Target Name: RPE
NCBI ID: G6120
Other Name(s): Ribulose-phosphate 3-epimerase | RPE_HUMAN | Xylulose phosphate 3-epimerase | D-xylulose-5-phosphate 3-epimerase | Ribulose-5-phosphate-3-epimerase, transcript variant 1 | Ribulose-phosphate 3-epimerase (isoform 1) | RPE2-1 | Ribulose 5-phosphate 3-epimerase | D-ribulose phosphate-3-epimerase | Erythrose-4-phosphate isomerase | RPE variant 1 | ribulose-5-phosphate-3-epimerase | Pentose-5-phosphate 3-epimerase | Ribulose-5-phosphate-3-epimerase | Phosphoribulose epimerase | D-ribulose 5-phosphate epimerase | D-ribulose-5-P 3-epimerase | Phosphoketopentose 3-epimerase | Phosphoketopentose epimerase

RPE: A Potential Drug Target for Various Diseases

Ribulose-phosphate 3-epimerase (RPE) is a gene that encodes a protein involved in the metabolism of carbohydrates, specifically glucose. RPE is a key enzyme in the glycolytic pathway, a critical pathway for cellular energy metabolism. Mutations in the RPE gene have been linked to various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases. As a result, RPE has emerged as a promising drug target for the treatment of various diseases.

The RPE gene is located on chromosome 16 and encodes a protein with 21 amino acid residues. The protein has a molecular weight of 34 kDa and a calculated pI of 6.5. RPE is expressed in most tissues of the body and is primarily localized to the cytoplasm. The cytoplasm is the fluid inside the cell that contains the cell's organelles, including the mitochondria, ribosomes, and endoplasmic reticulum.

RPE is involved in the metabolism of glucose, which is the body's primary energy source. The glucose molecule is broken down into two

Protein Name: Ribulose-5-phosphate-3-epimerase

Functions: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate

More Common Targets

RPE65 | RPEL1 | RPF1 | RPF2 | RPGR | RPGRIP1 | RPGRIP1L | RPH3A | RPH3AL | RPH3AL-AS1 | RPIA | RPL10 | RPL10A | RPL10AP10 | RPL10AP12 | RPL10AP3 | RPL10AP6 | RPL10AP7 | RPL10AP9 | RPL10L | RPL10P13 | RPL10P16 | RPL10P2 | RPL10P4 | RPL10P6 | RPL10P9 | RPL11 | RPL11P4 | RPL12 | RPL12P32 | RPL12P38 | RPL12P6 | RPL12P7 | RPL13 | RPL13A | RPL13AP16 | RPL13AP17 | RPL13AP20 | RPL13AP22 | RPL13AP23 | RPL13AP25 | RPL13AP3 | RPL13AP5 | RPL13AP6 | RPL13AP7 | RPL13P12 | RPL13P5 | RPL13P6 | RPL14 | RPL14P1 | RPL14P3 | RPL15 | RPL15P11 | RPL15P20 | RPL15P21 | RPL15P22 | RPL15P3 | RPL15P4 | RPL17 | RPL17P25 | RPL17P33 | RPL17P34 | RPL17P39 | RPL17P4 | RPL17P44 | RPL17P49 | RPL17P7 | RPL17P8 | RPL18 | RPL18A | RPL18AP16 | RPL18AP3 | RPL18AP6 | RPL18AP8 | RPL18P1 | RPL18P13 | RPL18P4 | RPL19 | RPL19P12 | RPL19P21 | RPL19P4 | RPL19P8 | RPL21 | RPL21P108 | RPL21P119 | RPL21P131 | RPL21P133 | RPL21P134 | RPL21P14 | RPL21P16 | RPL21P19 | RPL21P2 | RPL21P20 | RPL21P28 | RPL21P33 | RPL21P39 | RPL21P42 | RPL21P44 | RPL21P53 | RPL21P7