MYBPC1 Regulates Myosin Filament Formation and Contributes To Muscle Growth and Aging
MYBPC1 Regulates Myosin Filament Formation and Contributes To Muscle Growth and Aging
Myosin-binding protein C (MYBPC1) is a protein that is expressed in muscle cells and is known for its role in the regulation of muscle growth and maintenance. It is a member of the myosin-binding protein gene family, which is a family of proteins that are involved in the regulation of muscle function.MYBPC1 is expressed in slow skeletal-type muscle, which is the type of muscle that is responsible for providing sustained force throughout the body.
MYBPC1 is a 20-kDa protein that is expressed in muscle cells of various organisms, including humans. It is characterized by a unique N-terminus that consists of a 21 amino acid residue, as well as a C-terminus that is composed of a variable number of amino acids. The C-terminus of MYBPC1 is known to be involved in the formation of a complex with a protein called myosin, which is a key component of the myosin filament that is responsible for muscle contraction.
MYBPC1 is involved in the regulation of muscle growth and maintenance by promoting the assembly and disassembly of myosin filaments. It does this by interacting with a protein called myosin regulatory protein (MYR), which is also known as T-complex protein.MYBPC1 helps to regulate the number of myosin filaments that are present in muscle cells, which is important for determining the level of muscle force that can be generated.
MYBPC1 is also involved in the regulation of muscle aging and repair. It does this by interacting with a protein called muscle regulatory protein (MRP), which is known as transcription factor-4 (T-CF4). MYBPC1 helps to regulate the level of MRP that is present in muscle cells, which is important for maintaining muscle mass and strength in older adults.
MYBPC1 is a potential drug target and may also be a biomarker for a variety of muscle-related conditions, including muscle weakness, muscle pain, and muscle disease. Because it
Protein Name: Myosin Binding Protein C1
Functions: Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. Slow skeletal protein that binds to both myosin and actin (PubMed:31264822, PubMed:31025394). In vitro, binds to native thin filaments and modifies the activity of actin-activated myosin ATPase. May modulate muscle contraction or may play a more structural role
More Common Targets
MYBPC2 | MYBPC3 | MYBPH | MYBPHL | MYC | MYCBP | MYCBP2 | MYCBP2-AS1 | MYCBPAP | MYCL | MYCL-AS1 | MYCLP1 | MYCN | MYCNOS | MYCNUT | MYCT1 | MYD88 | MYDGF | MYEF2 | Myelin Protein | MYEOV | MYF5 | MYF6 | MYG1 | MYH1 | MYH10 | MYH11 | MYH13 | MYH14 | MYH15 | MYH16 | MYH2 | MYH3 | MYH4 | MYH6 | MYH7 | MYH7B | MYH8 | MYH9 | MYHAS | MYL1 | MYL10 | MYL11 | MYL12A | MYL12B | MYL12BP3 | MYL2 | MYL3 | MYL4 | MYL5 | MYL6 | MYL6B | MYL7 | MYL9 | MYLIP | MYLK | MYLK-AS1 | MYLK-AS2 | MYLK2 | MYLK3 | MYLK4 | MYLKP1 | MYMK | MYMX | MYNN | MYO10 | MYO15A | MYO15B | MYO16 | MYO16-AS1 | MYO16-AS2 | MYO18A | MYO18B | MYO19 | MYO1A | MYO1B | MYO1C | MYO1D | MYO1E | MYO1F | MYO1G | MYO1H | MYO3A | MYO3B | MYO3B-AS1 | MYO5A | MYO5B | MYO5C | MYO6 | MYO7A | MYO7B | MYO9A | MYO9B | MYOC | MYOCD | MYOD1 | MYOF | MYOG | MYOM1 | MYOM2