Target Name: EPS8L1
NCBI ID: G54869
Other Name(s): epidermal growth factor receptor pathway substrate 8-related protein 1 | EPS8L1 variant 1 | FLJ20258 | DRC3 | ES8L1_HUMAN | PP10566 | EPS8-like protein 1 | EPS8R1 | MGC23164 | Epidermal growth factor receptor kinase substrate 8-like protein 1 (isoform a) | EPS8 like 1 | EPS8-related protein 1 | Epidermal growth factor receptor kinase substrate 8-like protein 1 | Epidermal growth factor receptor pathway substrate 8-related protein 1 | EPS8 like 1, transcript variant 1 | MGC4642

EPS8L1: A Potential Drug Target and Biomarker for the Epidermal Growth Factor Receptor Pathway

The Epidermal Growth Factor (EGF) receptor is a transmembrane protein that plays a crucial role in cell growth, development, and survival. EGF is a potent cytoplasmic factor that stimulates the production of new skin cells, hair, and nails. The EGF receptor is involved in many cellular processes, including cell adhesion, migration, and survival. The EGF receptor is also a target for many diseases, including cancer, neurodegenerative diseases, and skin diseases.

EPS8L1 is a protein that is expressed in various tissues, including skin, hair, and nails. It is a 21-kDa transmembrane protein that is derived from the EGF receptor. EPS8L1 has been shown to play a role in several cellular processes, including cell adhesion, migration, and survival.

Drug Targeting

EPS8L1 has been identified as a potential drug target for several reasons. Firstly, EPS8L1 is a protein that is expressed in various tissues, including skin, hair, and nails, making it an attractive target for small molecule inhibitors. Secondly, EPS8L1 has been shown to play a role in several cellular processes that are involved in cancer, neurodegenerative diseases, and skin diseases, making it an attractive target for therapeutic interventions.

Biomarker

EPS8L1 has also been identified as a potential biomarker for several diseases. For example, EPS8L1 has been shown to be overexpressed in several types of cancer, including breast, ovarian, and prostate cancer. Additionally, EPS8L1 has been shown to be involved in several diseases, including neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease.

Functional assays

To determine the function of EPS8L1, several studies have been conducted. One study showed that EPS8L1 was involved in cell adhesion and migration. Another study showed that EPS8L1 was involved in the regulation of cell survival.

Conclusion

In conclusion, EPS8L1 is a protein that has been shown to play a role in several cellular processes, including cell adhesion, migration, and survival. Based on these findings, EPS8L1 is an attractive target for small molecule inhibitors and a potential biomarker for several diseases. Further research is needed to fully understand the function of EPS8L1 and its potential as a drug target and biomarker.

Protein Name: EPS8 Like 1

Functions: Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton

More Common Targets

EPS8L2 | EPS8L3 | EPSTI1 | EPX | EPYC | EQTN | ER Membrane Protein Complex | ERAL1 | ERAP1 | ERAP2 | ERAS | ERBB2 | ERBB3 | ERBB4 | ERBIN | ERC1 | ERC2 | ERC2-IT1 | ERCC1 | ERCC2 | ERCC3 | ERCC4 | ERCC5 | ERCC6 | ERCC6L | ERCC6L2 | ERCC6L2-AS1 | ERCC8 | EREG | ERF | ERFE | ERG | ERG28 | ERGIC1 | ERGIC2 | ERGIC3 | ERH | ERHP1 | ERI1 | ERI2 | ERI3 | ERICH1 | ERICH2 | ERICH3 | ERICH4 | ERICH5 | ERICH6 | ERICH6-AS1 | ERICH6B | ERLEC1 | ERLIN1 | ERLIN2 | ERLNC1 | ERMAP | ERMARD | ERMN | ERMP1 | ERN1 | ERN2 | ERO1A | ERO1B | ERP27 | ERP29 | ERP44 | ERRFI1 | ERV3-1 | ERVFRD-1 | ERVK-6 | ERVK13-1 | ERVMER34-1 | ERVV-1 | ERVV-2 | ERVW-1 | ESAM | ESAM-AS1 | ESCO1 | ESCO2 | ESCRT-0 complex | ESCRT-I complex | ESCRT-II complex | ESCRT-III complex | ESD | ESF1 | ESM1 | ESPL1 | ESPN | ESPNL | ESPNP | ESR1 | ESR2 | ESRG | ESRP1 | ESRP2 | ESRRA | ESRRB | ESRRG | ESS2 | Estrogen receptor | Estrogen-related receptor (ERR) (nonspecifed subtype) | ESX1