Understanding The Potential Role of MIR455 in Human Health (G619556)
Understanding The Potential Role of MIR455 in Human Health
MIR455, also known as hsa-mir-455, is a non-coding RNA molecule that has been identified as a potential drug target or biomarker for various diseases, including cancer. Its unique structure and function have made it an attractive target for researchers to study, and recent studies have shed light on its potential implications for human health.
MIR455 is a microRNA (miRNA), a small non-coding RNA molecule that plays a critical role in regulating gene expression. MiRNAs are designed to target specific mRNAs for degradation, and their levels are often reduced in cancer cells compared to healthy cells. This loss of normal miRNA levels is thought to contribute to the development and progression of cancer.
One of the defining features of MIR455 is its unique structure. It is composed of 20 amino acid residues and has a calculated molecular weight of 23.9 kilodaltons (kDa). MIR455 is predominantly composed of a single isoleucine residue, which is a key amino acid for the structure and stability of proteins. The unique shape and size of MIR455 have made it difficult to predict its function, but studies have suggested that it may have a structural role in the regulation of gene expression.
MIR455 has been shown to play a role in the regulation of various genes, including the TGF-β pathway. TGF-β is a well-known transcription factor that regulates cell growth, differentiation, and inflammation. MIR455 has been shown to physically interact with the TGF-β transcription factor and has been shown to play a role in the regulation of TGF-β-mediated gene expression.
In addition to its role in the TGF-β pathway, MIR455 has also been shown to be involved in the regulation of cell apoptosis, which is the process by which cells die when they have reached their lifespan. MIR455 has been shown to play a role in the regulation of cell apoptosis by targeting the Bcl-2 protein. Bcl-2 is a well-known protein that has been implicated in the regulation of cell apoptosis, and MIR455 has been shown to interact with it and contribute to its function.
MIR455 has also been shown to be involved in the regulation of cell signaling pathways, including the ERK signaling pathway. ERK is a well-known protein that is involved in the regulation of cell growth, differentiation, and survival. MIR455 has been shown to play a role in the regulation of ERK signaling by targeting the p21 protein.
In conclusion, MIR455 is a non-coding RNA molecule that has been identified as a potential drug target or biomarker for various diseases. Its unique structure and function have made it an attractive target for researchers to study, and recent studies have shed light on its potential implications for human health. Further research is needed to fully understand the role of MIR455 in the regulation of gene expression and the development and progression of disease.
Protein Name: MicroRNA 455
More Common Targets
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