Target Name: MIR378H
NCBI ID: G100616306
Other Name(s): hsa-mir-378h | MicroRNA 378h | hsa-miR-378h | microRNA 378h

MIR378H: A Potential Drug Target and Biomarker

MIR378H is a protein that is expressed in various tissues of the body, including the brain, heart, and lungs. Its primary function is to regulate the migration of immune cells, specifically natural killer cells (NK cells), to sites of infection or damage. MIR378H has been identified as a potential drug target due to its unique structure and its involvement in the immune response.

The immune system is a critical component of the body's defense against infection and disease. The immune system consists of a variety of different cell types, including T cells, B cells, natural killer cells, and macrophages. These cells play important roles in detecting and responding to potential threats in the body, such as viruses, bacteria, and cancer cells.

MIR378H is a member of the immunoglobulin superfamily, which includes a variety of proteins that are involved in the immune response. It is made up of four domains: an extracellular domain that is responsible for interacting with other proteins, a transmembrane domain that is involved in the formation of a complex with the cell membrane, and two intracellular domains that are involved in the regulation of the immune response.

One of the intracellular domains of MIR378H is known as the N-terminus transmembrane domain. This domain is responsible for the formation of a complex with the cell membrane, which is thought to play an important role in the regulation of the immune response. MIR378H has been shown to be involved in the regulation of natural killer cell (NK) function, which is a critical part of the immune system's response to infection and disease.

NK cells are a type of immune cell that play an important role in detecting and responding to potential threats in the body. They are characterized by their ability to recognize and destroy infected or damaged cells, without the need for any further activation. MIR378H is thought to be involved in the regulation of NK cell function by controlling the movement of NK cells to the site of infection or damage.

In addition to its involvement in NK cell function, MIR378H has also been shown to be involved in the regulation of other immune cell functions. For example, it has been shown to play a role in the regulation of T cell function, which is responsible for the development and activation of T cells, the most important type of immune cell.

MIR378H has also been shown to be involved in the regulation of inflammation. It has been shown to play a role in the regulation of the production of pro-inflammatory cytokines, which are important in the inflammatory response. MIR378H has also been shown to be involved in the regulation of the production of anti-inflammatory cytokines, which are important in the immune response.

Due to its involvement in the regulation of immune cell function, MIR378H has been identified as a potential drug target. By targeting MIR378H with small molecules or other compounds, it may be possible to inhibit its ability to regulate immune cell function and improve the immune response to infection and disease.

In conclusion, MIR378H is a protein that is expressed in various tissues of the body and is involved in the regulation of the immune response. Its unique structure and its involvement in the regulation of natural killer cells, T cells, and inflammation make it a promising target for drug development. Further research is needed to fully understand the role of MIR378H in the immune response and to develop safe and effective drugs that can target it.

Protein Name: MicroRNA 378h

More Common Targets

MIR378I | MIR379 | MIR380 | MIR381 | MIR382 | MIR383 | MIR384 | MIR3907 | MIR3908 | MIR3909 | MIR3910-1 | MIR3910-2 | MIR3911 | MIR3912 | MIR3913-1 | MIR3913-2 | MIR3914-1 | MIR3914-2 | MIR3915 | MIR3916 | MIR3917 | MIR3918 | MIR3919 | MIR3920 | MIR3921 | MIR3922 | MIR3923 | MIR3924 | MIR3925 | MIR3926-1 | MIR3926-2 | MIR3927 | MIR3928 | MIR3929 | MIR3934 | MIR3935 | MIR3936 | MIR3936HG | MIR3937 | MIR3938 | MIR3939 | MIR3940 | MIR3941 | MIR3942 | MIR3943 | MIR3944 | MIR3945 | MIR3945HG | MIR3960 | MIR3972 | MIR3973 | MIR3974 | MIR3976 | MIR3976HG | MIR3977 | MIR3978 | MIR409 | MIR410 | MIR411 | MIR412 | MIR421 | MIR422A | MIR423 | MIR424 | MIR425 | MIR4251 | MIR4252 | MIR4253 | MIR4254 | MIR4255 | MIR4256 | MIR4257 | MIR4258 | MIR4259 | MIR4260 | MIR4261 | MIR4262 | MIR4263 | MIR4264 | MIR4265 | MIR4266 | MIR4267 | MIR4268 | MIR4269 | MIR4270 | MIR4271 | MIR4272 | MIR4273 | MIR4274 | MIR4275 | MIR4276 | MIR4277 | MIR4278 | MIR4279 | MIR4280 | MIR4281 | MIR4282 | MIR4283-1 | MIR4283-2 | MIR4284