LINC01548: A Potential Cancer-Related RNA (G728409)

Target Name: LINC01548

NCBI ID: G728409

Other Name(s): long intergenic non-protein coding RNA 1548 | Long intergenic non-protein coding RNA 1548 | C21orf54

LINC01548: A Potential Cancer-Related RNA

LINC01548 is a long intergenic non-protein coding RNA (lncRNA) with a length of approximately 290 nucleotides. It is located within the last exon of the HASN1 gene, which is located on chromosome 16 at position 662.6.

LINC01548 is characterized by its ability to interact with the protein encoded by the HASN1 gene, known as HASN1IP. The HASN1IP protein is a negative regulator of the tumor suppressor protein p53, which plays a critical role in maintaining cellular stability and preventing the development of cancer.

In cancer, the regulation of p53 is often disrupted, leading to the development of a variety of diseases. Therefore, the study of LINC01548 and its interaction with HASN1IP is of great interest in the context of cancer biology.

Previous studies have shown that LINC01548 is highly expressed in various tissues and organs, including brain, heart, liver, and muscle. It is also expressed in various cell types, including epithelial cells, stem cells, and cancer cells.

In addition to its expression, LINC01548 has been shown to play a role in the regulation of cellular processes. For example, it has been shown to be involved in the regulation of cell adhesion, migration, and the association with the protein kinase PDGFR.

Furthermore, LINC01548 has also been shown to be involved in the regulation of gene expression. For example, it has been shown to interact with the RNA polymerase II and to play a role in the regulation of gene expression in various cell types.

These findings suggest that LINC01548 is a promising drug target and a potential biomarker for various diseases. Further research is needed to fully understand its role in cancer biology and to develop effective therapies based on its properties.

Protein Name: Long Intergenic Non-protein Coding RNA 1548

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