RPS20: A Potential Drug Target and Biomarker (G6224)

Target Name: RPS20

NCBI ID: G6224

RPS20: A Potential Drug Target and Biomarker

RPS20 (Ribosomal Protective protein 20) is a protein that is expressed in various cell types of the human body, including muscle cells, nerve cells, and red blood cells. It is a member of the superfamily of proteins known as the Ribosomal Protective protein ( RPP) family, which is characterized by the presence of a nucleotide-binding oligomerization domain (NBO domain) and a conserved acid-rich C-terminus.

The RPP family is involved in various cellular processes, including the regulation of protein translation, DNA replication, and cell survival. RPS20 is specifically known for its role in protecting the ribosome from various types of damage, such as those modified by post-translational modification of RNA caused damage.

Drug Targeting

RPS20 has been identified as a potential drug target due to its unique structure and its involvement in various cellular processes. One of the main reasons for its potential as a drug target is its high prohibitive activity and its ability to bind to a variety of proteins, including Some post-translationally modified proteins.

By binding to these proteins, RPS20 can inhibit their translation, thereby inhibiting disease progression. In addition, RPS20 can also bind to certain drug molecules, thereby improving the efficacy of these drugs.

Biomarker

RPS20 may also serve as a potential biomarker to detect disease progression. Because its activity is affected by multiple factors, such as cell type, environment, etc., it can be used to detect the severity of disease and the effectiveness of treatments.

Conclusion

RPS20 is a protein that has great potential as a drug target due to its unique structure and its involvement in various cellular processes. Its active properties make it an attractive target for drug development. Further research is needed to fully understand its role in disease progression and its potential as a biomarker.

Protein Name: Ribosomal Protein S20

Functions: Component of the small ribosomal subunit (PubMed:23636399). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399)

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