miRNA 181a-1: A Potential Drug Target for Cancer (G406995)
miRNA 181a-1: A Potential Drug Target for Cancer
MicroRNA (miRNA) 181a-1 is a non-coding RNA molecule that plays a critical role in regulating various cellular processes. It is a part of a family of miRNAs known as miR181 family, which are known to play a crucial role in various cellular processes. processes such as cell growth, differentiation, and apoptosis.
MiRNA 181a-1 is characterized by a unique structure, which consists of a hairpin-like domain and a 3' non-coding region. The hairpin-like domain is responsible for the formation of a stable complex with the target protein, while the 3 ' non-coding region is involved in the regulation of the target protein's stability and translation efficiency.
MiRNA 181a-1 has been shown to play a role in various cellular processes, including cell growth, apoptosis, and transcriptional regulation. It has been shown to regulate the expression of various genes, including Lycorin, a gene involved in apoptosis death-related genes.
In addition, miRNA 181a-1 also interacts with many proteins, including some related to apoptosis. These proteins may play a key role in apoptosis, and therefore, miRNA 181a-1 is considered a potential drug target (or biomarker).
Currently, miRNA 181a-1 has been shown to play an important role in a variety of cancers, including lung cancer, breast cancer, and neuroblastoma. Studies have shown that the expression level of miRNA 181a-1 is negatively correlated with the survival rate of cancer patients.
In addition, miRNA 181a-1 also interacts with other members of the miR181 family, including miR181b, miR181c, and miR181d. These miRNAs play an important role in regulating apoptosis and interact with miRNA 181a-1 to jointly regulate apoptosis.
The effects of miRNA 181a-1 are also subject to multiple modulations, including post-transcriptional modification and co-expression. miRNA 181a-1 can be knocked down through RNA interference (RNAi) technology, which will lead to a reduction in its expression level. Furthermore, co-expression network analysis revealed that miRNA 181a-1 interacts with multiple proteins, which may be key factors in the expression and function of miRNA 181a-1.
miRNA 181a-1 is also related to the degradation of miR181a-1. miRNA 181a-1 can be degraded through phosphorylation modification, which is an important degradation mechanism that helps maintain the stability of miRNA 181a-1.
miRNA 181a-1 is an important molecule that plays a key role in apoptosis and tumorigenesis. Because miRNA 181a-1 is down-regulated in a variety of cancers, it is considered a potential drug target (or biomarker). In addition, miRNA 181a-1 interacts with other members of the miR181 family to jointly regulate apoptosis, which provides an important theoretical basis for studying the role of miRNA 181a-1.
Protein Name: MicroRNA 181a-1
More Common Targets
MIR181A1HG | MIR181A2 | MIR181A2HG | MIR181B1 | MIR181B2 | MIR181C | MIR181D | MIR182 | MIR1825 | MIR1827 | MIR183 | MIR184 | MIR185 | MIR186 | MIR187 | MIR188 | MIR18A | MIR18B | MIR1908 | MIR1909 | MIR190A | MIR190B | MIR191 | MIR1910 | MIR1911 | MIR1912 | MIR1913 | MIR1914 | MIR1915 | MIR1915HG | MIR192 | MIR193A | MIR193B | MIR193BHG | MIR194-1 | MIR194-2 | MIR194-2HG | MIR195 | MIR196A1 | MIR196A2 | MIR196B | MIR197 | MIR1972-1 | MIR1972-2 | MIR1973 | MIR1976 | MIR198 | MIR199A1 | MIR199A2 | MIR199B | MIR19A | MIR19B1 | MIR19B2 | MIR200A | MIR200B | MIR200C | MIR200CHG | MIR202 | MIR202HG | MIR203A | MIR203B | MIR204 | MIR205 | MIR2052 | MIR2052HG | MIR2053 | MIR2054 | MIR205HG | MIR206 | MIR208A | MIR208B | MIR20A | MIR20B | MIR21 | MIR210 | MIR210HG | MIR211 | MIR2110 | MIR2113 | MIR2114 | MIR2115 | MIR2116 | MIR2117 | MIR212 | MIR214 | MIR215 | MIR216A | MIR216B | MIR217 | MIR217HG | MIR218-1 | MIR218-2 | MIR219A1 | MIR219A2 | MIR219B | MIR22 | MIR221 | MIR222 | MIR223 | MIR224
