Target Name: MEA1
NCBI ID: G4201
Other Name(s): Male-enhanced antigen 1 | male-enhanced antigen 1 | MEA1_HUMAN | Male-enhanced antigen (H-Y structural gene) | Male-enhanced antigen 1, transcript variant 1 | Male-enhanced antigen 1 (isoform 1) | MEA | MEA-1 | HYS | MEA1 variant 1

MEA1 as A Drug Target and Biomarker for Cancer

Male-enhanced antigen 1 (MEA1) is a protein that is expressed in human tissues and has been shown to play a role in the development and progression of various diseases, including cancer. While the exact function of MEA1 is not yet fully understood, research has identified several potential drug targets and biomarkers that may be involved in its regulation. In this article, we will explore the potential implications of MEA1 as a drug target and the research that has been conducted to study its role in disease.

Potential Drug Targets

MEA1 has been identified as a potential drug target due to its involvement in several cellular processes that are associated with the development of various diseases. One of the main drug targets for MEA1 is its role in cell signaling, particularly in the regulation of cell proliferation. MEA1 has been shown to play a negative role in cell proliferation, which may make it an attractive target for anti-cancer drugs.

MEA1 has also been shown to be involved in the regulation of cell apoptosis, which is the process by which cells die naturally. In cancer cells, the apoptosis process is often disrupted, leading to the survival and proliferation of cancer cells. By targeting MEA1, researchers may be able to disrupt this process and kill cancer cells.

Another potential drug target for MEA1 is its role in the regulation of cell migration. MEA1 has been shown to play a role in the migration of cancer cells to new sites of infection or tumors. By targeting MEA1, researchers may be able to inhibit the migration of cancer cells and reduce their ability to establish new tumors.

Biomarkers

MEA1 has also been identified as a potential biomarker for several diseases, including cancer. By measuring the level of MEA1 in patient tissues, researchers may be able to monitor the effectiveness of cancer treatments and identify potential biomarkers for disease progression.

One of the main biomarkers for cancer is the HER2 gene, which is often amplified in cancer cells. By targeting MEA1, researchers may be able to develop new treatments for cancer that specifically target this protein.

Another potential biomarker for cancer is the PD-L1 gene, which is often expressed in cancer cells. By targeting MEA1, researchers may be able to develop new treatments for cancer that specifically target this protein.

Conclusion

MEA1 is a protein that has been shown to play a role in the development and progression of various diseases, including cancer. While the exact function of MEA1 is not yet fully understood, research has identified several potential drug targets and biomarkers that may be involved in its regulation. Targeting MEA1 with small molecules or antibodies may be a promising new approach to the treatment of cancer and other diseases. Further research is needed to fully understand the role of MEA1 in disease and to develop new treatments based on this protein.

Protein Name: Male-enhanced Antigen 1

Functions: May play an important role in spermatogenesis and/or testis development

More Common Targets

MEAF6 | MEAF6P1 | MEAK7 | Mechanoelectrical transducer (MET) channel | Mechanosensitive Ion Channel | MECOM | MECOM-AS1 | MeCP1 histone deacetylase (HDAC) complex | MECP2 | MECR | MED1 | MED10 | MED11 | MED12 | MED12L | MED13 | MED13L | MED14 | MED14P1 | MED15 | MED15P8 | MED16 | MED17 | MED18 | MED19 | MED20 | MED21 | MED22 | MED23 | MED24 | MED25 | MED26 | MED27 | MED28 | MED29 | MED30 | MED31 | MED4 | MED4-AS1 | MED6 | MED7 | MED8 | MED9 | MEDAG | Mediator Complex | Mediator of RNA Polymerase II Transcription | MEF2A | MEF2B | MEF2C | MEF2C-AS1 | MEF2C-AS2 | MEF2D | MEFV | MEG3 | MEG8 | MEG9 | MEGF10 | MEGF11 | MEGF6 | MEGF8 | MEGF9 | MEI1 | MEI4 | MEIG1 | MEIKIN | MEIOB | MEIOC | MEIOSIN | MEIS1 | MEIS1-AS2 | MEIS1-AS3 | MEIS2 | MEIS3 | MEIS3P1 | MEIS3P2 | Melanin | Melanin-concentrating hormone (MCH) receptor | Melanocortin receptor | Melanoma-Associated Antigen | Melatonin receptor | MELK | MELTF | MELTF-AS1 | Membrane-Bound Protein Tyrosine Phosphatases (rPTPs) | Membrane-spanning 4-domains subfamily A member 4A | MEMO1 | MEMO1P1 | MEMO1P4 | MEMO1P5 | MEN1 | MEOX1 | MEOX2 | MEP1A | MEP1AP2 | MEP1AP4 | MEP1B | MEPCE | MEPE | MERTK | MESD