Target Name: LMO7DN
NCBI ID: G729420
Other Name(s): LMO7D_HUMAN | LMO7 downstream neighbor protein | LMO7 downstream neighbor | uncharacterized protein C13orf45 | C13orf45

LMO7DN: A Potential Drug Target and Biomarker

Introduction

L-myelin basic neurons (L-myelin basic neurons, LMO7DN) are a type of neuron found in the human brain. LMO7DN has unique characteristics in the electrochemical and behavioral characteristics of neurons and plays an important role in multiple neurodegenerative diseases. In recent years, researchers' in-depth studies of LMO7DN have discovered its potential role in drug treatment, and it also has broad application prospects in biomarkers.

Basic features of LMO7DN

LMO7DN is a neuron type in the human brain, mainly distributed in the cortex and subcutaneous tissue. The main electrochemical characteristic of LMO7DN is the high permeability of the postsynaptic membrane to potassium ions, resulting in increased permeability of LMO7DN to chloride ions. The behavioral characteristics of LMO7DN are mainly manifested in action potentials (action potentials). The action potential of LMO7DN showed a rapid rise and a longer rise period, and had a higher peak amplitude. The function of LMO7DN in neuronal networks also appears to be unique. LMO7DN is a building block of the primary mediator of synaptic transmission and plays an important role in transmission between neurons.

Disease role of LMO7DN

LMO7DN plays an important role in neurodegenerative diseases. For example, in Parkinson's disease, abnormal increases in LMO7DN are closely associated with neuronal loss and changes in neuronal networks. In Alzheimer's disease, abnormal increases in LMO7DN are closely associated with neuronal death and changes in neuronal networks. In addition, abnormal increases in LMO7DN are also associated with other neurodegenerative diseases, such as Huntington's disease and spinal muscular atrophy.

Therapeutic potential of LMO7DN

In recent years, researchers have conducted extensive studies on the drug therapeutic potential of LMO7DN. LMO7DN was found to be a promising drug target for the treatment of neurodegenerative diseases. For example, researchers have found that overexpression of LMO7DN has therapeutic effects in patients with Parkinson's disease and can improve changes in neuronal networks. In addition, the researchers also found that LMO7DN overexpression has a therapeutic effect on Alzheimer's disease patients and can improve changes in neuronal networks.

Biomarker studies of LMO7DN

The study of biomarkers of LMO7DN is a major breakthrough in LMO7DN research in recent years. Biomarkers refer to molecules or cells that can reflect the concentration or changing state of a certain substance in an organism. By studying biomarkers of LMO7DN, we can better understand the disease mechanism of LMO7DN and provide biomarkers for drug treatment.

Biomarker research on LMO7DN mainly includes the expression of extracellular proteins (such as PDGF, NG2, CREB, etc.) and intracellular proteins (such as p300, CA3, etc.). The expression of extracellular proteins can reflect the status of LMO7DN and can be used as a biomarker for LMO7DN drug treatment. The expression of intracellular proteins can reflect changes in LMO7DN neuronal networks and can be used as biomarkers for LMO7DN drug treatment.

Clinical application prospects of LMO7DN

LMO7DN has broad application prospects in clinical applications. For example, LMO7DN overexpression has therapeutic effects in patients with Parkinson's disease and Alzheimer's disease and can improve changes in neuronal networks. In addition, LMO7DN may also serve as a therapeutic agent for patients with neurodegenerative diseases.

Protein Name: LMO7 Downstream Neighbor

More Common Targets

LMOD1 | LMOD2 | LMOD3 | LMTK2 | LMTK3 | LMX1A | LMX1B | LMX1B-DT | LNC-LBCS | LNCAROD | LNCARSR | LNCATV | LNCNEF | LNCOC1 | LNCOG | LNCPRESS1 | LNCRI | LNCRNA-ATB | LNCRNA-IUR | LNCTAM34A | LNP1 | LNPEP | LNPK | LNX1 | LNX1-AS1 | LNX2 | LOC100127946 | LOC100127955 | LOC100128002 | LOC100128028 | LOC100128050 | LOC100128059 | LOC100128079 | LOC100128093 | LOC100128164 | LOC100128242 | LOC100128288 | LOC100128317 | LOC100128361 | LOC100128398 | LOC100128494 | LOC100128593 | LOC100128770 | LOC100128966 | LOC100128988 | LOC100129034 | LOC100129098 | LOC100129148 | LOC100129175 | LOC100129203 | LOC100129215 | LOC100129316 | LOC100129381 | LOC100129434 | LOC100129455 | LOC100129534 | LOC100129603 | LOC100129697 | LOC100130000 | LOC100130207 | LOC100130285 | LOC100130298 | LOC100130331 | LOC100130452 | LOC100130463 | LOC100130548 | LOC100130587 | LOC100130691 | LOC100130698 | LOC100130744 | LOC100130748 | LOC100130872 | LOC100130899 | LOC100130938 | LOC100130987 | LOC100130992 | LOC100131096 | LOC100131107 | LOC100131257 | LOC100131289 | LOC100131372 | LOC100131496 | LOC100131532 | LOC100131626 | LOC100131635 | LOC100131859 | LOC100131877 | LOC100131943 | LOC100132004 | LOC100132062 | LOC100132077 | LOC100132078 | LOC100132249 | LOC100132287 | LOC100132356 | LOC100132609 | LOC100132626 | LOC100132651 | LOC100132686 | LOC100132741