MIR424: A Non-Coding RNA Molecule as A Cancer Drug Target and Biomarker
MIR424: A Non-Coding RNA Molecule as A Cancer Drug Target and Biomarker
MicroRNA (miRNA) 424 (MIR424) is a non-coding RNA molecule that has been identified as a potential drug target and biomarker for various diseases, including cancer. MIR424 is a small molecule that can interact with various proteins, including activating transcription factor 3 (ATF3), a known regulator of cell growth and differentiation.
ATF3 is a protein that plays a crucial role in the development and maintenance of cancer cells. It is known to promote the growth and survival of cancer cells by inhibiting the negative effects of cell growth inhibitors, such as p53. MIR424 has been shown to interact with ATF3 and can alter its activity.
One of the key features of MIR424 is its ability to target specific regions of the genome. It has been shown to accumulate in the nuclei of cancer cells and to interact with the chromatin protein histone H3. MIR424 has also been shown to play a role in the regulation of gene expression by binding to specific miRNA targets.
In addition to its potential role as a drug target, MIR424 has also been identified as a potential biomarker for cancer. It has been shown to be expressed in various types of cancer, including breast, lung, and ovarian cancer. It is also overexpressed in cancer cells, which suggests that it may be a useful target for cancer therapies.
MIR424 has also been shown to play a role in the regulation of cellular processes that are important for cancer development. For example, it has been shown to be involved in the regulation of cell adhesion, a process that is critical for the development of cancer stem cells. It has also been shown to be involved in the regulation of cell apoptosis, a process that is important for the elimination of damaged or dysfunctional cells.
In conclusion, MIR424 is a small molecule that has the potential to be a drug target or biomarker for various diseases, including cancer. Its ability to interact with ATF3 and to target specific regions of the genome make it a promising candidate for drug development. Further research is needed to fully understand the role of MIR424 in cancer development and to develop effective therapies based on its properties.
Protein Name: MicroRNA 424
More Common Targets
MIR425 | MIR4251 | MIR4252 | MIR4253 | MIR4254 | MIR4255 | MIR4256 | MIR4257 | MIR4258 | MIR4259 | MIR4260 | MIR4261 | MIR4262 | MIR4263 | MIR4264 | MIR4265 | MIR4266 | MIR4267 | MIR4268 | MIR4269 | MIR4270 | MIR4271 | MIR4272 | MIR4273 | MIR4274 | MIR4275 | MIR4276 | MIR4277 | MIR4278 | MIR4279 | MIR4280 | MIR4281 | MIR4282 | MIR4283-1 | MIR4283-2 | MIR4284 | MIR4285 | MIR4286 | MIR4287 | MIR4288 | MIR4289 | MIR429 | MIR4290 | MIR4291 | MIR4292 | MIR4293 | MIR4294 | MIR4295 | MIR4296 | MIR4297 | MIR4298 | MIR4299 | MIR4300 | MIR4300HG | MIR4301 | MIR4302 | MIR4303 | MIR4304 | MIR4305 | MIR4306 | MIR4307 | MIR4308 | MIR4309 | MIR431 | MIR4310 | MIR4311 | MIR4312 | MIR4313 | MIR4314 | MIR4315-1 | MIR4315-2 | MIR4316 | MIR4317 | MIR4318 | MIR4319 | MIR432 | MIR4320 | MIR4321 | MIR4322 | MIR4323 | MIR4324 | MIR4325 | MIR4326 | MIR4327 | MIR4328 | MIR4329 | MIR433 | MIR4330 | MIR4418 | MIR4420 | MIR4423 | MIR4425 | MIR4427 | MIR4428 | MIR4429 | MIR4430 | MIR4431 | MIR4432 | MIR4432HG | MIR4433A
