GLRX5 Plays A Role in Cell Growth, Differentiation and Survival

Target Name: GLRX5

NCBI ID: G51218

GLRX5 Plays A Role in Cell Growth, Differentiation and Survival

GLRX5 (C14orf87) is a protein that is expressed in a variety of tissues throughout the body. It is a member of the GLR family of proteins, which are known for their role in intracellular signaling. GLRX5 has been shown to play a role in the regulation of cellular processes such as cell growth, differentiation, and survival.

One of the key functions of GLRX5 is its role in the regulation of cell growth. GLRX5 has been shown to play a negative role in the growth and proliferation of cancer cells. It has been shown to inhibit the activity of the oncogene transforming growth factor (TGF-2), which is a key regulator of cell growth and proliferation.

Another function of GLRX5 is its role in the regulation of cell differentiation. GLRX5 has been shown to play a role in the regulation of cell plasticity, which is the ability of cells to change and adapt to their environment. GLRX5 has been shown to promote the transition of stem cells to functional tissues, such as muscle and bone cells.

GLRX5 has also been shown to play a role in the regulation of cellular survival. GLRX5 has been shown to play a negative role in the regulation of cell survival, by inhibiting the activity of the survival protein p53. P53 is a key regulator of cellular stress and has been shown to play a critical role in the regulation of cell survival.

In addition to its role in cell growth, differentiation, and survival, GLRX5 has also been shown to play a role in the regulation of cellular interactions. GLRX5 is a member of the GLR family of proteins, which are known for their role in intracellular signaling. GLRX5 has been shown to play a role in the regulation of cellular interactions with other proteins, such as the protein PDGF-尾.

GLRX5 has also been shown to play a role in the regulation of cellular processes such as cell adhesion, migration and invasion. GLRX5 has been shown to promote the stickiness of cells to adherens junctions, which are specialized structures that form on the cell surface that help to maintain cell-cell contact and promote the movement of cells along the body.

In conclusion, GLRX5 is a protein that plays a critical role in the regulation of cellular processes such as cell growth, differentiation, survival, and interactions. Its functions have been studied extensively in the context of various diseases, including cancer, and its potential as a drug target or biomarker is being investigated. Further research is needed to fully understand the role of GLRX5 in these processes and to develop effective treatments for these diseases.

Protein Name: Glutaredoxin 5

Functions: Monothiol glutaredoxin involved in mitochondrial iron-sulfur (Fe/S) cluster transfer (PubMed:20364084, PubMed:23615440). Receives 2Fe/2S clusters from scaffold protein ISCU and mediates their transfer to apoproteins, to the 4Fe/FS cluster biosynthesis machinery, or export from mitochondrion (PubMed:20364084, PubMed:23615440, PubMed:24334290). Required for normal regulation of hemoglobin synthesis by the iron-sulfur protein ACO1 (PubMed:20364084)

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