of pain modulation, which is the process by which the brain and spinal cord adapt to chronic pain. The C2CD4B protein is known to play a role in the regulation of pain modulation by modulating the activity of GABA, a neurotransmitter that plays a critical role in the regulation of pain signaling.

C2CD4B as a Biomarker for Chronic Pain

The C2CD4B protein is also potential biomarker for chronic pain due to its expression and involvement in pain signaling. The C2CD4B protein is known to be expressed in various tissues and is involved in the regulation of pain signaling, which is a critical function of the nervous system. Therefore, the C2CD4B protein can be used as a biomarker for chronic pain.

C2CD4B is involved in the regulation of pain signaling by modulating the activity of GABA, a neurotransmitter that plays a critical role in the regulation of pain signaling. Therefore, changes in the expression and activity of C2CD4B can be an indication of chronic pain. For example, reduced expression and activity of C2CD4B can be an indication of chronic pain, while increased expression and activity can be an indication of neuroinflammation.

In addition, the C2CD4B protein is involved in the regulation of pain modulation, which is the process by which the brain and spinal cord adapt to chronic pain. Therefore, changes in the expression and activity of C2CD4B can also be an indication of chronic pain. For example, increased expression and activity of C2CD4B can be an indication of chronic pain, while decreased expression and activity can be an indication of neuroplasticity.

Conclusion

In conclusion, C2CD4B is a protein with potential as a drug target for chronic pain due to its unique structure and its involvement in pain signaling. The C2CD4B protein is expressed in various tissues and is involved in the regulation of pain signaling, which is a critical function of the nervous system. Therefore, changes in the expression and activity of C2CD4B can be used as biomarkers for chronic pain. Further research is needed to determine the role of C2CD4B as a drug target for chronic pain and to develop new treatments for chronic pain.

Protein Name: C2 Calcium Dependent Domain Containing 4B

Functions: May be involved in inflammatory process. May regulate cell architecture and adhesion

More Common Targets

C2CD4C | C2CD4D | C2CD4D-AS1 | C2CD5 | C2CD6 | C2orf15 | C2orf16 | C2orf27A | C2orf42 | C2orf48 | C2orf49 | C2orf50 | C2orf66 | C2orf68 | C2orf69 | C2orf72 | C2orf73 | C2orf74 | C2orf74-DT | C2orf76 | C2orf78 | C2orf80 | C2orf81 | C2orf83 | C2orf88 | C2orf92 | C3 | C3AR1 | C3orf14 | C3orf18 | C3orf20 | C3orf22 | C3orf33 | C3orf36 | C3orf38 | C3orf49 | C3orf52 | C3orf62 | C3orf70 | C3orf80 | C3orf84 | C3orf85 | C3orf86P | C3P1 | C4A | C4B | C4BPA | C4BPAP2 | C4BPB | C4B_2 | C4orf17 | C4orf19 | C4orf3 | C4orf33 | C4orf36 | C4orf45 | C4orf46 | C4orf46P3 | C4orf47 | C4orf48 | C4orf50 | C4orf51 | C4orf54 | C5 | C5-OT1 | C5AR1 | C5AR2 | C5orf15 | C5orf22 | C5orf24 | C5orf34 | C5orf46 | C5orf47 | C5orf52 | C5orf58 | C5orf60 | C5orf63 | C5orf64 | C5orf64-AS1 | C5orf67 | C6 | C6orf118 | C6orf120 | C6orf132 | C6orf136 | C6orf141 | C6orf15 | C6orf163 | C6orf226 | C6orf47 | C6orf52 | C6orf58 | C6orf62 | C6orf89 | C7 | C7orf13 | C7orf25 | C7orf31 | C7orf33 | C7orf50