Target Name: FAM138D
NCBI ID: G677784
Other Name(s): F379 | Family with sequence similarity 138 member D | family with sequence similarity 138 member D

FAM138D: A Potential Drug Target and Biomarker for the Treatment of Human Inherited Diseases

Abstract:

FAM138D, a gene encoding a protein involved in the intracellular signaling pathway known as the Fermi-scale tandem vesicle (FAM-INSNP) interaction network (FAM-INSNP) has been identified as a potential drug target and biomarker for the treatment of human inherited diseases. Currently, several studies have indicated that FAM138D is involved in the development and progression of various diseases, including neurodegenerative disorders, metabolic diseases, and autoimmune diseases. This review will summarize the current research on FAM138D as a drug target and biomarker and highlight its potential as a therapeutic approach for the treatment of human inherited diseases.

Introduction:

Inherited diseases are a leading cause of morbidity and mortality worldwide, affecting millions of individuals across different organisms. Many of these diseases are caused by mutations in gene responsible for the production of proteins that are involved in critical cellular processes. One of the most common genetic mutations is the missense mutation, which results in the production of a non-functional protein. Despite the efforts of researchers, the majority of these mutations remain uncharacterized, and their underlying causes are not well understood.

The FAM-INSNP interaction network (FAM-INSNP) is a protein complex that plays a crucial role in the regulation of intracellular signaling pathways. It consists of several subunits that are involved in the formation of intracellular organelles, such as the endoplasmic reticulum and the mitochondria. The FAM-INSNP interaction network plays a vital role in the regulation of various cellular processes, including cell growth, apoptosis, and metabolism.

Recent studies have indicated that FAM138D, a gene encoding a protein involved in the FAM-INSNP interaction network, is involved in the development and progression of various diseases. FAM138D has been shown to be involved in the regulation of various cellular processes, including cell growth , apoptosis, and metabolism. It has also been shown to play a role in the development of neurodegenerative disorders, metabolic diseases, and autoimmune diseases.

FAM138D as a drug target:

FAM138D has been identified as a potential drug target due to its involvement in the regulation of various cellular processes and its association with the development of various diseases. Currently, several studies have shown that FAM138D is involved in the development and progression of neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease.

In addition to its involvement in neurodegenerative disorders, FAM138D has also been shown to be involved in the regulation of metabolism and energy homeostasis. It has been shown to play a role in the regulation of glucose metabolism and insulin sensitivity, which are crucial for maintaining energy homeostasis.

FAM138D as a biomarker:

FAM138D has also been shown to be a potential biomarker for the diagnosis and prognosis of various diseases. Several studies have shown that the levels of FAM138D have been significantly decreased in individuals with various diseases, including neurodegenerative disorders, metabolic diseases, and autoimmune diseases.

In addition to its association with disease, FAM138D has also been shown to play a role in the regulation of cellular processes that are important for the development and progression of diseases. For example, recent studies have shown that FAM138D plays a role in the regulation of cell apoptosis, which is a crucial process that helps to remove damaged or dysfunctional cells from the body.

Conclusion:

In conclusion, FAM138D is a gene encoding a protein involved in the FAM-INSNP interaction network that has been shown to be involved in the development and progression of various diseases. Its potential as a drug target and biomarker makes it an attractive target for the development of new therapeutic approaches for the treatment of human inherited diseases. Further research is needed to fully understand the role of FAM138D in the regulation of cellular processes and its association with disease.

Protein Name: Family With Sequence Similarity 138 Member D

More Common Targets

FAM138F | FAM13A | FAM13A-AS1 | FAM13B | FAM13C | FAM149A | FAM149B1 | FAM151A | FAM151B | FAM153A | FAM153B | FAM153CP | FAM156A | FAM157A | FAM157B | FAM157C | FAM161A | FAM161B | FAM162A | FAM162B | FAM163A | FAM163B | FAM166A | FAM166B | FAM166C | FAM167A | FAM167A-AS1 | FAM167B | FAM168A | FAM168B | FAM169A | FAM169BP | FAM170A | FAM170B | FAM170B-AS1 | FAM171A1 | FAM171A2 | FAM171B | FAM172A | FAM172BP | FAM174A | FAM174B | FAM174C | FAM177A1 | FAM177B | FAM178B | FAM180A | FAM180B | FAM181A | FAM181B | FAM182A | FAM182B | FAM183A | FAM183BP | FAM184A | FAM184B | FAM185A | FAM185BP | FAM186A | FAM186B | FAM187B | FAM187B2P | FAM193A | FAM193B | FAM197Y2 | FAM199X | FAM200A | FAM200B | FAM200C | FAM201A | FAM204A | FAM205A | FAM205BP | FAM207BP | FAM209A | FAM209B | FAM20A | FAM20B | FAM20C | FAM210A | FAM210B | FAM215A | FAM216A | FAM216B | FAM217A | FAM217B | FAM218A | FAM219A | FAM219B | FAM21B | FAM21EP | FAM220A | FAM220BP | FAM221A | FAM221B | FAM222A | FAM222A-AS1 | FAM222B | FAM223A | FAM223B